Results 171 to 180 of about 9,735 (211)

A novel 6-pyrophosphorylating IP6 kinase (IP6-6K) discovered in the protozoon Trichomonas vaginalis

Molecular and Biochemical Parasitology, 2019
The parasitic protozoon Trichomonas vaginalis is the pathogen of trichomoniasis, the most common non-viral, sexually transmitted disease in humans. Inositol phosphates function in the pathomechanisms of a number of human pathogenic protozoa. Recent findings point to a role of inositol phosphates in T.
Torsten Wundenberg, Marcus M. Nalaskowski, Benjamin Löser, Werner Fanick, Thomas Hackl, Ursula Fürnkranz, Christoph Rehbach, Hongying Lin, Georg W. Mayr   +8 more
openaire   +2 more sources

Inositol Hexaphosphate (IP6) Inhibits Cellular Proliferation In Melanoma

Journal of Surgical Research, 2006
Inositol Hexaphosphate (IP6) is a naturally occurring polyphosphorylated carbohydrate found in food sources high in fiber content. We have previously reported IP6 to have significant inhibitory effects against pancreatic cancer in vitro. We hypothesized that the IP6 would significantly inhibit cell growth of cutaneous melanoma in vitro.The melanoma ...
Irfan, Rizvi, Dale R, Riggs, Barbara J, Jackson, Alex, Ng, Cynthia, Cunningham, David W, McFadden   +5 more
openaire   +2 more sources

IP6 (Inositol Hexaphosphate) as a Signaling Molecule

Current Signal Transduction Therapy, 2012
Inositol hexaphosphate (IP6, InsP6) is a polyphosphorylated carbohydrate with diverse signaling properties. IP6 is plentiful in organisms as diverse as yeast, actinobacteria, mammals and plants. In the plant kingdom, IP6 accumulates during seed development; during germination it is broken down into lower inositol phosphates and micronutrients to ...
Abul Kalam Shamsuddin, Sanchita Bose
openaire   +1 more source

IP6 in Cancer Therapy: Past, Present and Future

Current Cancer Therapy Reviews, 2010
Inositol hexaphosphate (IP6) and its derivatives are naturally occurring, most abundant polyphosphorylated carbohydrates in organisms as diverse as yeast, endo-parasites, mammals and plants. IP6 represents a major metabolic pool in cellular phosphate pathways involved in vital functions such as signal transduction, regulation of cell proliferation and ...
Agata Matejuk, Abulkalam Shamsuddin
openaire   +1 more source

Antiplatelet activity of inositol hexaphosphate (IP6).

Anticancer research, 2000
Platelet adhesion to endothelial cells, their aggregation and subsequent release of platelet-derived mediators are key steps in the pathogenesis of thrombosis and atherosclerosis. Using impedance technology the effect of inositol hexaphosphate (IP6) on platelet aggregation and adenosine triphosphate (ATP) release were simultaneously measured in whole ...
I, Vucenik, J J, Podczasy, A M, Shamsuddin   +2 more
openaire   +1 more source

Henley Gate, Ipswich, Suffolk, IP6 9AU

2016
The site was on undulating land in an area of mostly heavy clay soils derived from the underlying Lowestoft Till. A localised deposit of glacial sand and gravel forms a distinct knoll at the east end of the site. A probable Later Bronze Age un-urned cremation was found on relatively high ground overlooking a valley to the north of the site.
openaire   +1 more source

Cancer Inhibition by Inositol Hexaphosphate (IP6) and Inositol: From Laboratory to Clinic [PDF]

Journal of Nutrition, 2003
Inositol hexaphosphate (IP6) is a naturally occurring polyphosphorylated carbohydrate that is present in substantial amounts in almost all plant and mammalian cells. It was recently recognized to possess multiple biological functions. A striking anticancer effect of IP6 was demonstrated in different experimental models.
Ivana, Vucenik, AbulKalam M, Shamsuddin
exaly   +3 more sources

Hierarchical mobility management in IP4/IP6 co-existed networks

2005 International Conference on Wireless Networks, Communications and Mobile Computing, 2005
The new generation of the Internet protocol, IPv6, replaces the IPv4 sooner or later in order to acquire sufficient IP addresses and guarantee the quality of service. The mobile IPv4 has been designed for mobility management in pure IPv4 networks as well as the mobile IPv6 for pure IPv6 networks.
null Li-Wei Huang, null Jen-yi Pan, null Ko-Shung Chen, null Chiao Yu   +3 more
openaire   +1 more source

Mammary tumor inhibition by IP6: a review.

Anticancer research, 2000
While most studies of diet and breast cancer are focused on the role of fat, very few have addressed the effect of fiber. Emerging epidemiological data, and careful review of previous studies point to a negative correlation of breast cancer with high fiber cereal diets.
A M, Shamsuddin, I, Vucenik
openaire   +1 more source

IP6 in treatment of liver cancer. I. IP6 inhibits growth and reverses transformed phenotype in HepG2 human liver cancer cell line.

Anticancer research, 1999
Hepatocellular carcinoma (HCC) is a common tumor world-wide with extremely poor prognosis. Recent studies have shown that inositol hexaphosphate (IP6), a naturally occurring carbohydrate, has novel anti-cancer function in various in vitro and in vivo models.
I, Vucenik, K, Tantivejkul, Z S, Zhang, K E, Cole, I, Saied, A M, Shamsuddin   +5 more
openaire   +1 more source