Results 61 to 70 of about 2,029,067 (346)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Anchoring zero valence single atoms of nickel and iron on graphdiyne for hydrogen evolution

open access: yesNature Communications, 2018
Electrocatalysis by atomic catalysts is a major focus of chemical and energy conversion effort. Although transition-metal-based bulk electrocatalysts for electrochemical application on energy conversion processes have been reported frequently, anchoring ...
Yurui Xue   +8 more
semanticscholar   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

INFLUENCE OF LOW-VOLTAGE ELECTRIC ENERGY ON FORMING OF SLAGS CHARACTERISTICS AT CASTING OF METAL IN CONVERTER

open access: yesЛитьë и металлургия, 2006
The considerable influence of electric effect on viscosity, surface tension and electrical conduction of the slag is determined and also the dependence of the character of these characteristics change on potential polarity is revealed.
V. F. Polakov   +4 more
doaj  

Synthesis, characterization, applications, and challenges of iron oxide nanoparticles

open access: yesNanotechnology, Science and Applications, 2016
Recently, iron oxide nanoparticles (NPs) have attracted much consideration due to their unique properties, such as superparamagnetism, surface-to-volume ratio, greater surface area, and easy separation methodology.
Attarad Ali   +6 more
semanticscholar   +1 more source

Erythropoietin and iron [PDF]

open access: yesKidney International, 1999
Serum ferritin concentration is most informative in estimating the amount of storage iron available for a particular individual. The serum transferrin receptor concentration, in contrast to serum ferritin, provides direct information about any deficit in the adequacy of iron supply to the erythropoiesis.
René Gottschalk   +1 more
openaire   +3 more sources

Identifying prognostic targets in metastatic prostate cancer beyond AR

open access: yesFEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng   +13 more
wiley   +1 more source

The ways of development of the technology and equipment for spirals coiling at production of steel piston rings of internal combustion engines

open access: yesЛитьë и металлургия, 2003
There are examined the peculiarities of the process of spiral winding for production of steel piston rings at using of new constructions of spiral-winding mashine-tools, working on one-thrust and two-thrust schemas of winding.
Ju. N. Golovanov   +4 more
doaj  

Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms

open access: yesNature, 2020
The serum level of iron in humans is tightly controlled by the action of the hormone hepcidin on the iron efflux transporter ferroportin. Hepcidin regulates iron absorption and recycling by inducing the internalization and degradation of ferroportin 1 ...
Christian B. Billesbølle   +9 more
semanticscholar   +1 more source

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