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Ocular iontophoresis

Vestnik oftal'mologii, 2021
Iontophoresis in medicine is a combined pharmacological and physical method of treatment that unites the therapeutic effect of an electric current with the pharmacological effect of medicinal substances administered at the same time via an electric current. The article describes the physical basis of the therapeutic effect of direct electric current on
A.K. Drakon   +3 more
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Transdermal iontophoresis

Expert Opinion on Drug Delivery, 2005
Iontophoresis is a technique used to enhance the transdermal delivery of compounds through the skin via the application of a small electric current. By the process of electromigration and electro-osmosis, iontophoresis increases the permeation of charged and neutral compounds, and offers the option for programmed drug delivery.
Priya, Batheja   +5 more
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Iontophoresis

2007
Charged solutes are transported primarily by electrical repulsion from the electrode. The flow of electric current may enhance the permeability of skin. Electro-osmosis may alter the transport of unionized molecules and large polar peptides.
Angela Anigbogu, Howard Maibach
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Iontophoresis Treatment

Otolaryngology–Head and Neck Surgery, 1979
Iontophoresis can be used as a method of treating herpes simplex virus and aphthous gingivostomatitis. Idoxuridine has been used for herpes simplex virus, and corticosteroids and antibiotics have been used for aphthous stomatitis. Levamisole hydrochloride has been used for both herpes simplex virus and recurrent aphthous stomatitis.A lidocaine and ...
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PENICILLIN BY IONTOPHORESIS

Journal of the American Medical Association, 1946
To the Editor:— The subject of iontophoresis (ionization) of penicillin should be clarified, as there are references in the literature regarding the efficacy of this method of application (von Sallmann, Ludwig, and Meyer, Karl: Penetration of Penicillin into the Eye,Arch. Ophth.31:1 [Jan.] 1944. Dunnington, J.
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Iontophoresis in Ophthalmology

American Journal of Ophthalmology, 1951
The treatment of ocular disease by ion­ tophoresis has assumed increasing impor­ tance with the advent of chemotherapy and the antibiotics. Ion transfer of these drugs often serves to introduce them into the globe in concentrations greater than can be ob­ tained by any other method short of actual inoculation.
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Transdermal Iontophoresis

Clinical Pharmacokinetics, 1994
The science of transdermal drug delivery has received much attention in the past 2 decades. Drugs such as scopolamine (hyoscine), nitroglycerin (glyceryl trinitrate), estradiol, nicotine and clonidine are now available commercially as transdermal patches.
P, Singh, H I, Maibach
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Transdermal iontophoresis revisited

Current Opinion in Chemical Biology, 2000
Iontophoresis evolved as a transdermal enhancement technique in the 20th century, primarily for the delivery of large and charged molecules. Significant achievements have been made in the understanding of underlying mechanisms of iontophoresis and these have contributed to the rational development of iontophoretic delivery systems. The major challenges
R, Panchagnula   +3 more
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Iontophoresis: electrorepulsion and electroosmosis

Journal of Controlled Release, 2000
Over the last 10-15 years, the electrical enhancement of drug delivery across the skin has undergone intense investigation. During this period, considerable amounts of experimental data have been generated, and the successful enhancement of a diverse array of molecules has been achieved.
Guy, Richard H.   +5 more
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Transscleral Iontophoresis of Foscarnet

American Journal of Ophthalmology, 1993
Current local treatments of cytomegalovirus retinopathy may result in serious intraocular complications. Using an animal model, we investigated transscleral iontophoresis as a technique for delivery of foscarnet to the vitreous. Using a probe tip surface area of 0.19 mm2, a current of 1 mA, and a duration of ten minutes, transscleral iontophoresis of 0.
D, Sarraf   +4 more
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