Results 41 to 50 of about 822,046 (302)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

The fourth spectrum of iridium (Ir IV) [PDF]

Atomic Data and Nuclear Data Tables, 2016
Abstract The spectrum of three times ionized iridium, Ir IV, was investigated in the 650–2045 A wavelength region. The analysis has led to the determination of the 5 d 6 , 5 d 5 6 s and 5 d 5 6 p configurations.
Vladimir I. Azarov, Robert R. Gayasov
openaire   +1 more source

Do scale-invariant fluctuations imply the breaking of de Sitter invariance?

, 2012
The quantization of the massless minimally coupled (mmc) scalar field in de Sitter spacetime is known to be a non-trivial problem due to the appearance of strong infrared (IR) effects.
Youssef, Ahmed
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Using mid infrared to perform investigations beyond the diffraction limits of microcristalline pathologies: advantages and limitation of Optical PhotoThermal IR spectroscopy

Comptes Rendus. Chimie, 2022
Understanding the physico-chemistry related to cristalline pathologies constitutes a challenge in several medical specialities such as nephrology, dermatology or oncology.
Bazin, Dominique, Bouderlique, Elise, Tang, Ellie, Daudon, Michel, Haymann, Jean-Philippe, Frochot, Vincent, Letavernier, Emmanuel, Van de Perre, Els, Williams, James C. Jr., Lingeman, James E., Borondics, Ferenc   +10 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Synthesis, crystal structure and properties of poly[(μ-2-methylpyridine N-oxide-κ2O:O)bis(μ-thiocyanato-κ2N:S)cobalt(II)]

Acta Crystallographica Section E: Crystallographic Communications
The title compound, [Co(NCS)2(C6H7NO)]n or Co(NCS)2(2-methylpyridine N-oxide), was prepared by the reaction of Co(NCS)2 and 2-methylpyridine N-oxide in methanol. All crystals obtained by this procedure show reticular pseudo-merohedric twinning, but after
Christian Näther, Inke Jess
doaj   +1 more source

Cosmological parameters in the noncommutative inflation

, 2004
We investigate how the uncertainty of noncommutative spacetime could explain the WMAP data. For this purpose, the spectrum is divided into the IR and UV region.
Bardeen, Bennett, Brandenberger, Brandenberger, Bridle, Cai, Calcagni, Fukuma, Fukuma, Fukuma, Huang, Huang, Huang, Kim, Kim, Kim, Kim, Kodama, Li, Liddle, Lizzi, Lukash, Lukash, Martin, Martin, Mukhanov, Mukhanov, Mukherjee, Peiris, Polchinski, Sasaki, Schwarz, Spergel, Stewart, Stewart, Stewart, Tsujikawa, Yoneya, Yoneya, Yun Soo Myung   +39 more
core   +3 more sources

Aerosol particle molecular spectroscopy [PDF]

, 1985
The molecular spectroscopy of a solution particle by structure resonance modulation spectroscopy is discussed [S. Arnold and A. B. Pluchino, "Infrared Spectrum of a Single Aerosol Particle by Photothermal Modulation of Structure Resonances," Appl.
Arnold, S., Murphy, E. K., Sageev, G.
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source