Results 131 to 140 of about 88,697 (303)

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

The CIRM iPSC repository

Stem Cell Research, 2020
Stephen S. Lin, Susan DeLaura, Eugenia M. Jones   +2 more
openaire   +3 more sources

Magnetoelectric BaTiO3/CoFe2O4 Thin‐Film Meshes for Neuronal Differentiation

Advanced Science, EarlyView.
We engineer an epitaxial BaTiO3/CoFe2O4 magnetoelectric mesh that overcomes boundary‐induced mechanical clamping. Progressively reducing the mechanical constraint, from substrate‐clamped to PDMS‐transferred and ultimately freestanding, enhances magnetic‐to‐electric transduction and strengthens magnetoelectric coupling.
Mathieu Mirjolet, Hao Ye, Abderrahim Lahlahi Attalhaoui, Donghoon Kim, Vitaly Pustovalov, Elric Zhang, Marc Tudela‐Pi, Bastian Gebauer, Juan Bautista Carda Castelló, Anton Guimerà‐Brunet, Josep Puigmartí‐Luis, Xiang‐Zhong Chen, Minsoo Kim, Salvador Pané   +13 more
wiley   +1 more source

Stepwise combined cell transplantation using mesenchymal stem cells and induced pluripotent stem cell-derived motor neuron progenitor cells in spinal cord injury

Stem Cell Research & Therapy
Background Spinal cord injury (SCI) is an intractable neurological disease in which functions cannot be permanently restored due to nerve damage. Stem cell therapy is a promising strategy for neuroregeneration after SCI. However, experimental evidence of
Jang-Woon Kim, Juryun Kim, Hyunkyung Mo, Heeju Han, Yeri Alice Rim, Ji Hyeon Ju   +5 more
doaj   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Expression of TRPV2 proteins in IMR90-iPSC-ECs and HGPS-iPSC-ECs.

, 2014
(A and B), representative images (A) and data summary (B) of TRPV2 protein expression in IMR90- and HGPS-iPSC-ECs.
Nelson L. Tang (515416), Chun-Yin Lo (515412), Xiaoqiang Yao (171244), Hung-Fat Tse (351982), Yung-Wui Tjong (515413), Jenny Chung-Yee Ho (515414), Chung-Wah Siu (351983), Shan Yu (219591), Sin-Ying Cheung (515415)   +8 more
core   +1 more source

Gate Metal‐Driven Sensing and Memory Bifunctionality in Intrinsically Stretchable Organic Electrochemical Transistors for Soft Neuromorphic Systems

Advanced Science, EarlyView.
Intrinsically stretchable OECTs enable bifunctional operations via gate engineering. Polarizable Ag/AgCl gates provide volatile sensing, while Au gates enable non‐volatile memory. The SEBS‐blended channel maintains performance under strain, supporting reliable signal transduction.
Jiyong Yoon, Jaepyo Jang, Hyunjin Jung, Duhwan Seong, Daeun Kim, Yewon Jeon, Ja Hoon Koo, Sang Min Won, Donghee Son   +8 more
wiley   +1 more source

Makespan - NASA Ames iPSC/860 Dataset.

, 2016
Makespan - NASA Ames iPSC/860 Dataset.
Mohammed Abdullahi (846140), Md Asri Ngadi (846138)   +1 more
core   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Improving High‐Temperature Operational Stability of Inverted Perovskite Solar Cells Through MXene Heat‐Dissipating Layers

Advanced Science, EarlyView.
MeO‐2PACz‐functionalized MXene nanosheets create a thermally conductive buried interface in inverted perovskite solar cells. The interface improves heat spreading, suppresses defects and ion migration, and strengthens charge extraction, extending T80 at 65°C from 141 to 687 h while maintaining competitive efficiency.
Masoud Karimipour, Nil Monrós Oliveras, Zhenchuan Tian, Timm Swoboda, Francesco Salutari, Marianna Sledzinska, Maria Chiara Spadaro, Kenedy Tabah Tanko, Javier Rodríguez‐Viejo, Jordi Arbiol, Tiankai Zhang, Feng Gao, Monica Lira‐Cantu   +12 more
wiley   +1 more source