Results 91 to 100 of about 78,348 (310)
Metal Coatings for Electrocatalytic Applications: Towards a Safe and Sustainable by Design Approach
ProceedingsSeveral attempts have been made to replace the critical raw material platinum (Pt) with other metals, mainly focusing on its functional performance, while safety and sustainability criteria are often overlooked.
Konstantina-Roxani Chatzipanagiotou +3 more
doaj +1 more source
Proteins Enhancing IRES-Mediated Translation
, 2021 Certain RNAs are proposed to have an internal ribosome entry site (IRES) in their 5’ untranslated region (UTR). RNAs with an IRES include the encephalomyocarditis virus (EMCV), poliovirus (PV), hepatitis C virus (HCV), cricket paralysis virus (CrPV) and ...
Owusu Ampaw, Emmanuella
core +1 more source
Advanced Science, EarlyView.ABHD17C‐mediated depalmitoylation of BCL6B at Cys442 blocks its nuclear import and triggers ubiquitin‐dependent degradation, attenuating transcriptional repression of the anti‐phagocytic signal CD24. This mechanism enables pancreatic cancer cells to evade macrophage phagocytosis and fosters an immunosuppressive microenvironment.
Yalu Zhang +9 more
wiley +1 more source
Journal of Experimental and Theoretical AnalysesAccording to the International Diabetes Federation, approximately 537 million adults suffered from diabetes in 2021, a number that is projected to rise to 783 million by 2045.
Konstantina-Roxani Chatzipanagiotou +4 more
doaj +1 more source
Rapporti tra utilizzazione agricola e tutela nelle aree a parco naturale o soggette a vincoli protezionistici in Piemonte [PDF]
, 1988 - Le condizioni di parco e l'agricoltura #7- Le conseguenze economiche nelle aree a parco #31- Conclusioni ...
Ires
core
Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
ToxicsPharmaceuticals are increasingly recognized as contaminants of emerging concern, yet monitoring strategies often do not reflect actual consumption patterns or ecological risk.
Konstantina-Roxani Chatzipanagiotou +4 more
doaj +1 more source
Rapporto preliminare per il piano di sviluppo della val Pellice [PDF]
, 1972 - Indice #3- Studio preliminare e piano di sviluppo socio-economico per le aree montane #11- Le condizioni generali del territorio #49- Situazione dinamica socio-economica #53- I servizi sociali #225- L'assetto ecologico e la copertura forestale #287 ...
IRES
core
CCL3 and IL‐7 Synergistically Enhance CAR‐T Efficacy in Solid Tumors
Advanced Science, EarlyView.Synergistic delivery of CCL3 and IL‐7 by CAR‐T cells overcomes the immunosuppressive tumor microenvironment by enhancing cell infiltration, survival, and local immune reprogramming. This also establishes positive feedback that amplifies anti‐tumor activity and memory responses in both CAR‐T and endogenous T cells, presenting a robust therapeutic ...
Huanpeng Chen +12 more
wiley +1 more source
Advanced Science, EarlyView.Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li +13 more
wiley +1 more source