Results 31 to 40 of about 2,206,905 (180)
Defect‐Templated Phase Engineering in Atomically Thin Metals
Advanced Materials, EarlyView.Graphene defects are transformed from passive imperfections into programmable templates for phase‐selective growth of atomically thin silver. Plasma‐generated boundary defects favor Ag(1), whereas sp3‐rich zero‐layer graphene promotes Ag(2). This defect‐directed intercalation links local graphene chemistry to crystalline phase, electronic structure ...Arpit Jain, Boyang Zheng, Sawani Datta, Kanchan Ulman, Jakob Henz, Matthew Wei‐Jun Liu, Van Dong Pham, Wen He, Chengye Dong, Li‐Syuan Lu, Alexander Vera, Nader Sawtarie, Wesley Auker, Ke Wang, Bob Hengstebeck, Zachary W. Henshaw, Shreya Mathela, Maxwell Wetherington, William H. Blades, Kenneth Knappenberger, Ursula Wurstbauer, Su Ying Quek, Ulrich Starke, Shengxi Huang, Vincent H. Crespi, Joshua A. Robinson +25 morewiley +1 more sourceSystematic Prioritization of Candidate Genes in Disease Loci Identifies TRAFD1 as a Master Regulator of IFNγ Signaling in Celiac Disease
Frontiers in Genetics, 2021 Celiac disease (CeD) is a complex T cell-mediated enteropathy induced by gluten. Although genome-wide association studies have identified numerous genomic regions associated with CeD, it is difficult to accurately pinpoint which genes in these loci are ...Adriaan van der Graaf, Maria M. Zorro, Annique Claringbould, Urmo Võsa, Urmo Võsa, Raúl Aguirre-Gamboa, Chan Li, Chan Li, Joram Mooiweer, Isis Ricaño-Ponce, Zuzanna Borek, Zuzanna Borek, Frits Koning, Yvonne Kooy-Winkelaar, Ludvig M. Sollid, Shuo-Wang Qiao, Vinod Kumar, Vinod Kumar, Yang Li, Yang Li, Yang Li, Lude Franke, Sebo Withoff, Cisca Wijmenga, Cisca Wijmenga, Serena Sanna, Serena Sanna, Iris Jonkers, Iris Jonkers, BIOS Consortium +29 moredoaj +1 more sourceSpatially Informed Feature Selection and Machine Learning in Matrix‐Assisted Laser Desorption/Ionization Imaging for Cohort‐Scale Molecular Tissue Phenomics in Glioblastoma
Advanced Intelligent Discovery, EarlyView.Matrix‐assisted laser desorption/ionization imaging‐based identification of reliable small molecule markers across heterogeneous glioblastoma cohorts is challenging with intensity‐only methods. We present spatially informed feature selection (SIFS), a spatially informed framework that prioritizes molecules consistently colocalizing with histopathology. Shad A. Mohammed, Denis Abu Sammour, Dirk C. Hoffmann, Philipp Sievers, Tobias Bausbacher, Melissa Hahn, Yasemin Ucal, Iris Mildenberger, Christiane A. Opitz, Stefan Schmidt, Michael Platten, Oliver Wasenmüller, Wolfgang Wick, Andreas von Deimling, Tobias Kessler, Carsten Hopf +15 morewiley +1 more sourceGenetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits
Genome Medicine, 2017 Background Age-related macular degeneration (AMD) is a common condition of vision loss with disease development strongly influenced by environmental and genetic factors. Recently, 34 loci were associated with AMD at genome-wide significance.Felix Grassmann, Christina Kiel, Martina E. Zimmermann, Mathias Gorski, Veronika Grassmann, Klaus Stark, International AMD Genomics Consortium (IAMDGC), Iris M. Heid, Bernhard H. F. Weber +8 moredoaj +1 more sourceImplementation and use of risk minimization control tools in the EU: A multistakeholder survey
British Journal of Clinical Pharmacology, EarlyView.Aims
