Results 61 to 70 of about 459,568 (307)
IRBs, Conflict and Liability: Will We See IRBs in Court? Or is it when? [PDF]
Clinical Medicine & Research, 2003 The entire human research infrastructure is under intense and increasing financial pressure. These pressures may have been responsible for several errors in judgment by those responsible for managing human research and protecting human subjects. The result of these errors has been some terrible accidents, some of which have cost the lives of human ...
openaire +2 more sources
Compound Heterozygote Friedreich Ataxia Patients With Covert Proximal FXN Gene Deletions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We present Friedreich ataxia patients with frataxin gene deletions. Data and records were collected at the Children's Hospital of Philadelphia from patients enrolled in the FACOMS natural history study. Patients with proximal deletions initially diagnosed with only one GAA expanded allele had more severe disease than their homozygous expansion
Michael P. Lazaropoulos +5 more
wiley +1 more source
Nature CommunicationsSomatic cells can transform into tumors due to mutations, and the tumors further evolve towards increased aggressiveness and therapy resistance. We develop DiffInvex, a framework for identifying changes in selection acting on individual genes in somatic ...
Ahmed Khalil, Fran Supek
doaj +1 more source
, 1990 SIGLEAvailable from Informationszentrum Raum und Bau (IRB) der Fraunhofer-Gesellschaft, Stuttgart (DE) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Informationszentrum Raum und Bau (IRB), Stuttgart (Germany)
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Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Educational research--to IRB, or not to IRB?
Family medicine, 2005 Miser, William F.
openaire +2 more sources
, 1989 Available from Informationszentrum Raum und Bau der Fraunhofer-Gesellschaft (IRB), Stuttgart (DE) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Informationszentrum Raum und Bau (IRB), Stuttgart (Germany)
core
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Institutional Review Board (IRB) roster
, 2016 Wichita State University Institutional Review Board (IRB) roster including names, departments, and committee ...
Institutional Review Board (IRB) +1 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source