Results 1 to 10 of about 388,326 (204)

Divalent metal transporter 1 (DMT1) in the brain: Implications for a role in iron transport at the blood-brain barrier, and neuronal and glial pathology [PDF]

Frontiers in Molecular Neuroscience, 2015
Iron is required in a variety of essential processes in the body. In this review, we focus on iron transport in the brain and the role of the divalent metal transporter 1 (DMT1) vital for iron uptake in most cells.
Torben eMoos
doaj   +5 more sources

Residual erythropoiesis protects against myocardial hemosiderosis in transfusion-dependent thalassemia by lowering labile plasma iron via transient generation of apotransferrin [PDF]

Haematologica, 2017
Cardiosiderosis is a leading cause of mortality in transfusion-dependent thalassemias. Plasma non-transferrin-bound iron and its redox-active component, labile plasma iron, are key sources of iron loading in cardiosiderosis.
Maciej W. Garbowski, Patricia Evans, Evangelia Vlachodimitropoulou, Robert Hider, John B. Porter   +4 more
doaj   +3 more sources

Fob1 and Fob2 Proteins Are Virulence Determinants of Rhizopus oryzae via Facilitating Iron Uptake from Ferrioxamine. [PDF]

PLoS Pathogens, 2015
Dialysis patients with chronic renal failure receiving deferoxamine for treating iron overload are uniquely predisposed for mucormycosis, which is most often caused by Rhizopus oryzae.
Mingfu Liu, Lin Lin, Teclegiorgis Gebremariam, Guanpingsheng Luo, Christopher D Skory, Samuel W French, Tsui-Fen Chou, John E Edwards, Ashraf S Ibrahim   +8 more
doaj   +4 more sources

Akkermansia muciniphila MucT harnesses dietary polyphenols as xenosiderophores for enhanced iron uptake [PDF]

Nature Communications
Dietary proanthocyanidins (PACs) are polyphenols that promote a healthy gut microbiome. PACs are notable for their rich catechol moieties with high affinity for iron, enabling them to interfere with pathogens’ iron uptake.
Maria-Carolina Rodríguez-Daza, Sjef Boeren, Hanne L. P. Tytgat, Yves Desjardins, Willem M. de Vos   +4 more
doaj   +2 more sources

Study in the iron uptake mechanism of Pasteurella multocida [PDF]

Veterinary Research
Pasteurella multocida infects a wide range of animals, causing hemorrhagic septicemia or infectious pneumonia. Iron is an essential nutrient for growth, colonization, and proliferation of P.
Xiangxiang Shen, Lijun Guan, Junfeng Zhang, Yun Xue, Lifang Si, Zhanqin Zhao   +5 more
doaj   +2 more sources

Type VII secretion system deploys an active iron uptake pathway to enhance bacterial fitness and counteract host nutritional immunity [PDF]

mBio
Type VII secretion systems (T7SS) are increasingly recognized as pivotal for bacterial adaptation across both environmental and host-associated niches in Gram-positive bacteria.
Chunhui Luo, Xinwei Hao, Xiao Wang, Mohua Liu, Shukun Chen, Conghui Wu, Chen Li, Can Chen, Mingming Yang, Lei Xu, Yao Wang, Xihui Shen   +11 more
doaj   +2 more sources

Structural determination of mugineic acid, an iron(III)-chelating substance secreted from graminaceous plants for efficient iron uptake [PDF]

Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
Iron is an essential element for organisms, but its solubility in soil is often extremely low. Previously, plants were considered to take up iron only after its reduction to ferrous ions.
Takanori KOBAYASHI, Naoko K.NISHIZAWA
doaj   +2 more sources

Repurposing of FDA-Approved Drugs to Disrupt Iron Uptake in Mycobacterium abscessus: Targeting Salicylate Synthase as a Novel Approach. [PDF]

Chem Biol Drug Des
Stelitano G, Bettoni C, Mori M, Cocorullo M, Tresoldi A, Meneghetti F, Villa S, Chiarelli LR.   +7 more
europepmc   +3 more sources

N<i>-</i>acetyltransferases required for iron uptake and aminoglycoside resistance promote virulence lipid production in <i>Mycobacterium marinum</i>. [PDF]

Proc Natl Acad Sci U S A
Jones BS, Pareek V, Hu DD, Weaver SD, Syska C, Galfano G, Champion MM, Champion PA.   +7 more
europepmc   +2 more sources

Baseline ferritin predicts myocardial iron uptake following intravenous iron therapy- a hypothesis generating study [PDF]

Nunez J, Mollar A, Vera-Aviles M, Kabir S, Shah A, Polzella P, Desborough M, Cardells I, Miñana G, del Canto I, Ferreira V, Piechnik S, Maceira A, Lakhal-Littleton S.   +13 more
europepmc   +2 more sources