Results 61 to 70 of about 3,452,077 (357)

Effect of Electromagnetic Frequency on the Flow Behavior in Mold during Bloom Casting

open access: yesMetals, 2021
Considering solidification, a large eddy simulation (LES) model of two-phase flow was established to simulate the thermal–magnetic flow coupled fields inside a jumbo bloom.
Xianglong Li   +5 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Imaging interstitial iron concentrations in boron-doped crystalline silicon using photoluminescence [PDF]

open access: yes, 2016
Imaging the band-to-band photoluminescence of silicon wafers is known to provide rapid and high-resolution images of the carrier lifetime. Here, we show that such photoluminescence images, taken before and after dissociation of iron-boron pairs, allow an
Macdonald, D., Tan, J., Trupke, T.
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Elaboration of the Thermodynamic Model of Refining the Converter Bath when Blowing through Three-Tier Oxygen Lance [PDF]

open access: yesНаукові вісті Національного технічного університету України "Київський політехнічний інститут", 2017
Background. In modern conditions, the BOP-process is the main method of mass use steel product production. At the same time, due to the shortage of high-quality charge materials, resource and energy-saving technologies are particularly relevant.
Anatoliy G. Chernyatevich   +2 more
doaj   +1 more source

The in vitro assessment of the bioavailability of iron in New Zealand beef : a thesis presented in partial fulfillment of the requirements for the degree of Master of Science in Physiology at Massey University, Palmerston North, New Zealand / [PDF]

open access: yes, 2003
The bioavailability of iron in New Zealand beef either alone or as part of a 'typical' New Zealand meal was investigated. The solubility of iron and its in vitro absorption by mouse intestinal tissue were used to evaluate iron bioavailability.
Walker, Lisa Rochelle
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

NGBoost algorithm-based prediction of mechanical properties of a hot-rolled strip and its interpretability research with ANOVA values

open access: yesAIMS Mathematics
Hot-rolled strip steel is an essential material extensively used in various industrial fields, with its mechanical properties being critical to product quality and engineering design.
Hongyi Wu, Jinwen Jin , Zhiwei Li
doaj   +1 more source

Photoreductive Dissolution of Iron Oxides Trapped in Ice and Its Environmental Implications [PDF]

open access: yes, 2010
The availability of iron has been thought to be a main limiting factor for the productivity of phytoplankton and related with the uptake of atmospheric CO_2 and algal blooms in fresh and sea waters. In this work, the formation of bioavailable iron (Fe(II)
Choi, Wonyong   +4 more
core   +1 more source

Home - About - Disclaimer - Privacy