Results 91 to 100 of about 492,305 (300)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Choroid plexus volume (CPV) has been proposed as a neuro‐immunological marker of multiple sclerosis (MS), but its relevance in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD) remains uncertain. We analyzed CPV in 43 individuals with MOGAD, 48 with MS, and 44 healthy controls using a Bayesian Gaussian mixture modeling ...
Jae‐Won Hyun +4 more
wiley +1 more source
Stereochemically-aware bioactivity descriptors for uncharacterized chemical compounds
Journal of CheminformaticsStereochemistry plays a fundamental role in pharmacology. Here, we systematically investigate the relationship between stereoisomerism and bioactivity on over 1 M compounds, finding that a very significant fraction (~ 40%) of spatial isomer pairs show ...
Arnau Comajuncosa-Creus +4 more
doaj +1 more source
Solare Stromerzeugung im Bauwesen Grundlagen, Anwendung
, 1989 Available from Informationszentrum Raum und Bau der Fraunhofer-Gesellschaft (IRB), Stuttgart (DE) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLE2.
Schloz, T. (comp.) +1 more
core
Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad +22 more
wiley +1 more source
The DNA dialect: a comprehensive guide to pretrained genomic language models
Molecular Systems BiologyFollowing their success in natural language processing and protein biology, pretrained large language models have started appearing in genomics in large numbers.
Marcell Veiner, Fran Supek
doaj +1 more source
, 1986 Available from Informationszentrum Raum und Bau (IRB), Stuttgart (DE) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Jurnik, A. +1 more
core
Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son +3 more
wiley +1 more source
, 1987 Available from Informationszentrum Raum und Bau (IRB), Stuttgart (DE) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische ...
Informationszentrum Raum und Bau (IRB), Stuttgart (Germany) +1 more
core
White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram +3 more
wiley +1 more source
Phenotypic AI-based design of cell-specific small molecule cytotoxics
Communications ChemistryArtificial intelligence is transforming drug discovery by enabling exploration of vast chemical spaces and the design of new molecules with tailored properties.
Gema Rojas-Granado +6 more
doaj +1 more source