Virus-Targeted Transcriptomic Analyses Implicate Ranaviral Interaction with Host Interferon Response in Frog Virus 3-Infected Frog Tissues [PDF]
Viruses, 2021 Ranaviruses (Iridoviridae), including Frog Virus 3 (FV3), are large dsDNA viruses that cause devastating infections globally in amphibians, fish, and reptiles, and contribute to catastrophic amphibian declines.
Yun Tian +5 more
doaj +4 more sources
Class A Scavenger Receptors Are Used by Frog Virus 3 During Its Cellular Entry [PDF]
Viruses, 2019 Frog virus 3 (FV3) is the type species of the genus Ranavirus (family Iridoviridae). FV3 and FV3-like viruses are globally distributed infectious agents with the capacity to replicate in three vertebrate classes (teleosts, amphibians, and reptiles).
Nguyen T. K. Vo +4 more
doaj +4 more sources
The Roles of Amphibian (Xenopus laevis) Macrophages during Chronic Frog Virus 3 Infections [PDF]
Viruses, 2021 Infections by Frog Virus 3 (FV3) and other ranavirus genus members are significantly contributing to global amphibian decline. The Xenopus laevis frog is an ideal research platform upon which to study the roles of distinct frog leukocyte populations ...
Muhammad Riadul Haque Hossainey +4 more
doaj +2 more sources
Components of the Nucleotide Salvage Pathway Increase Frog Virus 3 (FV3) Replication [PDF]
Viruses, 2023 Viruses are obligate intracellular parasites that alter host metabolic machinery to obtain energy and macromolecules that are pivotal for replication.
Samantha R. Logan +3 more
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Amphibian (Xenopus laevis) Tadpoles and Adult Frogs Differ in Their Antiviral Responses to Intestinal Frog Virus 3 Infections [PDF]
Frontiers in Immunology, 2021 The global amphibian declines are compounded by ranavirus infections such as Frog Virus 3 (FV3), and amphibian tadpoles more frequently succumb to these pathogens than adult animals.
Kelsey A. Hauser +7 more
doaj +2 more sources
Targeted Transcriptomics of Frog Virus 3 in Infected Frog Tissues Reveal Non-Coding Regulatory Elements and microRNAs in the Ranaviral Genome and Their Potential Interaction with Host Immune Response [PDF]
Frontiers in Immunology, 2021 BackgroundFrog Virus 3 (FV3) is a large dsDNA virus belonging to Ranaviruses of family Iridoviridae. Ranaviruses infect cold-blood vertebrates including amphibians, fish and reptiles, and contribute to catastrophic amphibian declines. FV3 has a genome at
Yun Tian +5 more
doaj +2 more sources
Complete Genome Sequence of <i>Frog virus 3</i>, Isolated from a Strawberry Poison Frog (<i>Oophaga pumilio</i>) Imported from Nicaragua into the Netherlands. [PDF]
Genome Announc, 2017 Frog virus 3 was isolated from a strawberry poison frog (Oophaga pumilio) imported from Nicaragua via Germany to the Netherlands, and its complete genome sequence was determined.
Saucedo B +7 more
europepmc +7 more sources
Localization of Frog Virus 3 Conserved Viral Proteins 88R, 91R, and 94L [PDF]
Viruses, 2019 The characterization of the function of conserved viral genes is central to developing a greater understanding of important aspects of viral replication or pathogenesis.
Emily Penny, Craig R. Brunetti
doaj +2 more sources
Non-Lethal Detection of Frog Virus 3-Like (RUK13) and Common Midwife Toad Virus-Like (PDE18) Ranaviruses in Two UK-Native Amphibian Species [PDF]
Viruses, 2022 Ranaviruses have been involved in amphibian mass mortality events worldwide. Effective screening to control this pathogen is essential; however, current sampling methods are unsuitable for the detection of subclinical infections.
Charlotte E. Ford +7 more
doaj +2 more sources
Expression of frog virus 3 genes is impaired in mammalian cell lines [PDF]
Virology Journal, 2008 Frog virus 3 (FV3) is a large DNA virus that is the prototypic member of the family Iridoviridae. To examine levels of FV3 gene expression we generated a polyclonal antibody against the FV3 protein 75L.
Metcalf Julie +2 more
doaj +4 more sources