Results 111 to 120 of about 60,229 (263)

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

open access: yesHepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam   +10 more
wiley   +1 more source

Shifting IRES versus Cap-initiated translation during homeostatic stem cell differentiation and stress. [PDF]

open access: yesSci Adv
Mazzola MC   +27 more
europepmc   +1 more source

Animal empathy reconsidered: a multidimensional profile account

open access: yesBiological Reviews, EarlyView.
ABSTRACT Empathy is the glue that holds societies together and yet several fundamental questions about empathy persist. What is empathy (the definitional question)? Is it uniquely human and, if not, which nonhuman animals possess empathy (the distribution question)? Which type or quality of empathy is realized in different species (the quality question)
Albert Newen   +5 more
wiley   +1 more source

The Degradation of Access‐Based Business Models: Customer Misbehavior and Shared Mobility

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Access‐based services are considered one of the strategies to embed sustainability in business models. Yet, because the evolution of these business models has been overlooked, we do not know whether their promise to create triple value is sustained.
Andres Camacho, Carmen Valor
wiley   +1 more source

Ikimokyklinio ir priešmokyklinio ugdymo pokyčiai: ir nerimas, ir džiaugsmas

open access: yes, 2020
Nuo 2023 m. pagerės sąlygos socialinės rizikos šeimoms auginančioms priešmokyklinio amžiaus vaikus (5-6 m.), nes savivaldybės įpareigotos užtikrinti ikimokyklinį ugdymą visiems vaikams. Dalis savivaldybių šią žinią sutiko su nerimu ir nepasitenkinimu. Gali kilti klausimas apie kokį vaikų skaičių, padidinančių priešmokyklinukų gretas, kalbame.
openaire   +1 more source

Default Effect in ESG Investment: When a Recommendation Goes a Long Way

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Individual investors display a positive attitude toward ESG investments but typically fail to act upon it. We report results from a preregistered online experiment testing a default option on 1050 US investors examining the mechanisms driving the effectiveness of default options in promoting ESG investments.
Sai Sravanthi Ramadugula   +2 more
wiley   +1 more source

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