Results 51 to 60 of about 541,303 (310)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Anti-radical, anti-inflammatory and antibacterial efficacy of iron oxide nanoparticles availed using aqueous extract of Vitex trifolia leaf

Next Materials
Nanotechnology creates nanometric particles with new and improved traits. In our work, we created iron oxide nanoparticles using the aqueous extrac`t of V. trifolia (Vitex trifolia) leaf.
S.L. Harish, Dhivya Viswanathan, Rajakumar Govindasamy, B. Nisha   +3 more
doaj   +1 more source

Boron Removal by Adsorption onto Different Oxides

Journal of Engineering, 2023
A research was conducted to determine the feasibility of using adsorption process to remove boron from aqueous solutions using batch technique. Three adsorbent materials; magnesium, aluminum and iron oxide were investigated to find their abilities for ...
Abbas, H. Sulaymoon, Saadi, K. Al-Naseri, Ibtihal, A.Jabbar, A. Qader   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Photoreductive Dissolution of Iron Oxides Trapped in Ice and Its Environmental Implications [PDF]

, 2010
The availability of iron has been thought to be a main limiting factor for the productivity of phytoplankton and related with the uptake of atmospheric CO_2 and algal blooms in fresh and sea waters. In this work, the formation of bioavailable iron (Fe(II)
Choi, Wonyong, Hoffmann, Michael R., Kim, Kitae, Park, Byong-Kwon, Yoon, Ho-Il   +4 more
core   +1 more source

Superparamagnetic particles in ZSM-5-type ferrisilicates [PDF]

, 2008
As-synthesized, low iron content, ferrisilicates of ZSM-5-type contain well-separated Fe(III) ions in a tetrahedral environment and display paramagnetic behavior.
Corma, A, GarciaPalacios, JL, Larrea, A, Lazaro, FJ, Lopez, A, Martinez, C, Pankhurst, QA   +6 more
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Synthesis and characterization of iron and iron nitride microtubes obtained from biogenic iron oxide [PDF]

, 2017
With the aim to obtain iron tubular microstructures attractive for various applications, we have used a natural biogenic iron ochre as a raw material and explore various procedures and experimental conditions to achieve our goal. Our experiments included
Hargreaves, J.S.J., Rico, J.L.
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

MRI-monitored intra-tumoral injection of iron-oxide labeled Clostridium novyi-NT anaerobes in pancreatic carcinoma mouse model. [PDF]

PLoS ONE, 2014
To validate the feasibility of labeling Clostridium novyi-NT (C.novyi-NT) anaerobes with iron-oxide nanoparticles for magnetic resonance imaging (MRI) and demonstrate the potential to use MRI to visualize intra-tumoral delivery of these iron-oxide ...
Linfeng Zheng, Zhuoli Zhang, Khashayarsha Khazaie, Saurabh Saha, Robert J Lewandowski, Guixiang Zhang, Andrew C Larson   +6 more
doaj   +1 more source