Results 81 to 90 of about 1,597,127 (300)
Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis
FEBS Open Bio, EarlyView.Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto +14 more
wiley +1 more source
Iron-Refractory Iron Deficiency Anemia
Seminars in Hematology, 2009 Iron-refractory iron deficiency anemia (IRIDA) is an autosomal recessive disorder characterized by iron deficiency anemia unresponsive to oral iron treatment but partially responsive to parenteral iron therapy. IRIDA has recently been shown to be caused by mutations in the gene TMPRSS6, which encodes a transmembrane serine protease (also known as ...
openaire +2 more sources
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
ASSIMILATION OF THE TECHNOLOGY OF ROLLING-AND-DRAGGING OF STEEL TAPE FOR PISTON RINGS
Литьë и металлургия, 2004 The trial approbation of the various technological circuits rolling-draged, has shown, that most efficient in conditions of rolling laboratory of Institute of black metallurgy is the technological circuit calibring of tapes with use of a priciple of ...
A. P. Lohmatov +4 more
doaj
The status of Chinese permanent magnet industry and R&D activities
AIP Advances, 2017 It has been 15 years since China dominated the rare earth permanent magnet market in 2001. The annual output of sintered Nd-Fe-B magnets in China reached a new record of 126,300 tonnages in 2015 while the output in 2001 is only 6,500 tonnages.
Shengzhi Dong +3 more
doaj +1 more source
, 1874 Title from caption.Issues "for the month ending" July 31, 1874-Mar. 31, 1879 also bear the publication date of the 10th of the following month. Vol. 29, no. 7-v. 31, no.
Iron Molders' Union of North America. +1 more
core
T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ±
Sarah J. Wright +10 more
wiley +1 more source
Литьë и металлургия, 2009 Retrospective analysis of dynamics investigation of high-speed wire rolled blocks, means and methods, applied for their diagnostics, is carried out.
S. M. Zhuchkov +4 more
doaj
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source