Antibody dependent enhancement of frog virus 3 infection [PDF]
Background Viruses included in the family Iridoviridae are large, icosahedral, dsDNA viruses that are subdivided into 5 genera. Frog virus 3 (FV3) is the type species of the genus Ranavirus and the best studied iridovirus at the molecular level ...
Penny Emily +2 more
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Phosphonoacetic Acid Inhibition of Frog Virus 3 Replication [PDF]
Phosphonoacetic acid at concentrations above 200 μg/ml inhibited the replication of frog virus 3 in BHK cells. The inhibition of viral DNA replication observed in these cells was reversible and correlated with the inhibition of the virus-induced DNA polymerase activity in an in vitro assay.
R M, Elliott, A, Bateson, D C, Kelly
core +7 more sources
Ranid Herpesvirus 3 Infection in Common Frog Rana temporaria Tadpoles [PDF]
Ranid herpesvirus 3 (RaHV3) is a recently discovered virus associated with skin disease in frogs. We detected RaHV3 DNA in free-ranging common frog (Rana temporaria) tadpoles, consistent with premetamorphic infection.
Francesco C. Origgi, Annette Taugbøl
doaj +2 more sources
Cytokinins Reduce Viral Replication and Alter Plaque Morphology of Frog Virus 3 In Vitro [PDF]
Cytokinins (CKs) are a group of N6-substituted signaling molecules whose biosynthesis and metabolism have been documented in all kingdoms of life, including vertebrates.
Mark Seegobin +3 more
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First Report of Endemic Frog Virus 3 (FV3)-like Ranaviruses in the Korean Clawed Salamander (Onychodactylus koreanus) in Asia [PDF]
Frog virus 3 (FV3) in the genus Ranavirus of the family Iridoviridae causes mass mortality in both anurans and urodeles worldwide; however, the phylogenetic origin of FV3-like ranaviruses is not well established.
Jongsun Kim +4 more
doaj +2 more sources
Detection of Frog Virus 3 by Integrating RPA-CRISPR/Cas12a-SPM with Deep Learning [PDF]
Zhengyang Lei +19 more
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Expression of frog virus 3 genes is impaired in mammalian cell lines [PDF]
Frog virus 3 (FV3) is a large DNA virus that is the prototypic member of the family Iridoviridae. To examine levels of FV3 gene expression we generated a polyclonal antibody against the FV3 protein 75L.
Metcalf Julie +2 more
doaj +4 more sources
Critical Role of an MHC Class I-Like/Innate-Like T Cell Immune Surveillance System in Host Defense against Ranavirus (Frog Virus 3) Infection [PDF]
Besides the central role of classical Major Histocompatibility Complex (MHC) class Ia-restricted conventional Cluster of Differentiation 8 (CD8) T cells in antiviral host immune response, the amphibian Xenopus laevis critically rely on MHC class I-like ...
Eva-Stina Isabella Edholm +4 more
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The Molecular Biology of Frog Virus 3 and other Iridoviruses Infecting Cold-Blooded Vertebrates [PDF]
Frog virus 3 (FV3) is the best characterized member of the family Iridoviridae. FV3 study has provided insights into the replication of other family members, and has served as a model of viral transcription, genome replication, and virus-mediated host ...
Kwang H. Yu +2 more
doaj +2 more sources
Case report: ranavirus infections in captive eastern box turtles (Terrapene carolina carolina) in Japan [PDF]
Ranaviruses are broad host-range pathogens that cause fatal infections in ectothermic vertebrates, including fish, amphibians, and reptiles and are considered emerging infectious diseases. This report describes a case of ranavirus infection identified at
Kenichi Tamukai +4 more
doaj +2 more sources

