Results 101 to 110 of about 51,891 (312)
Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen +7 more
wiley +1 more source
Archives of Pathology & Laboratory Medicine, 2008 Abstract The iris is the least common site of primary uveal melanoma. The prognosis of iris melanoma is better than that of melanoma of the ciliary body and choroid, but the reason for this difference is unclear. One possible explanation is that iris melanoma is smaller than its posterior segment counterparts at the time of diagnosis.
Evita, Henderson, Curtis E, Margo
openaire +2 more sources
International Journal of Cancer, EarlyView.Pre‐treatment DPYD and UGT1A1 genotyping is increasingly used to prevent fluoropyrimidine‐ and irinotecan‐related toxicity, but variant‐specific real‐world effects remain unclear. In an unselected cohort of cancer patients with actionable genotypes, genotype‐driven dosing improved safety while preserving treatment exposure in high‐risk DPYD c.1905+1G>A
Martina Gambron +12 more
wiley +1 more source
Comparison of GPS TEC With Modelled Values from IRI 2016 and IRI-PLAS Over Istanbul, Turkey
, 2018 The Total Electron Content (TEC) prediction performances of the empirical IRI model and IRI-PLAS model were investigated by comparing the GPS-based TEC values provided by the IONOLAB group.
Atıcı, Ramazan
core +1 more source
, 2020 El principio de jurisdicción universal y su encrucijada. ¿Utopía o el Mundo Real? Josefina Buscetti y Mayra Scaramutti Miembros del Departamento de Derecho Internacional del Instituto de Relaciones Internacionales | UNLP. El sistema de solución de
Lecturas
core +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Scientific ReportsCardiac ischemic preconditioning (Pre) reduces cardiac ischemia–reperfusion injury (IRI) by stimulating opioid receptors. Chronic use of opioids can alter the signaling pathways. We investigated the effects of chronic methadone use on IRI and Pre.
Mahboobeh Yeganeh-Hajahmadi +3 more
doaj +1 more source
Online, automatic, ionospheric maps: IRI-PLAS-MAP
, 2015 Global and regional behavior of the ionosphere is an important component of space weather. The peak height and critical frequency of ionospheric layer for the maximum ionization, namely, hmF2 and foF2, and the total number of electrons on a ray path ...
ARIKAN, FATMA GÜLAY +5 more
core +1 more source
The Endothelial CXCR Family in Vascular Health and Disease
iNew Medicine, EarlyView.ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu +4 more
wiley +1 more source
Splenectomy modulates intrarenal B cell differentiation and impairs repair of post-ischemic kidney
Frontiers in ImmunologyIntroductionLymphocytes are known to regulate kidney repair after ischemia-reperfusion injury (IRI). Splenectomy has been proposed as a preconditioning protocol for high-risk kidney transplantation and has been suggested to affect IRI outcomes.
Kyungho Lee +8 more
doaj +1 more source