Results 31 to 40 of about 2,881 (198)

Megalocytiviruses

open access: yesViruses, 2012
The genus Megalocytivirus, represented by red sea bream iridovirus (RSIV), the first identified and one of the best characterized megalocytiviruses, Infectious spleen and kidney necrosis virus (ISKNV), the type species of the genus, and numerous other ...
Kazuhiro Nakajima, Jun Kurita
doaj   +1 more source

Characterization of a ranavirus inhibitor of the antiviral protein kinase PKR [PDF]

open access: yes, 2011
Background Ranaviruses (family Iridoviridae) are important pathogens of lower vertebrates. However, little is known about how they circumvent the immune response of their hosts.
Stefan Rothenburg   +2 more
core   +2 more sources

Extension of the viral ecology in humans using viral profile hidden Markov models. [PDF]

open access: yesPLoS ONE, 2018
When human samples are sequenced, many assembled contigs are "unknown", as conventional alignments find no similarity to known sequences. Hidden Markov models (HMM) exploit the positions of specific nucleotides in protein-encoding codons in various ...
Zurab Bzhalava   +2 more
doaj   +1 more source

Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential [PDF]

open access: yesOpen Biology, 2020
Viral macrodomains possess the ability to counteract host ADP-ribosylation, a post-translational modification implicated in the creation of an antiviral environment via immune response regulation.
Johannes Gregor Matthias Rack   +5 more
doaj   +1 more source

Rana grylio virus 43R encodes an envelope protein involved in virus entry [PDF]

open access: yes, 2018
Rana grylio virus (RGV), a member of genus Ranavirus in the family Iridoviridae, is a viral pathogen infecting aquatic animal. RGV 43R has homologues only in Ranavirus and contains a transmembrane (TM) domain, but its role in RGV infection is unknown. In
Gao, Xiao-Chan   +2 more
core   +1 more source

Megalocytivirus Infections in Fish, with Emphasis on Ornamental Species

open access: yesEDIS, 2013
This document is about megalocytiviruses, a group of fish viruses in the family Iridoviridae, which cause systemic infections in various freshwater and marine fish species1.
Roy Yanong, Thomas B. Waltzek
doaj   +1 more source

A broadly applicable method to characterize large DNA viruses and adenoviruses based on the DNA polymerase gene [PDF]

open access: yes, 2006
Background Many viral pathogens are poorly characterized, are difficult to culture or reagents are lacking for confirmatory diagnoses. We have developed and tested a robust assay for detecting and characterizing large DNA viruses and adenoviruses.
Larry A Hanson   +3 more
core   +1 more source

Emerging Ranaviral Infectious Diseases and Amphibian Decline

open access: yesDiversity, 2010
Infectious diseases caused by ranaviruses (RV, family Iridoviridae) not only affect wild amphibian populations but also agriculture and international animal trade.
Jacques Robert
doaj   +1 more source

The Role of Gut Microbiota in Fish Viral Infection: Mechanisms and Microbiota-Targeted Interventions. [PDF]

open access: yesAquac Nutr
Viral diseases represent one of the major threats to the global aquaculture industry. In recent years, the relationship between gut microbiota and viral infections in fish has garnered increasing attention. The gut microbiota contributes critically to fish health and is involved in antiviral defense through immune regulation, secretion of microbial ...
Zhao Q, Shao J, Chen Y, Zhang H.
europepmc   +2 more sources

Recombinant Ranaviruses for Studying Evolution of Host–Pathogen Interactions in Ectothermic Vertebrates

open access: yesViruses, 2016
Ranaviruses (Iridoviridae) are large DNA viruses that are causing emerging infectious diseases at an alarming rate in both wild and captive cold blood vertebrate species all over the world. Although the general biology of these viruses that presents some
Jacques Robert, James K. Jancovich
doaj   +1 more source

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