Macromolecular synthesis in cells infected by frog virus 3. VI. Frog virus 3 replication is dependent on the cell nucleus [PDF]
Previous evidence indicated that frog virus 3 (FV3), an icosahedral DNA virus, replicates exclusively in the cytoplasm. However, data presented here demonstrate that FV3 does not replicate in UV-irradiated or enuleated chicken embryo or BSC-1 cells and that virus-specific DNA synthesis is not initiated in such cells.
R, Goorha, D B, Willis, A, Granoff
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Environmental DNA (eDNA) collection has emerged as a powerful and noninvasive wildlife population and pathogen‐monitoring tool. Ranavirus is an emerging pathogen linked to die‐offs in amphibian species.
Alyssa W. Kaganer +4 more
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Frog Virus 3 Deoxyribonucleic Acid
Summary DNA extracted from frog virus 3 has a GC mol fraction of about 0.56. The mol. wt. of the DNA is about 100 × 106 (97 × 106 by neutral sucrose gradient sedimentation; 102 × 106 from renaturation kinetics). Analysis by neutral sucrose sedimentation indicated that the DNA exists as a single heteroduplex in the virus particle.
D C, Kelly, R J, Avery
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Evidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus). [PDF]
(c) 2009 Teacher et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Trenton W J Garner +11 more
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Experimental evidence in support of single host maintenance of a multihost pathogen [PDF]
Copyright: 2014 Duffus et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Duffus, ALJ, Garner, TWJ, Nichols, RA
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Experimental Frog Virus 3 infection using Brazilian strain: amphibians susceptibility [PDF]
Um número alarmante de notificações globais sobre surtos de mortalidade de anfíbios tem sido realizado nos últimos anos. As doenças emergentes destacam-se como as principais causas potenciais.
Ferreira, Cláudia Maris +6 more
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Mechanistic models are critical for our understanding of both within-host dynamics (i.e., pathogen replication and immune system processes) and among-host dynamics (i.e., transmission). Within-host models, however, are not often fit to experimental data,
Joseph R. Mihaljevic +2 more
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The replication of frog virus 3 in an amphibian cell line (XTC-2) derived from Xenopus laevis [PDF]
Frog virus 3 (FV3) has been demonstrated to replicate in a Xenopus laevis cell line, XTC-2. The virus has been titrated in XTC-2 cells by plaque assay, but the efficiency of plaquing is lower than in minnow or hamster cells.
Arnold, M.K., Kelly, D.C., Elliott, R.M.
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Frog virus 3 replication: induction and intracellular distribution of polypeptides in infected cells [PDF]
The synthesis of the polypeptides induced in frog virus 3-infected cells was analyzed by high-resolution sodium dodecyl sulfate-polyacrylamide gel electrophoresis of radiolabeled cell extracts.
Kelly, D.C., Elliott, R.M.
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Response of the Italian agile frog (Rana latastei) to a Ranavirus, frog virus 3: a model for viral emergence in naïve populations. [PDF]
Ranavirus (family Iridoviridae) is a genus of pathogens of poikilotherms, and some ranaviruses may play a role in widespread mortality of amphibians. Ecology of viral transmission in amphibians is poorly known but can be addressed through experimentation
Garner, T W J +3 more
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