Results 71 to 80 of about 388,475 (351)
Iron Homeostasis in Azotobacter vinelandii
Biology, 2023 Iron is an essential nutrient for all life forms. Specialized mechanisms exist in bacteria to ensure iron uptake and its delivery to key enzymes within the cell, while preventing toxicity.
Elena Rosa-Núñez +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Enterobacter bugandensis: a novel enterobacterial species associated with severe clinical infection [PDF]
, 2018 Nosocomial pathogens can cause life-threatening infections in neonates and immunocompromised patients. E. bugandensis (EB-247) is a recently described species of Enterobacter, associated with neonatal sepsis.
Bunk, Boyke +20 more
core +2 more sources
ABCs of erythroid mitochondrial iron uptake [PDF]
Proceedings of the National Academy of Sciences, 2009 ATP-binding cassette (ABC) transporter proteins are present in all known species, serving a variety of important functions that generally involve translocation of small molecules across cellular membranes (1). In this issue of PNAS, Chen et al.
openaire +2 more sources
Iron uptake in Plesiomonas shigelloides: cloning of the genes for the heme-iron uptake system [PDF]
Infection and Immunity, 1991 The iron uptake systems of Plesiomonas shigelloides strains were determined. Siderophore production was not detected by chemical or biological assays, and the strains tested were unable to use enterobactin, aerobactin, or vibriobactin for growth in low-iron media.
P A, Daskaleros +2 more
openaire +2 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Iron Acquisition Strategies of Vibrio anguillarum
Frontiers in Cellular and Infection Microbiology, 2017 The hemorrhagic septicemic disease vibriosis caused by Vibrio anguillarum shows noticeable similarities to invasive septicemia in humans, and in this case, the V.
Yingjie Li +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Veterinary Research, 2020 Avian pathogenic Escherichia coli (APEC), a pathotype of extraintestinal pathogenic E. coli, causes one of the most serious infectious diseases of poultry and shares some common virulence genes with neonatal meningitis-associated E. coli.
Zhonghua Zhang +12 more
doaj +1 more source
Assessment of iron bioavailability from different bread making processes using an in vitro intestinal cell model [PDF]
, 2017 Myo-inositol hexakisphosphate (IP6), is the main iron chelator in cereals and bread. The aim of this study was to investigate the effect of three commercial baking processes (sourdough, conventional yeast and Chorleywood Bread Making Process (CBP)) on ...
A. Perfecto +40 more
core +2 more sources