This study characterized stakeholders' experiences with national implementation of risk minimization control tools (RMCTs), such as healthcare professional qualification, healthcare facility accreditation and medical intervention prior to treatment initiation, for eight medicinal products across eight European Union countries. Methods
We conducted Sharon C. M. Essink, Iris R. Joosse, Maximilian Salcher‐Konrad, Melanie Walter, Elena Deligianni, Dimitra Tsioumela, Christos Kontogiorgis, Elita Poplavska, Iluta Žīgure, Christina E. Hoeve, Teresa Leonardo Alves, Ella D. van Vliet, Renato Ferreira‐da‐Silva, Ana Kodrič, Mitja Kos, Juan Erviti, Marta Gutiérrez‐Valencia, Luis Carlos Saiz, Sofia Kälvemark Sporrong, Emelie Karlsson, Christine Leopold, Marie L. De Bruin +21 morewiley +1 more sourceSex Differences in Fall Frequency, Risk Factors, and Outcomes in Parkinson's Disease: A Cross‐Sectional Analysis
Movement Disorders Clinical Practice, EarlyView.Abstract Background
Female sex is an independent fall risk factor in Parkinson's disease (PD), yet sex‐specific fall patterns remain unclear. Objectives
To compare sex‐specific fall risk and outcomes across PD, prodromal alpha‐synucleinopathy (PAS), and healthy controls (HC); estimate fall frequency across PD progression; and assess how sex modifies ...Joaquin A. Vizcarra, Kat Hefter, David‐Erick Lafontant, Michael Tran Duong, Ashkan Ertefaie, Brian Litt, Dani S. Bassett, Andrew Siderowf, The Parkinson's Progression Markers Initiative, Kenneth Marek, Caroline Tanner, Tanya Simuni, Andrew Siderowf, Douglas Galasko, Lana Chahine, Christopher Coffey, Kalpana Merchant, Kathleen Poston, Roseanne Dobkin, Tatiana Foroud, Brit Mollenhauer, Dan Weintraub, Ethan Brown, Karl Kieburtz, Mark Frasier, Todd Sherer, Sohini Chowdhury, Roy Alcalay, Aleksandar Videnovic, Duygu Tosun‐Turgut, Werner Poewe, Susan Bressman, Jan Hammer, Raymond James, Ekemini Riley, John Seibyl, Leslie Shaw, David Standaert, Sneha Mantri, Nabila Dahodwala, Michael Schwarzschild, Connie Marras, Hubert Fernandez, Ira Shoulson, Helen Rowbotham, Paola Casalin, Claudia Trenkwalder, Todd Sherer, Sohini Chowdhury, Mark Frasier, Jamie Eberling, Katie Kopil, Alyssa O’Grady, Maggie McGuire Kuhl, Leslie Kirsch, Tawny Willson, Emily Flagg, Tanya Simuni, Bridget McMahon, Craig Stanley, Kim Fabrizio, Dixie Ecklund, Trevis Huff, Tatiana Foroud, Laura Heathers, Christopher Hobbick, Gena Antonopoulos, John Seibyl, Kathleen Poston, Christopher Coffey, Chelsea Caspell‐Garcia, Michael Brumm, Bioinformatics Core, Arthur Toga, Karen Crawford, Tatiana Foroud, Jan Hamer, Brit Mollenhauer, Doug Galasko, Kalpana Merchant, Andrew Singleton, Tatiana Foroud, Thomas Montine, Caroline Tanner, Carlie Tanner, Ethan Brown, Lana Chahine, Roseann Dobkin, Monica Korell, Charles Adler, Roy Alcalay, Amy Amara, Paolo Barone, Bastiaan Bloem, Kathrin Brockmann, Norbert Brüggemann, Lana Chahine, Kelvin Chou, Nabila Dahodwala, Alberto Espay, Stewart Factor, Hubert Fernandez, Michelle Fullard, Douglas Galasko, Penelope Hogarth, Shu‐Ching Hu, Michele Hu, Stuart Isaacson, Christine Klein, Rejko Krueger, Mark Lew, Zoltan Mari, Connie Marras, Maria Jose Martí, Nikolaus McFarland, Tiago Mestre, Brit Mollenhauer, Emile Moukheiber, Alastair Noyce, Wolfgang Oertel, Njideka Okubadejo, Sarah O’Shea, Rajesh Pahwa, Nicola Pavese, Werner Poewe, Ron Postuma, Giulietta Riboldi, Lauren Ruffrage, Javier Ruiz Martinez, David Russell, Marie H. Saint‐Hilaire, Neil Santos, Wesley Schlett, Ruth