Results 111 to 120 of about 94,492 (293)

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner   +14 more
wiley   +1 more source

The Exergy Costs of Electrical Power, Cooling, and Waste Heat from a Hybrid System Based on a Solid Oxide Fuel Cell and an Absorption Refrigeration System

open access: yesEnergies, 2019
This paper applies the Exergy Cost Theory (ECT) to a hybrid system based on a 500 kWe solid oxide fuel cell (SOFC) stack and on a vapor-absorption refrigeration (VAR) system. To achieve this, a model comprised of chemical, electrochemical, thermodynamic,
V. H. Rangel-Hernandez   +3 more
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

open access: yesArthritis Care &Research, EarlyView.
Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo   +88 more
wiley   +1 more source

Ground state entanglement in quantum spin chains [PDF]

open access: yes, 2003
A microscopic calculation of ground state entanglement for the XY and Heisenberg models shows the emergence of universal scaling behavior at quantum phase transitions. Entanglement is thus controlled by conformal symmetry.
Latorre, J. I., Rico, E., Vidal, G.
core   +1 more source

Diagnostic Use of Testing for Novel Murine Autoantibodies for Sjögren Disease in the Rheumatology Outpatient Setting

open access: yesArthritis Care &Research, EarlyView.
Objective The goal was to assess the diagnostic performance of three novel autoantibodies (NA) for Sjögren disease (SjD) by comparing NA prevalence in patients with SjD, other autoimmune rheumatic diseases (ARDs), nonspecific chronic sialadenitis (CS), and controls.
Chadwick R. Johr   +5 more
wiley   +1 more source

Two Conceptions of Irreversible Environmental Harm [PDF]

open access: yes
The concept of "irreversibility" plays a large role in the theory and practice of environmental protection. Indeed, the concept is explicit in some statements of the Precautionary Principle. But the idea of irreversibility remains poorly defined. Because
Sunstein, Cass R.
core   +1 more source

Risk of Retinopathy Associated with Long‐Term Use of Hydroxychloroquine in Patients with Rheumatic Diseases: A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to estimate the prevalence and cumulative incidence of hydroxychloroquine retinopathy (HCQ‐R) and its risk factors among patients receiving long‐term HCQ with rheumatic diseases through a systematic review and meta‐analysis of observational studies that used spectral‐domain optical coherence tomography (SD‐OCT) for screening ...
Narsis Daftarian   +4 more
wiley   +1 more source

Thermodynamic Hamiltonian and Entropy Production

open access: yesMathematics
The variational method holds considerable significance within mathematical and theoretical physics. Its importance stems from its capacity to characterise natural systems through physical quantities, irrespective of the chosen frame of reference.
Umberto Lucia, Giulia Grisolia
doaj   +1 more source

Investment, irreversibility, and financing constraints in transition economies [PDF]

open access: yes
Using a panel of 4223 Bulgarian, Czech, Polish, and Romanian firms, over the period 1998-2005, we show that financially constrained firms likely to face irreversibility constraints exhibit low and insignificant sensitivities of investment to cash flow ...
Alessandra Guariglia   +2 more
core  

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

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