Results 31 to 40 of about 89,101,627 (169)
Frog Virus 3 Deoxyribonucleic Acid
Summary DNA extracted from frog virus 3 has a GC mol fraction of about 0.56. The mol. wt. of the DNA is about 100 × 106 (97 × 106 by neutral sucrose gradient sedimentation; 102 × 106 from renaturation kinetics). Analysis by neutral sucrose sedimentation indicated that the DNA exists as a single heteroduplex in the virus particle.
D C, Kelly, R J, Avery
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Waterborne infectivity of the Ranavirus frog virus 3 in Xenopus laevis. [PDF]
Ranaviruses like frog virus 3 (FV3) are responsible for emerging infectious diseases spreading worldwide to fish, amphibian and reptilian species. We have developed, in Xenopus laevis, an experimental model to investigate viral transmission. We show that FV3 released in water by immunocompromised infected adults can infect adult and larval stages of ...
Robert J +3 more
europepmc +3 more sources
Mechanistic models are critical for our understanding of both within-host dynamics (i.e., pathogen replication and immune system processes) and among-host dynamics (i.e., transmission). Within-host models, however, are not often fit to experimental data,
Joseph R. Mihaljevic +2 more
doaj +1 more source
Ranaviruses in captive and wild Australian lizards
Ranaviral infections have been associated with mass mortality events in captive and wild amphibian, fish, and reptile populations globally. In Australia, two distinct types of ranaviruses have been isolated: epizootic haematopoietic necrosis virus in ...
Alicia Maclaine +4 more
doaj +1 more source
Induction of apoptosis in frog virus 3-infected cells
The ability of frog virus 3 (FV3), the type species of the family Iridoviridae, to induce apoptosis was examined by monitoring DNA cleavage, chromatin condensation, and cell-surface expression of phosphotidylserine (PS) in fathead minnow (FHM) and baby hamster kidney (BHK) cells.
Chinchar, V.G +4 more
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Immune Evasion Strategies of Ranaviruses and Innate Immune Responses to These Emerging Pathogens
Ranaviruses (RV, <em>Iridoviridae</em>) are large double-stranded DNA viruses that infect fish, amphibians and reptiles. For ecological and commercial reasons, considerable attention has been drawn to the increasing prevalence of ranaviral ...
Leon Grayfer +4 more
doaj +1 more source
Discovery of granulocyte-lineage cells in the skin of the amphibian Xenopus laevis
The ranavirus Frog Virus 3 (FV3) and the chytrid fungus Batrachochytrium dendrobatidis (Bd) are significant contributors to the global amphibian declines and both pathogens target the amphibian skin.
Kelsey Hauser +8 more
doaj +1 more source
Degradation of Single- and Double-Stranded RNA by Frog Virus 3 [PDF]
Purified preparations of frog virus 3 possess ribonuclease activities directed against single-and double-stranded RNA. Double-stranded RNAs isolated from purified reovirus type 3 and from HeLa cells infected with poliovirus and single-stranded poliovirus RNA from purified virus are readily degraded by incubation with frog virus 3. The mode of action of
P, Palese, G, Koch
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