Inflammation-induced reactivation of the ranavirus Frog Virus 3 in asymptomatic Xenopus laevis. [PDF]
Natural infections of ectothermic vertebrates by ranaviruses (RV, family Iridoviridae) are rapidly increasing, with an alarming expansion of RV tropism and resulting die-offs of numerous animal populations.
Jacques Robert +4 more
doaj +4 more sources
Isolation and Characterization of a Frog Virus 3 Strain from a Wood Frog (Rana sylvatica) in Wood Buffalo National Park [PDF]
Members of the Iridoviridae family, genus Ranavirus, represent a group of globally emerging pathogens of ecological and economic importance. In 2017, an amphibian die-off of wood frogs (Rana sylvatica) and boreal chorus frogs (Pseudacris maculata) was ...
Samantha R. Logan +5 more
doaj +4 more sources
The Molecular Biology of Frog Virus 3 and other Iridoviruses Infecting Cold-Blooded Vertebrates [PDF]
Frog virus 3 (FV3) is the best characterized member of the family Iridoviridae. FV3 study has provided insights into the replication of other family members, and has served as a model of viral transcription, genome replication, and virus-mediated host ...
Kwang H. Yu +2 more
doaj +4 more sources
Cytokinins Reduce Viral Replication and Alter Plaque Morphology of Frog Virus 3 In Vitro [PDF]
Cytokinins (CKs) are a group of N6-substituted signaling molecules whose biosynthesis and metabolism have been documented in all kingdoms of life, including vertebrates.
Mark Seegobin +3 more
doaj +4 more sources
Waterborne infectivity of the Ranavirus frog virus 3 in Xenopus laevis. [PDF]
Ranaviruses like frog virus 3 (FV3) are responsible for emerging infectious diseases spreading worldwide to fish, amphibian and reptilian species. We have developed, in Xenopus laevis, an experimental model to investigate viral transmission. We show that FV3 released in water by immunocompromised infected adults can infect adult and larval stages of ...
Robert J +3 more
europepmc +5 more sources
Frog Virus 3 Genomes Reveal Prevalent Recombination between Ranavirus Lineages and Their Origins in Canada [PDF]
Ranaviruses are pathogens associated with the decline of amphibian populations across much of their distribution. In North America, frog virus 3 (FV3) is a widely distributed pathogen with wild populations of amphibians harboring different lineages and ...
Craig Brunetti +2 more
exaly +4 more sources
Phosphonoacetic Acid Inhibition of Frog Virus 3 Replication [PDF]
Phosphonoacetic acid at concentrations above 200 μg/ml inhibited the replication of frog virus 3 in BHK cells. The inhibition of viral DNA replication observed in these cells was reversible and correlated with the inhibition of the virus-induced DNA polymerase activity in an in vitro assay.
R M, Elliott, A, Bateson, D C, Kelly
core +6 more sources
Expression of frog virus 3 genes is impaired in mammalian cell lines [PDF]
Frog virus 3 (FV3) is a large DNA virus that is the prototypic member of the family Iridoviridae. To examine levels of FV3 gene expression we generated a polyclonal antibody against the FV3 protein 75L.
Metcalf Julie +2 more
doaj +7 more sources
Ranid Herpesvirus 3 Infection in Common Frog Rana temporaria Tadpoles [PDF]
Ranid herpesvirus 3 (RaHV3) is a recently discovered virus associated with skin disease in frogs. We detected RaHV3 DNA in free-ranging common frog (Rana temporaria) tadpoles, consistent with premetamorphic infection.
Francesco C. Origgi, Annette Taugbøl
doaj +4 more sources
First Report of Endemic Frog Virus 3 (FV3)-like Ranaviruses in the Korean Clawed Salamander (Onychodactylus koreanus) in Asia [PDF]
Frog virus 3 (FV3) in the genus Ranavirus of the family Iridoviridae causes mass mortality in both anurans and urodeles worldwide; however, the phylogenetic origin of FV3-like ranaviruses is not well established.
Jongsun Kim +4 more
doaj +2 more sources