Schneider, Holly Shill, David Shprecher, Tanya Simuni, David Standaert, Leonidas Stefanis, Yen Tai, Caroline Tanner, Arjun Tarakad, Eduardo Tolosa, Aleksandar Videnovic, Susan Ainscough, Courtney Blair, Erica Botting, Isabella Chung, Kelly Clark, Ioana Croitoru, Kelly DeLano, Iris Egner, Fahrial Esha, May Eshel, Frank Ferrari, Victoria Kate Foster, Alicia Garrido, Madita. Grümmer, Bethzaida Herrera, Ella Hilt, Chloe Huntzinger, Raymond James, Farah Kausar, Christos Koros, Yara Krasowski, Dustin Le, Ying Liu, Taina M. Marques, Helen Mejia Santana, Sherri Mosovsky, Jennifer Mule, Philip Ng, Lauren O’Brien, Abiola Ogunleye, Oluwadamilola Ojo, Obi Onyinanya, Lisbeth Pennente, Romina Perrotti, Michael Pileggi, Ashwini Ramachandran, Deborah Raymond, Jamil Razzaque, Shawna Reddie, Kori Ribb, Kyle Rizer, Janelle Rodriguez, Stephanie Roman, Clarissa Sanchez, Cristina Simonet, Anisha Singh, Elisabeth Sittig, Angela Stovall, Bobbie Stubbeman, Alejandra Valenzuela, Catherine Wandell, Diana Willeke, Karen Williams, Dilinuer Wubuli +197 morewiley +1 more sourceSoil health assessment using buried cotton underpants with the help of 1000 citizen scientists
PLANTS, PEOPLE, PLANET, EarlyView.Soil is a vital resource for life on Earth. Although many soils are degraded, societal awareness of soil‐related issues is limited. To highlight soil as a key resource and fascinating study system, we initiated a citizen science project together with 1000 participants investigating soil health across Switzerland using buried cotton underpants.S. Franz Bender, Diane Bürge, Luca Bragazza, Eva Knop, Sandie Masson, Noemi Peter, Romina Demarmels, Daniel Mueller, Ariane Imhof, Pia Viviani, Atlant Bieri, Frank Liebisch, Stefan Geisen, Yann Hautier, Panos Panagos, Pablo Garcia‐Palacios, Marta Goberna, David Johnson, Simon Jöhr, Alain Valzano‐Held, Claudia Weik, Nadine Gloor, Heidi Aguilar, Marco Agustoni, Barbara Albertoni, Regina Anderson, Alberto Andreani, Bénédicte Arguillère, Osvaldo Arrigo, Barbara Auer, Vanessa Badà, Brigitte Baenteli, Gaëlle Balleys, Dagmar Bay, Daniel Beck, Martina Becker, Alma Bender‐Freisinger, Sarah Benoit, Barbara Bernasconi, Chiara Bernasconi, Marco Bertschinger, Michael Bessard, David Bichsel, David Bichsel, Matteo Binda, Joel Bischof, Ruth Bischof, Bernadette Bisig, Andreas Bitterli, Natacha Bodenhausen, Yann Bonjour, Lucien Bovy, Tanja Boyandin, Eliane Breitenmoser, Christian Brönimann, Nathalie Brückner, Marcel Bucher, Stefan Bucher, Andreas Cadonau, Simone Cairoli, Elodie Calais, Bruno Campana, Catrina Canetta Collenberg, Davide Carrara, Cristian Cattaneo, Ester‐Camilla Cattaneo, Renzo Cattori, Silvana Cavagna, Luciano‐Grazia Cavallini, Elio Cavargna, Laura Cerri, Marlis Chanton, Camilla Chiesa, Elisabeth Clément, Morgane Clivaz‐Duc, Léonie Cocquio, Helio Correia, Cristina Corti, Stefano Corti, Fabien Dauphin, Annette Délétroz, Nicola Della Casa, Francesco Denova, Yannick Ducommun, Jacques Dugon, Monique Duplan, Lisa Ehrler, Bruno Enz, Philipp Fässler, Alain Favre, Urs Fellmann, Nadine Fischer, Serge Fischer, Johann‐Peter Flisch, Franklyn Foresti, Paola Frapolli, Simon Freiburghaus, Edie Freisinger, Peter Gamper, Agnes‐Julia Geissberger, Frères Girardin, Stephan Goppel, Fabiana Greco, Ueli Grossniklaus, Gabriela Grubenmann, Marc‐Henri Guex, Urs Hähni, Martina Haller, Gerhard Hardegger, Kyle Hartman, Anastase Hategekimana, Regula Hegglin, Matteus Heiter, Andreas Hellwig, Sandra‐John Hemsley, Chantal