Results 121 to 130 of about 50,429 (161)
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Clinics in Liver Disease, 2002
Because hepatic siderosis is a frequent finding, there is a risk of making it trite when elaborating the pathology report. Iron is increasingly considered an important cofactor of morbidity. Its finding in hepatic cells must be recognized, indicated, qualified, quantified, and interpreted.
Bruno, Turlin, Yves, Deugnier
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Because hepatic siderosis is a frequent finding, there is a risk of making it trite when elaborating the pathology report. Iron is increasingly considered an important cofactor of morbidity. Its finding in hepatic cells must be recognized, indicated, qualified, quantified, and interpreted.
Bruno, Turlin, Yves, Deugnier
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New England Journal of Medicine, 2013
Both hemochromatosis and β-thalassemia are caused by a deficiency of hepcidin, which represses expression of ferroportin at the surface of cells that export iron into the blood. Studies suggest that repressing expression of a hepcidin inhibitor ameliorates disease in mouse models.
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Both hemochromatosis and β-thalassemia are caused by a deficiency of hepcidin, which represses expression of ferroportin at the surface of cells that export iron into the blood. Studies suggest that repressing expression of a hepcidin inhibitor ameliorates disease in mouse models.
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Acta Paediatrica, 1989
Halliday, J. W. (The Liver Group, Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia). Inherited iron overload.Several inherited forms of iron overload have been described. It is now accepted that HC, usually regarded as a disease of adult life, is an inherited disorder, hence all first degree relatives must ...
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Halliday, J. W. (The Liver Group, Department of Medicine, University of Queensland, Royal Brisbane Hospital, Brisbane, Australia). Inherited iron overload.Several inherited forms of iron overload have been described. It is now accepted that HC, usually regarded as a disease of adult life, is an inherited disorder, hence all first degree relatives must ...
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Hematology, 2001
Abstract Transfusion therapy for inherited anemias and acquired refractory anemias both improves the quality of life and prolongs survival. A consequence of chronic transfusion therapy is secondary iron overload, which adversely affects the function of the heart, the liver and other organs.
J P, Kushner, J P, Porter, N F, Olivieri
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Abstract Transfusion therapy for inherited anemias and acquired refractory anemias both improves the quality of life and prolongs survival. A consequence of chronic transfusion therapy is secondary iron overload, which adversely affects the function of the heart, the liver and other organs.
J P, Kushner, J P, Porter, N F, Olivieri
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Seminars in Hematology, 2002
Iron overload is common in rural sub-Saharan African populations that have the custom of drinking a traditional fermented beverage with high iron content. As with both excessive alcohol exposure and HFE hemochromatosis, hepatic portal fibrosis and micronodular cirrhosis are prominent sequelae of African iron overload.
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Iron overload is common in rural sub-Saharan African populations that have the custom of drinking a traditional fermented beverage with high iron content. As with both excessive alcohol exposure and HFE hemochromatosis, hepatic portal fibrosis and micronodular cirrhosis are prominent sequelae of African iron overload.
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Clinical Toxicology, 1971
The human body exerts considerable control over iron absorption. This control is very essential since a small amount of this element is lost in the urine or through the gastrointestinal tract [ 11 . Under normal conditions the regulatory mechanism is adequate to maintain a state of iron balance.
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The human body exerts considerable control over iron absorption. This control is very essential since a small amount of this element is lost in the urine or through the gastrointestinal tract [ 11 . Under normal conditions the regulatory mechanism is adequate to maintain a state of iron balance.
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The Detection of Iron Overload
New England Journal of Medicine, 1982Human physiology is such that few people accumulate excess iron. Indeed, normal persons are able to control the accumulation of body iron despite ingestion of up to 5 to 10 times the normal amount.1 There are, however, two disorders in which large amounts of iron accumulate in the parenchymal cells.
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Blood, 2009
Abstract In a remarkable study in this issue of Blood, Lok and colleagues describe the genotypic and phenotypic characteristics of hereditary hemochromatosis in 42 cases in 8 distinct families of Asian origin ...
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Abstract In a remarkable study in this issue of Blood, Lok and colleagues describe the genotypic and phenotypic characteristics of hereditary hemochromatosis in 42 cases in 8 distinct families of Asian origin ...
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Postgraduate Medicine, 1973
The variable criteria used in diagnosing hemochromatosis have resulted in considerable confusion in the literature. How does one separate the alcoholic with cirrhosis and secondary iron overload from the patient with “familial hemochromatosis” who happens to drink too much? And if phlebotomy is the way to treat hemochromatosis, why not use this therapy
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The variable criteria used in diagnosing hemochromatosis have resulted in considerable confusion in the literature. How does one separate the alcoholic with cirrhosis and secondary iron overload from the patient with “familial hemochromatosis” who happens to drink too much? And if phlebotomy is the way to treat hemochromatosis, why not use this therapy
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