Results 241 to 250 of about 22,432 (259)
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Anesthesia & Analgesia, 2010
Bioelectrics, an interesting new area of medicine, combines pulsed high-voltage engineering with cell biology and has many potential applications. Pulsed electric current can be used to produce irreversible electroporation (IRE) of cell membranes with resulting cell death.
Christine, Ball +2 more
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Bioelectrics, an interesting new area of medicine, combines pulsed high-voltage engineering with cell biology and has many potential applications. Pulsed electric current can be used to produce irreversible electroporation (IRE) of cell membranes with resulting cell death.
Christine, Ball +2 more
openaire +3 more sources
Irreversible Electroporation Applications
2021In veterinary medicine, irreversible electroporation (IRE) applications have been evaluated in several early phase clinical trials evaluating the safety and feasibility of treatment of solid tumors located within different organ systems. These clinical trials support the use of IRE as a safe and effective alternative treatment option for tumors that ...
Brittanie Partridge +4 more
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Niche Applications of Irreversible Electroporation
Techniques in Vascular and Interventional Radiology, 2015Irreversible electroporation (IRE) induces cell death by exposing it to high-voltage, low-energy DC current pulses. The mechanism of cell death and healing is a departure from the other existing technologies such as radiofrequency ablation, microwave ablation, and cryoablation.
Shivank S, Bhatia +2 more
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Tissue Ablation with Irreversible Electroporation
Annals of Biomedical Engineering, 2005This study introduces a new method for minimally invasive treatment of cancer-the ablation of undesirable tissue through the use of irreversible electroporation. Electroporation is the permeabilization of the cell membrane due to an applied electric field.
R V, Davalos, I L M, Mir, B, Rubinsky
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Vessel Patency Post Irreversible Electroporation
CardioVascular and Interventional Radiology, 2014The purpose of the study was to evaluate the effect of Irreversible Electroporation (IRE) on vessel patency in close proximity to the ablation zone.Between January 2010 and November 2013, 101 patients underwent percutaneous IRE procedures using the NanoKnife for primary and metastatic tumors in different organs. Age ranged from 24 to 83 years.
Govindarajan, Narayanan +5 more
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Irreversible electroporation—Let's keep it cool
Journal of Cardiovascular Electrophysiology, 2018We thank Dr. Futyma for his attention to our manuscript 1 and the interesting discussion he provides in his letter 2 . This gives us the opportunity to further highlight the proposed non-thermal character of irreversible electroporation (IRE). Displacement of ohmic currents inside a tissue, a medium with an intrinsic impedance, will anytime, to some ...
Guido Caluori +3 more
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Irreversible electroporation ablation for atrial fibrillation
Journal of Cardiovascular Electrophysiology, 2018AbstractAtrial fibrillation (AF) is one of the most important problems in modern cardiology. Thermal ablation therapies, especially radiofrequency ablation (RF), are currently “gold standard” to treat symptomatic AF by localized tissue necrosis. Despite the improvements in reestablishing sinus rhythm using available methods, both success rate and ...
Adam Wojtaszczyk +4 more
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Irreversible Electroporation: Ready for Prime Time?
Techniques in Vascular and Interventional Radiology, 2013Image-guided ablation has evolved rapidly in the past decade into a competitive technique for treating focal solid malignancies. However, as they rely mainly on thermal energy, such as radiofrequency or microwave, many tumors close to sensitive organs, such as ducts, bowel, and nerves, still remain nonablatable owing to the risk of thermal injury ...
David S K, Lu +2 more
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Nonthermal Irreversible Electroporation for Tissue Decellularization
Journal of Biomechanical Engineering, 2010Tissue scaffolding is a key component for tissue engineering, and the extracellular matrix (ECM) is nature’s ideal scaffold material. A conceptually different method is reported here for producing tissue scaffolds by decellularization of living tissues using nonthermal irreversible electroporation (NTIRE) pulsed electrical fields to cause nanoscale ...
Mary, Phillips +2 more
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Irreversible Electroporation (IRE) in Renal Tumors
Current Urology Reports, 2016Small renal masses (SRMs) have been traditionally managed with surgical resection. Minimally invasive nephron-sparing treatment methods are preferred to avoid harmful consequences of renal insufficiency, with partial nephrectomy (PN) considered the gold standard.
Govindarajan, Narayanan, Mehul H, Doshi
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