Results 91 to 100 of about 139,657 (337)

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló   +5 more
wiley   +1 more source

The hazards of using IRR to measure performance: The case of private equity

open access: yes, 2008
Most of the investments in asset classes such as real estate and private equity (include buyout, mezzanine and venture capital) are made via private partnerships. Measuring performance in these partnerships is important for investment allocation decision
Phalippou, Ludovic
core  

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

RESISTENSI TANAMAN KARET KLON IRR SERI 300 TERHADAP PENYAKIT GUGUR DAUN CORYNESPORA [PDF]

open access: yes, 2018
Penyakit gugur daun Corynespora yang disebabkan oleh cendawan Corynespora cassiicola (C. cassiicola) merupakan salah satu penyakit daun penting yang dapat menyebabkan penurunan produksi lateks pada perkebunan karet.
Syafaah, Afdholiatus   +2 more
core   +2 more sources

Profitability of venture capital investment in Europe and the United States [PDF]

open access: yes
This paper examines the profitability of venture capital investment in Europe and the United States. It highlights the unfavourable profitability differential of European venture capital investment in comparison with the United States.
Kristiina Raade   +1 more
core  

Do drugs approved via expedited approval pathways have therapeutic advantages? A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Regulators use expedited approval pathways to speed market approval and patient access to promising new drugs. However, there is uncertainty about whether these pathways are successful in approving drugs with significant therapeutic advantages. This systematic review aims to examine the safety, effectiveness and cost‐effectiveness of drugs approved via
Ashleigh Hooimeyer   +4 more
wiley   +1 more source

Predictors of authorised, unauthorised and persistent absence among secondary school pupils in Scotland

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This article examines the factors associated with persistent absenteeism (an absence rate of 10% or higher) and authorised and unauthorised absence among secondary school pupils in Scotland. Using linked administrative data, the analysis focuses on secondary school stages S1–S6 in three academic years.
Silvia Behrens   +6 more
wiley   +1 more source

Colorectal cancer statistics, 2017

open access: yesCa, 2017
Colorectal cancer (CRC) is one of the most common malignancies in the United States. Every 3 years, the American Cancer Society provides an update of CRC incidence, survival, and mortality rates and trends.
R. Siegel   +6 more
semanticscholar   +1 more source

Economic and accounting rates of return [PDF]

open access: yes
The rate of return on invested capital is a central concept in financial analysis. The purpose of calculating the rate of return on investment in general is to measure the financial performance, to assess the desirability of a project and to make ...
Feenstra, D.W., Wang, H.
core  

IRR of PD adjusted for potential confounders.

open access: yes, 2015
* Main analysis: IRR for the association between GTZ use and incident PD using conditional Poisson regression to control for gender, age, practice, and treatment stageIRR of PD adjusted for potential confounders.
Ruth Brauer (773591)   +5 more
core   +1 more source

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