Results 41 to 50 of about 1,066,040 (298)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Increased iron deficiency and iron deficiency anemia in children with zinc deficiency

The Eurasian Journal of Medicine, 2017
Abstract   Objective: The aim of the present study is to determine the presence of iron (Fe) deficiency and Fe deficiency anemia in children with zinc (Zn) deficiency.   Materials and Methods: This retrospective study comprised 560 patients aged 6 months to 16 years in whom Zn levels in hair samples were measured concurrently with serum ...
KARAMAN, Serap, Ergul, Ayse Betul, Turanoglu, Cem, Torun, Yasemin Altuner, Karakukcu, ÇİĞDEM   +4 more
openaire   +3 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Evaluation of mineral and near-infrared forecasting of wheat yield varieties using spectrophotometric techniques [PDF]

Global Journal of Environmental Science and Management
BACKGROUND AND OBJECTIVE: Iron, an essential micronutrient, significantly contributes to growth, immune health, and cognitive development in human health. Inadequate dietary iron intake leads to iron deficiency anemia, affecting nearly 1.6 billion people,
H.A. Pardhe, N. Krishnaveni, B.K. Chekraverthy, S. Patel, S. Naveen, V. Rashmi, P.C. Govinden   +6 more
doaj   +1 more source

Lack of iron, zinc, and vitamins as a contributor to the etiology of atopic diseases

Frontiers in Nutrition, 2023
Micronutritional deficiencies are common in atopic children suffering from atopic dermatitis, food allergy, rhinitis, and asthma. A lack of iron, in particular, may impact immune activation with prolonged deficiencies of iron, zinc, vitamin A, and ...
Diego G. Peroni, Karin Hufnagl, Karin Hufnagl, Pasquale Comberiati, Franziska Roth-Walter, Franziska Roth-Walter   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in 884 patients with burning mouth syndrome

Journal of the Formosan Medical Association, 2020
Background/Purpose: Burning mouth syndrome (BMS) is characterized by burning sensation of the oral mucosa in the absence of clinically apparent oral mucosal alterations.
Chun-Pin Chiang, Yu-Hsueh Wu, Yang-Che Wu, Julia Yu-Fong Chang, Yi-Ping Wang, Andy Sun   +5 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

HbA1c Levels in Controlled Diabetics with and without Iron Deficiency Anemia: A Tertiary Care Experience [PDF]

Journal of Basic Research in Medical Sciences
Introduction: Glycated hemoglobin (HbA1c) is widely used to assess long-term glycemic control in diabetic patients. However, non-glycemic factors such as iron deficiency anemia (IDA) may alter HbA1c levels, potentially affecting its accuracy.
Zoya Khatri, Anita Chalak, Megha Bangar, Shalini Maksane, Supriya Khillare   +4 more
doaj