Results 61 to 70 of about 5,171 (202)

ITER materials irradiation within the D–T neutron environment at JET: post-irradiation radioactivity analysis following the DTE2 experimental campaign

Nuclear Fusion
This work presents the results following the first irradiation of ITER materials samples in a tokamak D–T plasma environment operating at significant fusion power.
L.W. Packer, P. Batistoni, C. Bearcroft, S.C. Bradnam, E. Eardley, M. Fabbri, N. Fonnesu, M.R. Gilbert, Z. Ghani, K. Gorzkiewicz, C.L. Grove, R. Kierepko, E. Łaszyńska, I. Lengar, X. Litaudon, S. Loreti, J.W. Mietelski, M. Pillon, M.I. Savva, C.R. Shand, I.E. Stamatelatos, A.N. Turner, T. Vasilopoulou, R. Villari, A. Wójcik-Gargula, A. Žohar, JET Contributors   +26 more
doaj   +1 more source

Structured sorbents for Direct Air Capture: The impact of materials and chemicals on performance

AIChE Journal, EarlyView.
Abstract Structured sorbents can efficiently process large air volumes required for Direct Air Capture (DAC), but their broad implementation is limited by challenges in producing reproducible and homogeneous materials. This work presents a robust procedure to graft amines onto monolithic sorbents and systematically investigates how CO2$$ {\mathrm{CO ...
Nicole Ferru, Moritz Bischof, Martina Saporito, David Büchner, Quirin Grossmann, Vincent Dufour‐Décieux, Ronny Pini, André Bardow, Marco Mazzotti   +8 more
wiley   +1 more source

Photochemical Reaction Discovery Enabled by the Dynamic Speciation of Copper Complexes

Angewandte Chemie, EarlyView.
A strategy for accelerated photochemical reaction discovery is reported that harnesses the dynamic speciation of copper complexes, driven by their labile metal–ligand bonds. This platform simplifies reaction screening by combining an earth‐abundant copper(II) salt with commercially available ligands, which reversibly generate multiple catalytic species
Alessio Regni, Siyu Liang, Supreeta Sen, Hailey Hendricks, Xijue Wu, Matthew V. Pecoraro, Jose B. Roque   +6 more
wiley   +2 more sources

Data‐Guided Photocatalysis: Supervised Machine Learning in Water Splitting and CO2 Conversion

Advanced Intelligent Discovery, EarlyView.
This review highlights recent advances in supervised machine learning (ML) for photocatalysis, emphasizing methods to optimize photocatalyst properties and design materials for solar‐driven water splitting and CO2 reduction. Key applications, challenges, and future directions are discussed, offering a practical framework for integrating ML into the ...
Paul Rossener Regonia, Christian Mark Pelicano   +1 more
wiley   +1 more source

Borylcyclopropanes: Synthetic Strategies and Applications

Angewandte Chemie, EarlyView.
Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley   +2 more sources

FastCat: Autonomous Discovery of Multielement Layered Double Hydroxide Alloy Catalysts for Alkaline Oxygen Evolution Reaction

Advanced Intelligent Discovery, EarlyView.
A machine learning‐guided self‐driving laboratory screened over 500 nickel‐based layered double‐hydroxide catalysts for alkaline oxygen evolution. Out of the eight metals, the robot uncovered a quaternary Ni–Fe–Cr–Co catalysts requiring only 231 mV overpotential to reach 20 mA cm−2.
Nis Fisker‐Bødker, Enzo Raffaele Moretti, Jin Hyun Chang, Tejs Vegge   +3 more
wiley   +1 more source

A Modular Synthesis of C5‐Sulfenyl Thiazoles via an Intermolecular Pummerer Rearrangement: An Underexplored Scaffold for Medicinal Chemistry

Angewandte Chemie, EarlyView.
Modular access to underexplored C5‐sulfenyl thiazoles via an intermolecular Pummerer rearrangement is reported. The methodology exhibits a broad functional group tolerance enabling the seamless design of trisubstituted thiazole cores bearing a sulfur handle for further elaboration.
Joe L. Smy, Theo C. Webb, Barnaby W. Greenland, S. Mark Roe, John Spencer, Storm Hassell‐Hart   +5 more
wiley   +2 more sources

Accelerating Discovery of Organic Molecular Crystals via Materials Informatics and Autonomous Experiments

Advanced Intelligent Discovery, EarlyView.
Materials informatics and autonomous experimentation are transforming the discovery of organic molecular crystals. This review presents an integrated molecule–crystal–function–optimization workflow combining machine learning, crystal structure prediction, and Bayesian optimization with robotic platforms.
Takuya Taniguchi, Kazuki Ishizaki, Ryo Fukasawa   +2 more
wiley   +1 more source

A Comprehensive 19F NMR Framework for Fragment‐Based Drug Discovery: The Validated Screening Library OpenFL600 and Efficient Affinity Ranking by CSAR

Angewandte Chemie, EarlyView.
NMR screening is a powerful method for hit detection in drug‐discovery. We designed and validated the OpenFL600 19F$^{19}{\rm F}$ NMR library to probe diverse targets, including RNA, GPCRs, kinases, and proteases. This library yields target‐specific ligands without generating promiscuous binders.
Simon H. Rüdisser, Gabriela Stadler, Giacomo Padroni, Daria Barbash, Marco M. Ruckstuhl, Nils Lorz, Christina Jordan, Sarah Skibinski, Timo T. Stühlinger, Sarah E. Kratzwald, Katharina M. Siess, Sven Brüschweiler, Gerald Platzer, Antoine Cléry, Robert Konrat, Frédéric H.‐.T. Allain, Alvar D. Gossert   +16 more
wiley   +2 more sources

Beam impact tests of a prototype target for the beam dump facility at CERN: Experimental setup and preliminary analysis of the online results

Physical Review Accelerators and Beams, 2019
The beam dump facility (BDF) is a project for a new facility at CERN dedicated to high intensity beam dump and fixed target experiments. Currently in its design phase, the first aim of the facility is to search for light dark matter and hidden sector ...
E. Lopez Sola, M. Calviani, O. Aberle, C. Ahdida, P. Avigni, M. Battistin, L. Bianchi, S. Burger, J. Busom Descarrega, J. Canhoto Espadanal, E. Cano-Pleite, M. Casolino, M. A. Fraser, S. Gilardoni, S. Girod, J-L. Grenard, D. Grenier, M. Guinchard, C. Hessler, R. Jacobsson, M. Lamont, A. Ortega Rolo, M. Pandey, A. Perillo-Marcone, B. Riffaud, V. Vlachoudis, L. Zuccalli   +26 more
doaj   +1 more source