Results 281 to 290 of about 116,955 (355)

CX-5461 and doxorubicin activate a shared DNA damage-associated transcriptional response in human cardiomyocytes. [PDF]

G3 (Bethesda)
Paul S, Gutiérrez JA, Bogar AR, Matthews ER, Ward MC.   +4 more
europepmc   +1 more source

Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease [PDF]

, 2018
et al,, Jiang, Xuntian, Ory, Daniel S
core   +1 more source

Caracterización clínica y análisis de exoma clínico, generación y edición genética de células madre pluripotentes inducidas (iPSC) de pacientes con distrofias hereditarias de la retina asociadas al gen PROM1

Kevin Louis Puertas Neyra
openalex   +1 more source

Most L1CAM is not associated with extracellular vesicles in human biofluids and iPSC–derived neurons [PDF]

Vaibhavi Kadam, Madeleine Wacker, Patrick Oeckl, Milena Korneck, Benjamin Dannenmann, Julia Skokowa, Stefan Hauser, Markus Otto, Matthis Synofzik, David Mengel   +9 more
openalex   +1 more source

Engineering Smart Biomaterial Interfaces for iPSC-CM Maturation: A Biophysical and Metabolic Reprogramming Approach to Regenerative Cardiac Medicine. [PDF]

Int J Mol Sci
Shahannaz DC, Sugiura T.
europepmc   +1 more source

Synaptic vesicle characterization of iPSC-derived dopaminergic neurons provides insight into distinct secretory vesicle pools [PDF]

Kenshiro Fujise, Martin Rosenfeld, Nisha Mohd Rafiq   +2 more
openalex   +1 more source

Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models

Pediatric Discovery, EarlyView.
ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou, Christopher L.‐H. Huang, Ying Yang, Yanmin Zhang   +3 more
wiley   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Unbiased data-driven analysis of five amyloid-beta peptides for biomarker investigations in familial Alzheimer's disease. [PDF]

Brain Commun
Llorente-Saguer I, Gabriele R, Bradshaw TY, Leckey CA, Belder CRS, Chávez-Gutiérrez L, de Silva R, Fox NC, Wray S, Oxtoby NP, Arber C.   +10 more
europepmc   +1 more source