Results 41 to 50 of about 6,948 (137)

Cancer outcomes among Parkinson's disease patients with leucine rich repeat kinase 2 mutations, idiopathic Parkinson's disease patients, and nonaffected controls [PDF]

open access: yes, 2019
BACKGROUND: Increased cancer risk has been reported in Parkinson's disease (PD) patients carrying the leucine rich repeat kinase 2 (LRRK2) G2019S mutation (LRRK2-PD) in comparison with idiopathic PD (IPD). It is unclear whether the elevated risk would
Aasly, Jan   +24 more
core   +1 more source

Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program [PDF]

open access: yes, 2017
Biomarkers for Parkinson's disease (PD) diagnosis, prognostication and clinical trial cohort selection are an urgent need. While many promising markers have been discovered through the National Institute of Neurological Disorders and Stroke Parkinson's ...
Albin, Roger   +25 more
core   +1 more source

Studying the effect of the psychosocial work environment on risk of ill-health: towards a more comprehensive assessment of working conditions

open access: yesScandinavian Journal of Work, Environment & Health, 2012
The Nordic countries have a long tradition of research studying the impact of the psychosocial work environment on health (1, 2). Fittingly, the Scandinavian Journal of Work, Environment and Health has been a key place for the presentation and discussion
Reiner Rugulies
doaj   +1 more source

JAM: A Scalable Bayesian Framework for Joint Analysis of Marginal SNP Effects. [PDF]

open access: yes, 2016
Recently, large scale genome-wide association study (GWAS) meta-analyses have boosted the number of known signals for some traits into the tens and hundreds. Typically, however, variants are only analysed one-at-a-time.
Conti, David V   +2 more
core   +1 more source

Train Wrecks and Track Attacks: An Analysis of Attempts by Terrorists and Other Extremists to Derail Trains or Disrupt Rail Transportation [PDF]

open access: yes, 2018
Attempts to sabotage rails and deliberately derail passenger trains have a long history in conventional and guerrilla warfare as well as during some particularly bitter labor disputes in the past.
Butterworth, Bruce R.   +1 more
core   +1 more source

ZikaPLAN: addressing the knowledge gaps and working towards a research preparedness network in the Americas. [PDF]

open access: yes, 2019
Zika Preparedness Latin American Network (ZikaPLAN) is a research consortium funded by the European Commission to address the research gaps in combating Zika and to establish a sustainable network with research capacity building in the Americas.
Alessandro Sette   +53 more
core   +9 more sources

Back-calculating the incidence of infection of leprosy in a Bayesian framework [PDF]

open access: yes, 2015
Background: The number of new leprosy cases reported annually is falling worldwide, but remains relatively high in some populations. Because of the long and variable periods between infection, onset of disease, and diagnosis, the recently detected cases
Crump, Ron E., Medley, Graham
core   +3 more sources

The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1 [PDF]

open access: yes, 2017
Serotype 1 is one of the most common causes of pneumococcal disease worldwide. Pneumococcal protein vaccines are currently being developed as an alternate intervention strategy to pneumococcal conjugate vaccines.
Adzhubei   +48 more
core   +6 more sources

Sustainable Strategic Urban Planning: Methodology for Urban Renovation At District Level [PDF]

open access: yes, 2017
Sustainable urban renovation is characterized by multiple factors (e.g. technical, socio-economic, environmental and ethical perspectives), different spatial scales and a number of administrative structures that should address the evaluation of ...
Arrizabalaga, Eneko   +3 more
core   +1 more source

Individual patient data meta-analysis of trials investigating the effectiveness of intra-articular glucocorticoid injections in patients with knee or hip osteoarthritis:an OA Trial Bank protocol for a systematic review [PDF]

open access: yes, 2013
BACKGROUND: Based on small to moderate effect sizes for the wide range of symptomatic treatments in osteoarthritis (OA), and on the heterogeneity of OA patients, treatment guidelines for OA have stressed the need for research on clinical predictors of ...
Bierma-Zeinstra, Sita M A   +7 more
core   +1 more source

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