Results 211 to 220 of about 3,209,210 (281)

Reorganization of Innate Immune Cell Lipid Profiles by Bioinspired Meroterpenoids to Limit Inflammation

open access: yesAdvanced Science, EarlyView.
Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl   +20 more
wiley   +1 more source

Intratumoral Hypoxia Triggers Mitochondrial BHLHE40 ROS Sensing Pathway to Promote Radioresistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Hypoxia triggers a dual mechanism for BHLHE40 upregulation: reactive oxygen species (ROS)‐dependent post‐translational modification and hypoxia‐inducible factor (HIF)‐dependent transcriptional activation. Under hypoxic conditions, mitochondrial BHLHE40 accumulates and senses ROS via cysteine thiol oxidation and disulfide‐linked homodimer formation ...
Jia Liu   +13 more
wiley   +1 more source

Disease-specific tau polymorphs are associated with unique protein networks across proteinopathies. [PDF]

open access: yesEMBO J
Puangmalai N   +10 more
europepmc   +1 more source

Exploration of burnout and imposter phenomenon among dermatology resident doctors in the UK. [PDF]

open access: yesSkin Health Dis
Frimpong-Manso HB   +5 more
europepmc   +1 more source

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