Results 61 to 70 of about 5,901 (142)
Psychiatrists effect on positive symptom severity and daily functioning during pharmacotherapy for first-episode psychosis patients
Scientific ReportsClinical outcomes after a first-episode of psychosis (FEP) are heterogeneous. Many patient-related factors such as gender and comorbidity have been studied to predict symptomatic outcomes.Franciska de Beer, Sanne Koops, Robert A. Schoevers, Wim Veling, Nico van Beveren, Lieuwe de Haan, Nynke Boonstra, Martijn Kikkert, Marieke J. H. Begemann, HAMLETT-OPHELIA Consortium, Joran Lokkerbol, Iris E. C. Sommer +11 moredoaj +1 more sourceMAIT cells are activated during human viral infections
Nature Communications, 2016 Mucosal Associated Invariant T cells have been implicated in response to bacterial pathogens. Here the authors show that in human viral infections, these cells are activated by IL-18 in cooperation with other pro-inflammatory cytokines, producing ...Bonnie van Wilgenburg, Iris Scherwitzl, Edward C. Hutchinson, Tianqi Leng, Ayako Kurioka, Corinna Kulicke, Catherine de Lara, Suzanne Cole, Sirijitt Vasanawathana, Wannee Limpitikul, Prida Malasit, Duncan Young, Laura Denney, STOP-HCV consortium, Michael D. Moore, Paolo Fabris, Maria Teresa Giordani, Ye Htun Oo, Stephen M. Laidlaw, Lynn B. Dustin, Ling-Pei Ho, Fiona M. Thompson, Narayan Ramamurthy, Juthathip Mongkolsapaya, Christian B. Willberg, Gavin R. Screaton, Paul Klenerman +26 moredoaj +1 more sourceReproducibility of cognitive endpoints in clinical trials: lessons from neurofibromatosis type 1
Annals of Clinical and Translational Neurology, 2019 Objective Rapid developments in understanding the molecular mechanisms underlying cognitive deficits in neurodevelopmental disorders have increased expectations for targeted, mechanism‐based treatments.Jonathan M. Payne, Stephen J. C. Hearps, Karin S. Walsh, Iris Paltin, Belinda Barton, Nicole J. Ullrich, Kristina M. Haebich, David Coghill, Gerard A. Gioia, Alan Cantor, Gary Cutter, James H. Tonsgard, David Viskochil, Celiane Rey‐Casserly, Elizabeth K. Schorry, Joseph D. Ackerson, Laura Klesse, Michael J. Fisher, David H. Gutmann, Tena Rosser, Roger J. Packer, Bruce Korf, Maria T. Acosta, Kathryn N. North, the NF Clinical Trials Consortium +24 moredoaj +1 more sourcePathogen-specific epidemiology and clinical trajectories of fungal infections after kidney transplantation: a prospective multicenter cohort study
BMC Infectious DiseasesBackground Fungal infections contribute substantially to morbidity and mortality after kidney transplantation, yet pathogen-specific epidemiology and clinical risk profiles remain incompletely defined.Iris Schröter, Daniela Schindler, Christian Morath, Lutz Renders, Joachim Andrassy, Nele Kanzelmeyer, Anja Schork, Martin Zeier, Thomas Giese, Claudia Sommerer, for the Transplant Cohort of the German Center for Infection Research (DZIF Transplant Cohort) Consortium +10 moredoaj +1 more sourceRenal transplantation in older recipients – results of the DZIF transplant cohort
BMC GeriatricsBackground Kidney transplantation in older adults is expanding, but detailed data on infection burden, antibiotic resistance, and sex-specific outcomes remain limited.Claudia Sommerer, Iris Schröter, Daniela Schindler, Anja Schork, Lutz Renders, Stephan Kemmner, Jonas Michael Willerding, Burkhard Tönshoff, Martin Zeier, Thomas Giese, the Transplant Cohort of the German Center for Infection Research (DZIF Transplant Cohort) Consortium +10 moredoaj +1 more sourceTransplant centers’ prophylaxis and monitoring strategies: a key determinant of current herpes and polyomavirus incidences – results from the DZIF kidney transplant cohort
BMC NephrologyBackground Herpes- and polyomaviruses are major opportunistic pathogens after renal transplantation. Despite established guidelines, there is limited data on transplant centers’ prophylaxis and monitoring strategies and centers’ adherence to these ...Claudia Sommerer, Iris Schröter, Katrin Gruneberg, Daniela Schindler, Christian Morath, Lutz Renders, Gunilla Einecke, Martina Guthoff, Uwe Heemann, Paul Schnitzler, Martin Zeier, Thomas Giese, the Transplant Cohort of the German Center for Infection Research (DZIF Transplant Cohort) Consortium +12 moredoaj +1 more sourceTransformers for rapid detection of airway stenosis and stridor
Scientific ReportsUpper airway stenosis is a potentially life-threatening condition involving the narrowing of the airway. In more severe cases, airway stenosis may be accompanied by stridor, a type of disordered breathing caused by turbulent airflow. Patients with airway James Anibal, Rebecca Doctor, Micah Boyer, Karlee Newberry, Iris De Santiago, Shaheen Awan, Yassmeen Abdel-Aty, Gregory Dion, Veronica Daoud, Hannah Huth, Stephanie Watts, Bradford J. Wood, David Clifton, Alexander Gelbard, Maria Powell, Jamie Toghranegar, the Bridge2AI Voice Consortium, Yael Bensoussan +17 moredoaj +1 more sourcePsychosocial factors associated with quality of life in cancer patients undergoing treatment: an umbrella review
Health and Quality of Life OutcomesBackground Cancer treatment greatly impacts physical and psychological functioning of cancer patients, negatively affecting their quality of life (QoL).Chiara Marzorati, Viktorya Voskanyan, Diana Sala, Roberto Grasso, Federico Borgogni, Ricardo Pietrobon, Iris van der Heide, Merel Engelaar, Nanne Bos, Augusto Caraceni, Norbert Couspel, Montse Ferrer, Mogens Groenvold, Stein Kaasa, Claudio Lombardo, Aude Sirven, Hugo Vachon, Alexandra Gilbert, Cinzia Brunelli, Giovanni Apolone, Gabriella Pravettoni, EUonQoL Consortium +21 moredoaj +1 more source