Results 1 to 10 of about 179,498 (360)
Systems‐wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation
Molecular Systems Biology, 2015 B‐cell receptor (BCR) signaling is essential for the development and function of B cells; however, the spectrum of proteins involved in BCR signaling is not fully known. Here we used quantitative mass spectrometry‐based proteomics to monitor the dynamics
Shankha Satpathy +2 more
exaly +3 more sources
Bcr: a negative regulator of the Bcr-Abl oncoprotein [PDF]
Oncogene, 1999 Chronic myelogenous leukemia is typically characterized by the presence of the Philadelphia chromosome (Ph) in which 5' portions of the BCR gene are fused to a large portion of the ABL gene. Our studies and those of others indicate that Bcr sequences within the Bcr-Abl oncoprotein are critically involved in activating the Abl tyrosine kinase and ...
Yun Wu, Hong-Ji Xu, Ralph B Arlinghaus
exaly +3 more sources
Response and Resistance to BCR-ABL1-Targeted Therapies
Cancer Cell, 2020 Chronic myeloid leukemia (CML), caused by constitutively active BCR-ABL1 fusion tyrosine kinase, has served as a paradigm for successful application of molecularly targeted cancer therapy.
Theodore P Braun +2 more
exaly +2 more sources
Gastrointestinal Disorders, 2022 Background: During the COVID-19 pandemic, the Flemish colorectal cancer (CRC) screening program (by fecal immunochemical test, FIT) was suspended and non-urgent medical procedures were discommended.
Sarah Hoeck +3 more
doaj +1 more source
Synthesis of Low TENORM Zirconium Sulfate from ZrO(OH)2 with Sulfuric Acid
Indonesian Journal of Chemistry, 2021 Zirconium sulfate (ZS) has become one of the alternative chemical compounds for substituting traditional tannery substances using chromium(III) which was not environmentally friendly.
Rahmatika Alfia Amliliana +1 more
doaj +1 more source
Pharmaceutics, 2022 The constitutively active BCR-ABL1 tyrosine kinase, found in t(9;22)(q34;q11) chromosomal translocation-derived leukemia, initiates an extremely complex signaling transduction cascade that induces a strong state of resistance to chemotherapy.
G. Amarante-Mendes +4 more
semanticscholar +1 more source
Immune repertoire: Revealing the “real-time” adaptive immune response in autoimmune diseases
Autoimmunity, 2021 The diversity of the immune repertoire (IR) enables the human immune system to distinguish multifarious antigens (Ags) that humans may encounter throughout life.
Meiyu Wu +3 more
doaj +1 more source
Jurnal HPT (Hama Penyakit Tumbuhan), 2021 Rekayasa ekologi melalui manipulasi habitat merupakan bentuk konservasi ekologi yang bertujuan melestarikan keberadaan musuh alami, salah satunya golongan predator generalis.
Muhammad Nawab al Hasan +2 more
doaj +1 more source
Cogent Food & Agriculture, 2021 The study employed cost-return analysis, Cobb-Douglas production function and marginal value product-marginal factor cost (MVP-MFC) approach to estimate and analyze profitability, productivity and resource use efficiency, respectively, of banana ...
Manoj Sharma +3 more
doaj +1 more source
Profitability analysis of cut flower cultivation in Bangladesh: Constraints and opportunities
International Journal of Agricultural Research, Innovation and Technology, 2023 Bangladesh has immense potential for cut flower production and export to the world market. Although the export earnings from cut flower cultivation are gradually increasing in our country, production and profitability are hindered by some constraints ...
Md Imrul Kaysar +4 more
doaj +1 more source