Results 51 to 60 of about 9,153,676 (288)

Expanding the SIAH1‐Associated Phenotypic Spectrum: Insights From Loss‐of‐Function Variants

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT SIAH1 encodes for a RING‐type E3 ubiquitin ligase involved in protein ubiquitination. More specifically, it positively regulates Wnt signaling through promoting the accumulation of β‐catenin and mediates ubiquitination and degradation of Akt3 in neural development.
Liza Douiev   +14 more
wiley   +1 more source

Phytochemical Composition and In Vitro Biological Activity of Iris spp. (Iridaceae): A New Source of Bioactive Constituents for the Inhibition of Oral Bacterial Biofilms

open access: yesAntibiotics, 2020
The inhibition and eradication of oral biofilms is increasingly focused on the use of plant extracts as mouthwashes and toothpastes adjuvants. Here, we report on the chemical composition and the antibiofilm activity of 15 methanolic extracts of Iris ...
Lan Hoang   +11 more
doaj   +1 more source

What does it mean? Translating anatomical language to engage public audiences

open access: yesAnatomical Sciences Education, EarlyView.
Abstract The language of anatomy, with its roots in Ancient Greek and Roman languages, is complex and unfamiliar to many. Its complexity creates a significant barrier to public knowledge and understanding of anatomy—many members of the public find themselves asking “what does it mean?”, and this can manifest as poor health literacy and outcomes.
Kat A. Sanders, Adam M. Taylor
wiley   +1 more source

Study on the phytosanitary condition of introduced species of genus Iris L. in Donetsk Botanical Gardens of the NAS of Ukraine

open access: yesІнтродукція Рослин, 2010
The data on basic pests and diseases of irises in collection of Donetsk Botanical Gardens of the NAS of Ukraine are given. The basic struck culture was Iris hybrida hort., the basic pest was iris root-maggot fly, the basic disease was heterosporiosis ...
I.V. Bondarenko-Borisova   +2 more
doaj   +1 more source

The art and craft of anatomy

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Understanding human anatomy is crucial for improving public health outcomes; however, effective methods of engaging the public in this domain remain underexplored. This report investigates four hands‐on, creative, and accessible methods for enhancing anatomical knowledge during public engagement events: drawing, clay modeling, needle felting ...
Janet Philp, Joan Smith
wiley   +1 more source

A Paradoxical Treatment for a Paradoxical Condition: Infliximab Use in Three Cases of Mycobacterial IRIS.

open access: yesClinical Infectious Diseases, 2016
The management of corticosteroid refractory immune reconstitution inflammatory syndrome (IRIS) is currently unclear. Infliximab administration was associated with clinical improvement without significant adverse events in 3 patients with mycobacterial ...
D. Hsu   +8 more
semanticscholar   +1 more source

3D‐cultured BMSC exosomes improve cerebral ischemia/reperfusion injury‐induced neuronal apoptosis by regulating the microglia polarization

open access: yesBMEMat, EarlyView.
The study reveals that microglial activation significantly contributes to neuroinflammation following cerebral ischemia‐reperfusion injury. It demonstrates that utilizing GelMA hydrogel for three‐dimensional culture of bone marrow‐derived mesenchymal stem cells (BMSCs) enhances the efficacy of BMSC‐derived exosomes in regulating microglial polarization
Yuming Li   +13 more
wiley   +1 more source

Hemophagocytic Syndrome Associated with Immune Reconstitution Inflammatory Syndrome in a Patient with AIDS Related Burkitt’s Leukemia/Lymphoma

open access: yesCase Reports in Medicine, 2014
Highly active antiretroviral therapy (HAART) has markedly decreased human immunodeficiency virus- (HIV-) related mortality and the incidence of opportunistic infections.
Metin Kanıtez   +5 more
doaj   +1 more source

Quantitative Cluster Headache Analysis for Neurological Diagnosis Support Using Statistical Classification

open access: yesInformation, 2020
Cluster headache (CH) belongs to the group III of The International Classification of Headaches. It is characterized by attacks of severe pain in the ocular/periocular area accompanied by cranial autonomic signs, including parasympathetic activation and ...
Mohammed El-Yaagoubi   +5 more
doaj   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

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