Herzog, Stephan Herzog, Ruedi Hess, Werner Hilber, Sarah‐Lea Hipp, Jolanda Hofmann, Mirjam Hofmann, Thomas Holdener, Mischa Hug, Erol Incesu, Sebastian Ineichen, David Iten, Regula‐Christoph Jakob, Peter Jann, Salomé‐David Jantz Bröckelmann, Markus Jocher, Simon Jöhr, Jasmin Joshi, Andreas Jud, Corinne Jud, Beatrice Jung, Daniel Jutzi, Walter Käch, Franziska‐Oli Kägi, Franziska Kaguembega‐Müller, Antonia Kaiser, Lukas Kammermann, Andreas Katz, Pirmin Kneubühler, Janique Koller, Eva Kollmann, Michèle Kraiem, Markus Künzler, Laura Kuonen, David Küttel, Romeo Ladina, Gabriella Lakatos, Anna Lazzarotto, Jean Lebedeff, Manuela Leonardi, Paola Leonardi, Simone Leoni, Eric Leuenberger, Corinne Lüthi, Sari Manaa, Simonetta Mauri, Harald Menzi, Vincenzo‐Corinne Meroni Held, Stephan Meyer, Stéphan Meylan, Matteo Minotti, Paola Molinari, Fabiola Monigatti, Vinciane Monod, Andrea Moroni‐Stampa, Jürg Moser, Res Moser, Alain Müller, Balz Müller, Laurence Müller, Nathalie Nevo, Stefan Odermatt, Lucia Oertle, Sandra Ott, Sébastien Oulevey, Ania Hans‐Peter Padrutt, Manuela Paltenghi, Nadia Paltenghi, Anna Parathazham, Nicolas Pavillard, Cesare Sonia Pedrazzini Giussani, Barbara Loris Pedroia, Alicia Perego, Paola Paolo Pieracci Cestari, Luisa Poggi, Mirko Ponti, Laurence Pot, Pierre‐Antoine Preti, Brice Prudat, Lina Rasheed, Dominique Raphael Reichenbach, Etienne Reichenbach, Beat Reidy, Ruedi Riniker, Chantal Ritter Cochand, Katharina Ritter, Julien Rondez, Fabien Roth, Adrian Rubi, Nicolas Ruch, Nicla‐Alex‐Mia‐Zoe‐Febe Rusca, Mirjam Rust, Erminia Salvi Knobloch, Alberto Sassella, Anke Schäfer, Beat Schär, Sabine Schärer, Patric Schatzmann, Belinda Schegg, Joël Scheidegger, Klaus Schläppi, Judith Schlegel, Marisa Schnüriger, Toni Schönbächler, Jürg Schönholzer, Coni Schweizer, Eugenio Scozzafava, Caroline Serafini, Tina Siegenthaler, Claudio Signer, Dustin Singer, Iris Solothurnmann, Rolf Sonderegger, Stefanie R. Spycher, Mirjam Stähli, Jean‐Pierre Stefanelli, Katja Stucki, Valentina Tanzi, Christina Thalmann, Sylvia Tiercy, Valentina Togni, Mathias Tönz, Paul Trachsel, Dino Troncatti, Pirmin‐Fredy Umbricht, Claude Valloton, Alexander van der Heijden, Liev van Moorsel, Sofia van Moorsel, Thea van Woerkom, Claude Varin, Manuela Villa‐Petraglio, Christophe Viltard, Florian Vogelsanger, Adrian von Niederhäusern, Barbara Walther, Jocelyn Widmer, Gianna Wullschleger, Thomas Würms, Thomas Wüthrich, Anita Zulliger, Renatus C. Zürcher, Thomas D. Bucheli, Marcel G. A. van der Heijden +258 morewiley +1 more sourceLifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study. [PDF]
PLoS ONE, 2008 Rare mutations of the low-density lipoprotein receptor gene (LDLR) cause familial hypercholesterolemia, which increases the risk for coronary artery disease (CAD).Patrick Linsel-Nitschke, Anika Götz, Jeanette Erdmann, Ingrid Braenne, Peter Braund, Christian Hengstenberg, Klaus Stark, Marcus Fischer, Stefan Schreiber, Nour Eddine El Mokhtari, Arne Schaefer, Jürgen Schrezenmeir, Diana Rubin, Anke Hinney, Thomas Reinehr, Christian Roth, Jan Ortlepp, Peter Hanrath, Alistair S Hall, Massimo Mangino, Wolfgang Lieb, Claudia Lamina, Iris M Heid, Angela Doering, Christian Gieger, Annette Peters, Thomas Meitinger, H-Erich Wichmann, Inke R König, Andreas Ziegler, Florian Kronenberg, Nilesh J Samani, Heribert Schunkert, Wellcome Trust Case Control Consortium (WTCCC), Cardiogenics Consortium +34 moredoaj +1 more source
