Results 41 to 50 of about 10,737 (256)

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

INSTRUCTOR'S VISUAL ARTS EDUCATION: A CASE STUDY

Trakya University Journal of Social Sciences, 2019
The widespread use of visual arts in fields such as business, engineering, finance, applied sciences, industrial design has also increased the disciplinary academic work on this association.
Medine Irak
doaj   +1 more source

ZnO Nanowires for Ultraviolet Detection: Recent Developments, Challenges, and Future Outlook

Advanced Electronic Materials, EarlyView.
This work provides a comprehensive review of Zinc Oxide (ZnO) nanowires for high‐performance ultraviolet (UV) photodetection. By analyzing unique device physics and various detector architectures, it unveils strategies to overcome current performance limitations regarding speed and sensitivity.
Ala K. Jehad, Salih Alper Akalin, Mustafa Erol, Yavuz Ozturk, Metin Yurddaskal   +4 more
wiley   +1 more source

Weather Attention in Online Discourse and Price Uncertainty in Agricultural Futures Markets

Agribusiness, EarlyView.
ABSTRACT Weather is a central determinant of production risk in agricultural markets, but markets respond not only to weather conditions themselves, but also to how those conditions are noticed, framed, and interpreted in public discourse. In this setting, real‐time online weather discussions may shape price uncertainty by influencing how market ...
Mario A. Ortez, Olga Isengildina Massa, Michael Liam Smith, Nicole Olynk Widmar   +3 more
wiley   +1 more source

MiR‐146a‐5p Suppresses M1 Polarization of Tumor‐Associated Macrophages via IRAK1/NF‐κB Signaling in Colorectal Polyps

Annals of Gastroenterological Surgery, EarlyView.
MiR‐146a‐5p is downregulated in colorectal polyps, leading to IRAK1 upregulation and NF‐κB activation, which promotes M1 macrophage polarization and inflammation. Overexpression of miR‐146a‐5p suppresses IRAK1/NF‐κB signaling, reduces M1 polarization, and alleviates inflammatory responses.
Peng Song, Lianhui Wu, Huabin Qiu, Lei Luo, Jianzhao Qiu, Shuping Xiao, Jincai He   +6 more
wiley   +1 more source

Redistributive land reforms, agricultural productivity, and structural change: New cross‐national evidence

American Journal of Agricultural Economics, EarlyView.
Abstract Large‐scale land reforms constitute a substantial redistribution of wealth and reallocation of agricultural land, which is a major form of asset and production input in developing countries. While land redistribution (from the rich to the poor) remains a highly controversial issue, extensive evidence on its effect is limited.
Devashish Mitra, Abdulaziz B. Shifa, Lan Anh Tong, Mehmet A. Ulubasoglu   +3 more
wiley   +1 more source

The IRAK-M death domain: a tale of three surfaces

Frontiers in Molecular Biosciences
The anti-inflammatory interleukin-1 receptor associated kinase-M (IRAK-M) is a negative regulator of MyD88/IRAK-4/IRAK-1 signaling. However, IRAK-M has also been reported to activate NF-κB through the MyD88/IRAK-4/IRAK-M myddosome in a MEKK-3 dependent ...
Berke Gürkan, Berke Gürkan, Hessel Poelman, Hessel Poelman, Liza Pereverzeva, Liza Pereverzeva, Danielle Kruijswijk, Danielle Kruijswijk, Alex F. de Vos, Alex F. de Vos, Anouk G. Groenen, Anouk G. Groenen, Edgar E. Nollet, Edgar E. Nollet, Kanin Wichapong, Esther Lutgens, Tom van der Poll, Tom van der Poll, Tom van der Poll, Jiangfeng Du, W. Joost Wiersinga, W. Joost Wiersinga, W. Joost Wiersinga, Gerry A. F. Nicolaes, Gerry A. F. Nicolaes, Cornelis van ‘t Veer, Cornelis van ‘t Veer   +26 more
doaj   +1 more source

Phylogenomic insights into the genus Tulipa (Liliaceae): Taxonomy, evolution, and biogeography

American Journal of Botany, EarlyView.
Abstract Premise Tulips are one of the best‐known geophytes, but their taxonomy remains convoluted and their evolutionary history poorly understood. Here, we used plastid genomes to identify some issues with current classification, understand the diversification history of the genus, and identify potential species linked to historical cultivation ...
Brett Wilson, Maarten J. M. Christenhusz, Nathanael Walker‐Hale, Natalya Beshko, Mariyo Boboev, Colin Clubbe, Davron Dekhkonov, Aibek Dolotbakov, Mehmet Firat, Thomas Freeth, Sjaak de Groot, Avni Hajdari, Georgy A. Lazkov, Ormon Sultangaziev, Komiljon S. Tojibaev, Ben J. M. Zonneveld, Kaiyrkul T. Shalpykov, Samuel F. Brockington   +17 more
wiley   +1 more source

MicroRNA-146a-5p Mediates High Glucose-Induced Endothelial Inflammation via Targeting Interleukin-1 Receptor-Associated Kinase 1 Expression

Frontiers in Physiology, 2017
Background and Aims: Interleukin-1 receptor-associated kinase-1 (IRAK-1) is critical for mediating toll-like receptor and interleukin-1 receptor signaling.
Wan-Yu Lo, Ching-Tien Peng, Ching-Tien Peng, Huang-Joe Wang, Huang-Joe Wang, Huang-Joe Wang   +5 more
doaj   +1 more source

The psychosocial toll of Dublin III on asylum seekers in the Netherlands

American Journal of Community Psychology, EarlyView.
Abstract The Dublin III Regulation determines which EU Member State is responsible for examining asylum claims, but its implementation carries significant consequences for those subjected to it. This study examines how Dublin III, as implemented in the Netherlands, affects asylum seekers' psychosocial wellbeing using Silove′s Adaptation and Development
Imen El Amouri
wiley   +1 more source