Results 101 to 110 of about 1,793,034 (245)

Investigating the Cytoskeleton of DRGs Using Cryo‐Electron Microscopy and Deep Learning

Cytoskeleton, EarlyView.
ABSTRACT We describe a method for determining the ultrastructural organization of axons and varicosities of cultured dorsal root ganglion (DRG) neurons using cryogenic electron microscopy (cryo‐EM). Cryo‐EM reveals the dimensions, proximity, and overall organization of biological specimens in a near‐native state, avoiding artifacts of fixation and ...
M. Neal Waxham, Mihir Relan, Matthew T. Swulius, Andrea K. H. Stavoe   +3 more
wiley   +1 more source

Embedding patient engagement in the R&D process of a life sciences company through co-creation with a patient expert R&D board: a case study

Research Involvement and Engagement
Patient involvement is crucial in healthcare, a factor increasingly recognised by life sciences companies and research institutes. This article presents a case study on Servier, a life sciences company that founded a patient expert board, ahead of ...
Estelle Jobson, Marta Garcia, Danika Sharek, Laura Risueño, Sylvain Arnould, Aude Lemoine-André, Jan Geissler, Ana Amariutei, Sabrina Grigolo, Begonya Nafria Escalera, Thomas Smith, Oriana Sousa, Linda Stone, Janet West   +13 more
doaj   +1 more source

Clinical Reach into the Cognitive Space (CRITiCS): outline conceptual framework for safe use of generative artificial intelligence in mental health decision-making

BJPsych Bulletin
Aims and method Advances in generative artificial intelligence, particularly through large language models, like GPT-4, have opened opportunities to develop cognitive agents to enhance clinical productivity, especially in complex secondary and tertiary
Andrew Hider, Lesa Wright, Jacob Needle
doaj   +1 more source

iris: v1.10.0

, 2016
<p><a href="http://scitools.org.uk/iris/docs/v1.10.0/index.html">http://scitools.org.uk/iris/docs/v1.10.0/index.html</a> <a href="http://scitools.org.uk/iris/docs/v1.10.0/whatsnew/1.10.html">http://scitools.org.uk/iris/docs/v1.10 ...
Stephan Hoyer, kwilliams-mo, Ed Campbell, Bill Little, Joseph Hogg, David Murray, Phil Elson, Elliott Sales de Andrade, Corinne Bosley, Niall Robinson, Daniel Kirkham, marqh, Emma Hogan, Peter Killick, lbdreyer, Ruth Comer, Patrick Peglar, Armin Leuprecht, scmc72, Andrew Dawson, Richard Hattersley, Ian Edwards, Carwyn Pelley, munslowa, Byron Blay, Filipe, Andreas Hilboll, Jon Seddon, Phil Bentley, Jamie Kettleborough   +29 more
core   +1 more source

iris: v1.10.0rc1

, 2016
<p>see <a href="https://github.com/SciTools/iris/blob/17210500bedd0b36ef0b61bfc79e2a70cec398d1/docs/iris/src/whatsnew/1.10.rst">https://github.com/SciTools/iris/blob/17210500bedd0b36ef0b61bfc79e2a70cec398d1/docs/iris/src/whatsnew/1.10.rst</
Stephan Hoyer, kwilliams-mo, Ed Campbell, Bill Little, Joseph Hogg, David Murray, Phil Elson, Elliott Sales de Andrade, Corinne Bosley, Niall Robinson, Daniel Kirkham, marqh, Emma Hogan, Peter Killick, lbdreyer, Ruth Comer, Patrick Peglar, Armin Leuprecht, scmc72, Andrew Dawson, Richard Hattersley, Ian Edwards, Carwyn Pelley, munslowa, Byron Blay, Filipe, Andreas Hilboll, Jon Seddon, Phil Bentley, Jamie Kettleborough   +29 more
core   +1 more source

The Effect of Electrolyte pH and Impurities on the Stability of Electrolytic Bicarbonate Conversion

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
The performance of bicarbonate electrolysis is largely controlled by the electrolyte inlet pH, the distance between the membrane and electrode, and the impurities present in the electrolyte. By complexing trace metal ions with ethylenediaminetetraacetic acid (EDTA), stability can significantly be improved and longer term operation can be achieved ...
Iris Burgers, Jón Jónasson, Earl Goetheer, Ruud Kortlever   +3 more
wiley   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

MIT/TFE family transcription factors, Mitf and Tfec, redundantly promote pigment cell differentiation and retinal epithelium pigmentation in teleosts

Developmental Dynamics, EarlyView.
Abstract Background Transcription factors of the MIT/TFE family—mitfa, mitfb, and tfec—play essential roles in specifying pigment cells derived from neural crest cells in vertebrates. In teleosts, which possess multiple pigment cell types, these factors exhibit partially redundant but largely distinct functions across different pigment lineages.
James Lister, Keisuke Sugiwaka, Tetsuaki Kimura, Rieko Tanaka, Makoto Goda, Hikaru Kobayashi, Chikako Inoue, Kawilarang W. A. Masengi, Kazunori Yamahira, Kiyoshi Naruse, Satoshi Ansai, Robert N. Kelsh, Masahiko Hibi, Hisashi Hashimoto   +13 more
wiley   +1 more source

Low‐Dimensional Materials and Van Der Waals Heterostructures for Energy Application: A Comprehensive Review

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Low‐dimensional materials (0D, 1D, and 2D) exhibit unique electronic and physicochemical properties, enabling advanced nanoelectronic and optoelectronic devices. Mixed‐dimensional heterostructures combine these materials to enhance functionality.
Qaisar Alam, Sajjad Ali, Pir Muhammad Ismail, ABM Sharif Hossain   +3 more
wiley   +1 more source

A novel convolutional feature-based method for predicting limited mobility eye gaze direction

IJAIN (International Journal of Advances in Intelligent Informatics)
Eye gaze direction is a critical issue since several applications in computer vision technology rely on determining gaze direction, where individuals move their eyes to limited mobility locations for sensory information.
Amal Hameed Khaleel, Thekra H Abbas, Abdul-Wahab Sami Ibrahim   +2 more
doaj   +1 more source