Results 221 to 230 of about 2,688,485 (288)

Comparison of Ebola virus infection routes and resulting disease in animal models. [PDF]

J Virol
Gathright BR, Marzi A.
europepmc   +1 more source

RGS16 Aggravates Hepatic Ischemia‐Reperfusion Injury via Hepatocyte‐Intrinsic Apoptosis/Inflammation & Neutrophil Recruitment/NETosis

Advanced Science, EarlyView.
RGS16 competitively interferes with the YTHDF3–PAN3 complex to prevent CXCL1 mRNA decay during hepatic ischemia‐reperfusion injury. Stabilized CXCL1 strengthens hepatocyte injury, neutrophil recruitment, and NET‐associated inflammation, uncovering how stress‐induced RGS16 converts post‐transcriptional regulation into immune‐mediated liver damage ...
Xinglong Li, Zhanzhi Meng, Hongjun Yu, Yongliang Hua, Zihao Li, Bing Yin, Baolin Qian, Zhongyu Li, Yongzhi Zhou, Zhigang Feng, Shounan Lu, Shanjia Ke, Miaoyu Bai, Yao Fu, Wei Tang, Natalia V. Belosludtseva, Yong Ma   +16 more
wiley   +1 more source

Dual-salt synergistic interfacial polymerization toward loose, negatively charged nanofiltration membranes for safe drinking-water production. [PDF]

RSC Adv
Liu M, Song Y, Zhu L, Chen Y, Yan J, Tang P, Chen C, Geng N.   +7 more
europepmc   +1 more source

Heat Stress Promotes Fibroblast‐Derived WNT5A Secretion Through m6A Modification to Activate Melanogenesis

Advanced Science, EarlyView.
Heat stress promotes WNT5A secretion from fibroblasts via METTL3/YTHDC1‐dependent m6A methylation. Subsequently, WNT5A binds to FZD10 on melanocytes, activating β‐catenin‐driven melanogenesis. ABSTRACT As the impact of global warming continues to intensify, the effects of heat stress on the skin are becoming increasingly evident.
Yuanyuan Wan, Yaqing Wen, Yushan Zhang, Lan Zhang, Jianjian Zhu, Zhen Tang, Ling Jiang, Chuhan Fu, Shu Zhou, Keyi Zhang, Jiangfeng Huang, Li Lei, Jing Chen, Qinghai Zeng   +13 more
wiley   +1 more source

Brivaracetam in Combination with Midazolam and Ketamine Reduces Soman-Induced Seizure and Neurodegeneration in Rats. [PDF]

Neurol Int
Lumley LA, Steier HG, Orta SY, Nguyen DA, Stone MF, Schultz CR, Niquet J, de Araujo Furtado M, Wasterlain CG.   +8 more
europepmc   +1 more source

Deltacoronavirus Modulates circRNA cGLIS3 Metabolism to Evade Host Antiviral Response

Advanced Science, EarlyView.
This study reveals that both deltacoronavirus nucleocapsid protein and host RNA binding protein IGF2BP2 promote circular RNA GLIS3 (cGLIS3) biogenesis by binding to GLIS3 pre‐mRNA. The m6A modification‐mediated cGLIS3‐IGF2BP2 interaction weakens RNase L‐mediated degradation of cGLIS3 while facilitates a ubiquitin‐dependent degradation of IGF2BP2, thus ...
Liuyang Du, Liping Wang, Sujing Diao, Juan Li, Lei Zhao, Yan Yan, Haimin Li, Weiren Dong, Wei Wu, Jinyan Gu, Jiyong Zhou   +10 more
wiley   +1 more source

The Therapeutic Potential of Stem Cell Therapy for Doxorubicin-Induced Cardiotoxicity: A Narrative Review. [PDF]

Health Sci Rep
Mirzaei A, Rezaei P, Vafa RG, Jahani S, Arefnezhad R, Fatemian H, Nikoo MH, Sahebkar A, Rezaei-Tazangi F.   +8 more
europepmc   +1 more source

T cell-mediated protection against lethal SARS-CoV-2 challenge by a synthetic long peptide vaccine targeting conserved CD4+ and CD8+ T cell epitopes

Gracht ETvd, Pardieck IN, Duikeren Sv, Rijn Pv, Veerkamp DM, de Graaf JF, Kwappenberg K, Kamerling IM, Kruithof AC, Plas JLvd, Linger ME, Horst JRB, Myeni SK, Krebber W, Hooftman L, Beenakker TJ, Arens R, Melief CJ, Wiekmeijer A.   +18 more
europepmc   +1 more source

Artificial intelligence, intellectual property, and human rights: mapping the legal landscape in European health systems. [PDF]

Npj Health Syst
van Kessel R, Schmidt J, van Kolfschooten H, Feudo S, Young K, Valtere L, Minssen T, Mossialos E.   +7 more
europepmc   +1 more source

Sex-based differences in mumps immunity after a third dose of measles-mumps-rubella vaccine. [PDF]

Vaccine
Quach HQ, Ratishvili T, Haralambieva IH, Ovsyannikova IG, Poland GA, Kennedy RB.   +5 more
europepmc   +1 more source