Results 41 to 50 of about 109,902 (263)

Using R In Generalized Linear Models [PDF]

Revista Română de Statistică, 2015
This paper aims to approach the estimation of generalized linear models (GLM) on the basis of the glm routine package in R. Particularly, regression models will be analyzed for those cases in which the explained variable follows a Poisson or a Negative ...
Mihaela Covrig, Iulian Mircea, Gheorghiţă Zbăganu, Alexandru Coşer, Alexandru Tindeche   +4 more
doaj  

3D‐Nanoprinted Fluidically Steerable Soft Robotic Microcatheters

Advanced Robotics Research, EarlyView.
This work introduces a ∼3‐French (1 mm‐in‐diameter) soft robotic microcatheter fabricated by means of two‐photon direct laser writing. The 3D‐printed microcatheter enables remote, on‐demand steering via microfluidic actuation for guidewire‐free navigation of vascular networks as well as microcatheter‐mediated delivery of fluidic payloads to target ...
Bailey M. Felix, Molly Carton, Olivia M. Young, Noah Barnes, Jordi T. Andreou, Sarah McHugh, Jack E. McCann, Claudia Davis, Victoria Reddig‐Leiman, Afsah Kamran, Dheeraj Gandhi, Miroslaw Janowski, Jeremy D. Brown, Mark Fuge, Axel Krieger, Clifford R. Weiss, Christopher R. Bailey, Ryan D. Sochol   +17 more
wiley   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang, Yi Wang, Xiaohang Lu, Qianlan Yao, Libing Xiang, Xu Cai, Xiaoyu Tu, Shaoxian Tang, Ying Xu, Yufan Cheng, Liming Shen, Huijuan Yang   +11 more
wiley   +1 more source

Application of the Böhm chamber for reference beta dose measurements and the calibration of personal dosimeters

Nukleonika, 2016
Thermoluminescent dosimeters (TLDs) currently used in personal and area dosimetry are often utilized to measure doses of ionizing radiation in fields with a more complex structure and therefore they should be calibrated in relation to different radiation
Skubacz Krystian
doaj   +1 more source

Validation of a Drosophila model of wild-type and T315I mutated BCR-ABL1 in chronic myeloid leukemia: an effective platform for treatment screening

Haematologica, 2020
Chronic myeloid leukemia (CML) is caused by a balanced chromosomal translocation resulting in the formation of BCR-ABL1 fusion gene encoding a constitutively active BCR-ABL1 tyrosine kinase, which activates multiple signal transduction pathways leading ...
Amani Al Outa, Dana Abubaker, Ali Bazarbachi, Marwan El Sabban, Margret Shirinian, Rihab Nasr   +5 more
doaj   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source

Antibody repertoire sequencing analysis

Acta Biochimica et Biophysica Sinica, 2022
High-throughput sequencing for B cell receptor (BCR) repertoire provides useful insights for the adaptive immune system. With the continuous development of the BCR-seq technology, many efforts have been made to develop methods for analyzing the ever ...
Zhang Senxin, Yang Tiange, Liu Xiaojing, Yang Jiyuan, Zheng Xiaoqi   +4 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Urinary exosomal microRNA profiling in intermediate-risk prostate cancer

Scientific Reports, 2021
MicroRNAs (miRNAs) of urine exosomes have emerged as biomarkers for urological cancers, owing to their high stability. MiRNAs have been linked to factors associated with aggressive prostate cancer such as biochemical recurrence (BCR) and metastasis.
Mee Young Kim, Hyunwoo Shin, Hyong Woo Moon, Yong Hyun Park, Jaesung Park, Ji Youl Lee   +5 more
doaj   +1 more source

BCR ubiquitination controls BCR-mediated antigen processing and presentation

Blood, 2006
AbstractBCR-mediated antigen processing occurs at immunologically relevant antigen concentrations and hinges on the trafficking of antigen-BCR (Ag-BCR) complexes to class II–containing multivesicular bodies (MVBs) termed MIICs. However, the molecular mechanism underlying the trafficking of Ag-BCR complexes to and within MIICs is not well understood. In
Lisa, Drake, Erica M, McGovern-Brindisi, James R, Drake   +2 more
openaire   +3 more sources