Results 61 to 70 of about 492,305 (300)
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Nature Communications, 2021 Inflammatory bowel disease is caused by chronic inflammation of the gastrointestinal tract and disturbed immune responses. Here the authors present examination of Cortistatin analogues that display enhanced half-life stability whilst maintaining ...
Álvaro Rol +14 more
doaj +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
An Education Program for Thai IRB Staffs: “Modern IRB Officersâ€
Siriraj Medical Journal, 2020 Objective: Standard operating procedures and education for Institutional Review Board (IRB) staff are important issues and will contribute to their competency and effectiveness in working.
Sriwimon Manochiopinig +2 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
, 2016 This contains the IRB information used for the study.
Delora Everett, Dana C. Leighton
core +4 more sources
Journal of Urban Mathematics Education, 2023 Our research institutions in the US do an excellent job of both protecting participants and allowing researchers to ask and answer new questions. When a researcher embarks on a journey to examine educational spaces in another country, how does and IRB ...
Natalia Bailey
doaj
THE BNIP3 TRIAD: MITOCHONDRIA, LYSOSOMES AND INFLAMMATION IN HEALTHY MUSCLE AGING
Autophagy Reports, 2022 During aging, skeletal muscle undergoes a loss of mass, strength and function, encompassed in the biological process termed sarcopenia. Given demographic aging, it is essential to comprehend the molecular determinants resulting in age-related sarcopenia.
Andrea Irazoki +2 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source
IRB Research Proposal: K01 [PDF]
, 2014 There is a critical need to understand why there is less than optimal uptake of the HPV vaccine among Hispanic girls along the Texas-Mexico border, despite the high cervical cancer incidence and mortality rates for Hispanic women in this area.
Latino Research Institute +1 more
core +1 more source