Results 91 to 100 of about 107,649 (340)

Transdermal cold atmospheric plasma-mediated immune checkpoint blockade therapy

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance Strategies to improve efficacy and reduce side effects of immune checkpoint blockade (ICB) therapy are clinically relevant. Here, we described a transdermal cold atmospheric plasma (CAP)-mediated ICB therapy.
Guojun Chen, Zhitong Chen, Di Wen, Zejun Wang, Hong-Jun Li, Yi Zeng, G. Dotti, R. Wirz, Zhen Gu   +8 more
semanticscholar   +1 more source

Transdermal delivery by iontophoresis

Indian Journal of Pharmaceutical Sciences, 2008
Recently there has been an increased interest in using iontophoretic technique for the transdermal delivery of medications, both ionic and nonionic. This article is an overview of the history of iontophoresis and factors affecting iontophoretic drug transfer for the systemic effects and laws for development of Transdermal delivery system are discussed.
Rawat, Swati, Vengurlekar, Sudha, Rakesh, B., Jain, S., Srikarti, G.   +4 more
openaire   +3 more sources

Bioengineered Interfaces for Peripheral Nerve Sensory Restoration

Advanced Materials, EarlyView.
Half of amputees abandon their prosthetics for lack of feeling. This review charts the full path from peripheral nerve injury to restored sensation, through surgical, regenerative, noninvasive, and implanted approaches, and shows how injury type and interface material properties determine which strategy can deliver naturalistic feedback, and why ...
Sydney Swedick, Salim El Hadwe, Kesi Liang, George G. Malliaras, Damiano G. Barone   +4 more
wiley   +1 more source

Soft and Transient Bioelectronics Enabled by Polymer‐Free Ti3C2Tx MXene Hydrogels

Advanced Materials, EarlyView.
We present Ti3C2Tx MXene hydrogel (MXgel) bioelectronics, a soft, flexible, and fully transient platform for high‐fidelity neural recording and stimulation. MXgel bioelectronics exhibit exceptional electrical conductivities, low electrochemical impedances, and high charge injection capacities.
Raghav Garg, Franco A. Laimo, Stefano Ippolito, Prastuti Upadhyay, Spencer R. Averbeck, Dimitris Boufidis, Charles‐Antoine Assenmacher, Dayo O. Adewole, Sai Panigrahy, Bita Soltan Mohammadlou, Lucy Plant, Yuan Zhang, Andrew G. Richardson, Yury Gogotsi, D. Kacy Cullen, Flavia Vitale   +15 more
wiley   +1 more source

Recent Advances of Slip Sensors for Smart Robotics

Advanced Materials Technologies, EarlyView.
This review summarizes recent progress in robotic slip sensors across mechanical, electrical, thermal, optical, magnetic, and acoustic mechanisms, offering a comprehensive reference for the selection of slip sensors in robotic applications. In addition, current challenges and emerging trends are identified to advance the development of robust, adaptive,
Xingyu Zhang, Liao Wu, Shuai He, Zhao Sha, Yuwan Huang, Shuying Wu, Dewei Chu, Chun H. Wang, Shuhua Peng   +8 more
wiley   +1 more source

Recent Advances in Transparent Microelectrode Device Architecture and Fabrication Strategies for Biomedical Applications

Advanced Materials Technologies, EarlyView.
Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan, Tran Bach Dang, Chi Cong Nguyen, Yee Lap Pong, Tianruo Guo, Thanh Nho Do, Hoang‐Phuong Phan   +6 more
wiley   +1 more source

Electroporation-delivered transdermal neostigmine in rats: equivalent action to intravenous administration

Drug Design, Development and Therapy, 2016
Szilvia Berkó,1,* Kálmán F Szűcs,2,* Boglárka Balázs,1,3 Erzsébet Csányi,1 Gábor Varju,4 Anita Sztojkov-Ivanov,2 Mária Budai-Szűcs,1 Judit Bóta,2 Róbert Gáspár2 ...
Berkó S, Szűcs KF, Balázs B, Csányi E, Varju G, Sztojkov-Ivanov A, Budai-Szűcs M, Bóta J, Gáspár R   +8 more
doaj  

Transdermal delivery of levosimendan

European Journal of Pharmaceutical Sciences, 2000
The aim of this study was to determine if transdermal penetration of levosimendan, a novel positive inotropic drug, could be enhanced and controlled by formulation modifications. Penetration of levosimendan across human epidermis in vitro was determined using abdominal excised skin and diffusion cells.
R, Valjakka-Koskela, J, Hirvonen, J, Mönkkönen, J, Kiesvaara, S, Antila, L, Lehtonen, A, Urtti   +6 more
openaire   +2 more sources

Bioinspired Adaptive Artificial Cilia With Tunable Sensitivity and Dynamic Range for Airflow Monitoring in the Central Airway

Advanced Materials Technologies, EarlyView.
A magnetically reconfigurable airflow sensor integrated with an airway stent enables tunable sensitivity and dynamic sensing range. Airflow‐induced cantilever deformation generates resistance changes, while an external magnetic field modulates sensor stiffness, enhancing sensitivity at low airflow velocities and extending the sensing range at higher ...
Darren Wang, Ruijian Ge, Shuda Dong, Zhongming Lyu, Yusheng Wang, Nicholas Strymish, Hanwen Fan, Fabien Maldonado, Caitlin T. Demarest, Yuxiao Zhou, Xiaoguang Dong   +10 more
wiley   +1 more source

Transdermal drug delivery of labetalol hydrochloride: Feasibility and effect of penetration enhancers

Journal of Pharmacy and Bioallied Sciences, 2010
Objectives : The objective of this study is to investigate the feasibility of transdermal drug delivery of Labetalol Hydrochloride (LHCl) and to study the effect of different penetration enhancers on the skin permeability of LHCl.
Saqib Zafar, Asgar Ali, Mohammed Aqil, Abdul Ahad   +3 more
doaj   +1 more source