Results 81 to 90 of about 492,305 (300)
IRBs, Conflict and Liability: Will We See IRBs in Court? Or is it when? [PDF]
Clinical Medicine & Research, 2003 The entire human research infrastructure is under intense and increasing financial pressure. These pressures may have been responsible for several errors in judgment by those responsible for managing human research and protecting human subjects. The result of these errors has been some terrible accidents, some of which have cost the lives of human ...
openaire +2 more sources
, 1990 SIGLEAvailable from Informationszentrum Raum und Bau (IRB) der Fraunhofer-Gesellschaft, Stuttgart (DE) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Informationszentrum Raum und Bau (IRB), Stuttgart (Germany)
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini +12 more
wiley +1 more source
Execution of SOP: Principal Investigator (PI)/Study Personnel, IRB
, 2014 To describe Institutional Review Board (IRB) review of data and safety monitoring plan(s) (DSMP) to ensure adequate protection is in place for subjects GENERAL DESCRIPTION Investigators develop data and safety monitoring plans as a mechanism for assuring
Nonmedical Irb
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Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong +10 more
wiley +1 more source
Institutional Review Board (IRB) roster
, 2016 Wichita State University Institutional Review Board (IRB) roster including names, departments, and committee ...
Institutional Review Board (IRB) +1 more
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Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi +6 more
wiley +1 more source
, 1989 Available from Informationszentrum Raum und Bau der Fraunhofer-Gesellschaft (IRB), Stuttgart (DE) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Informationszentrum Raum und Bau (IRB), Stuttgart (Germany)
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem +9 more
wiley +1 more source