Results 41 to 50 of about 9,153,676 (288)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME IN HIV INFECTION

Инфекция и иммунитет, 2018
Antiretroviral therapy (ART) leads to suppression of HIV replication, contributes to increase in the number of CD4-lymphocytes count and  partial restoration or activation of the immune system.
E. V. Boeva, N. A. Belyakov
doaj   +1 more source

A case of syphilis associated with immune reconstitution inflammatory syndrome and review of the literature

AIDS Research and Therapy, 2023
Background Immune reconstitution inflammatory syndrome (IRIS) associated with syphilis has rarely been described in HIV-infected patients. Diagnosis can be challenging because it is not always possible to discern it from a recent infection or a worsening
Luca Pipitò, Alice Annalisa Medaglia, Marcello Trizzino, Silvia Bonura, Claudia Gioè, Paola Di Carlo, Claudia Colomba, Antonio Cascio   +7 more
doaj   +1 more source

Three-dimensional Hessian matrix-based quantitative vascular imaging of rat iris with optical-resolution photoacoustic microscopy in vivo

Journal of Biomedical Optics, 2018
. For the diagnosis and evaluation of ophthalmic diseases, imaging and quantitative characterization of vasculature in the iris are very important. The recently developed photoacoustic imaging, which is ultrasensitive in imaging endogenous hemoglobin ...
Huangxuan Zhao, Guangsong Wang, Riqiang Lin, Xiaojing Gong, Liang Song, Tan Li, Wenjia Wang, Kunya Zhang, Xiuqing Qian, Haixia Zhang, Lin Li, Zhicheng Liu, Chengbo Liu   +12 more
semanticscholar   +1 more source

A Gym for Cells—Direct Laser Writing of Magnetic Multilayered Micro Actuators for Mechanical Stimulation of Cells

Advanced Functional Materials, EarlyView.
Surface‐attached multilayer micromagnet systems are fabricated by two‐photon crosslinking. The pillar‐shaped micro actuators consist of a soft and flexible surface‐attached cell‐repellent hydrogel layer at the bottom, acting as a hinge and a cell‐adhesive hydrophobic polymer filled with magnetic nanoparticles.
Nicolas Geid, Ayman Husari, Eleonora Galli, Lukas Leffler, Pascal Tomakidi, Jürgen Rühe   +5 more
wiley   +1 more source

To Induce IRIS or Suppress It: The spectrum of Mycobacterium genavense in the antiretroviral era.

Clinical Infectious Diseases, 2020
Mycobacterium genavense is a challenging opportunistic pathogen to diagnose and manage in HIV patients. Persistent immune suppression or protracted immune reconstitution inflammatory syndrome can lead to complicated clinical courses.
M. Manion, N. Lynn, Luxin Pei, D. Hammoud, Elizabeth Laidlaw, G. Roby, Dorinda Metzger, Yolanda Mejia, A. Lisco, A. Zelazny, S. Holland, M. Vachon, Matthew L. Scherer, C. Bergin, I. Sereti   +14 more
semanticscholar   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source

Magnetic‐Guided Delivery of Antisense Oligonucleotides for Targeted Transduction in Multiple Retinal Explant and Organoid Models

Advanced Science, EarlyView.
Magnetic field‐guided MNP@ATR‐ASO nanocomplexes facilitate the targeted delivery of ASOs to ganglion cells or photoreceptors within retinal explants, thereby enhancing the efficacy of ASOs in correcting pre‐mRNA splicing abnormalities. Furthermore, the nanocomplexes improve ASO penetration and delivery in human retinal and inner ear organoid models ...
Xiuhong Ye, Sihui Chen, Wei Xiong, Fan Wang, Hon Fai Chan, Haocheng Lai, Xiangyu Guo, Tingting Yang, Shuhao Shen, Hang Chen, Wenxuan Wang, Guei‐Sheung Liu, Yonglong Guo, Jiansu Chen   +13 more
wiley   +1 more source

Síndrome Axenfeld-Rieger: Presentación de un caso Axenfeld-Rieger syndrome: A case report

Revista Cubana de Oftalmología, 2000
Se presenta el estudio clínico de un caso representativo del Síndrome de Axenfeld-Rieger. En el examen clínico se constató corectopia, policoria, hipoplasia iridiana, glaucoma, hipertelorismo, aplanamiento de la base de la nariz, hipoplasia maxilar ...
Daysi Flores Pérez, Yunia H. Labrada Rodríguez, Migdalis González Leyva   +2 more
doaj  

Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma

BMC Biology, 2006
Background DBA/2J (D2) mice develop an age-related form of glaucoma. Their eyes progressively develop iris pigment dispersion and iris atrophy followed by increased intraocular pressure (IOP) and glaucomatous optic nerve damage.
Cosma Ioan M, Mao Mao, Libby Richard T, Anderson Michael G, Wilson Larry A, Smith Richard S, John Simon WM   +6 more
doaj   +1 more source