Results 131 to 140 of about 66,017 (306)

Confocal Endomicroscopy Intestinal Epithelial Barrier Abnormalities in Individuals Without Documented Gastro‐Intestinal Disease

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background and aims Probe‐based confocal endomicroscopy (pCLE) allows real‐time microscopic visualization of the intestinal mucosa surface layers. Despite remission achieved through anti‐tumor necrosis factor or vedolizumab therapy, anomalies in the intestinal epithelial barrier are observed in inflammatory bowel disease (IBD) patients.
Thanh‐Hien Trieu   +5 more
wiley   +1 more source

Efficacy and safety of vibegron for the treatment of irritable bowel syndrome in women: Results of a randomized, double‐blind, placebo‐controlled phase 2 trial

open access: yesNeurogastroenterology &Motility, Volume 34, Issue 12, December 2022., 2022
In women with IBS‐D, vibegron was not associated with significant improvement in the percentage of API weekly responders. Vibegron was generally safe and well tolerated and, in particular, did not worsen IBS symptoms vs. placebo. Abstract Background Preclinical and clinical studies suggest that β3‐adrenergic receptor activation may be a novel target ...
Brian E. Lacy   +5 more
wiley   +1 more source

Long‐Term Impact of COVID‐19 on Disorders of Gut–Brain Interaction: Incidence, Symptom Burden, and Psychological Comorbidities

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic has highlighted the potential exacerbation of gastrointestinal symptoms in patients with disorders of gut‐brain interaction (DGBIs). However, the distinct symptom trajectories and psychological burden in patients with post‐COVID‐19 DGBIs compared with patients
Giovanni Marasco   +68 more
wiley   +1 more source

European Consensus on Malabsorption—UEG & SIGE, LGA, SPG, SRGH, CGS, ESPCG, EAGEN, ESPEN, and ESPGHAN

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac ...
Marco Vincenzo Lenti   +29 more
wiley   +1 more source

European Consensus on Malabsorption—UEG & SIGE, LGA, SPG, SRGH, CGS, ESPCG, EAGEN, ESPEN, and ESPGHAN. Part 1: Definitions, Clinical Phenotypes, and Diagnostic Testing for Malabsorption

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Malabsorption is a complex and multifaceted condition characterised by the defective passage of nutrients into the blood and lymphatic streams. Several congenital or acquired disorders may cause either selective or global malabsorption in both children and adults, such as cystic fibrosis, exocrine pancreatic insufficiency (EPI), coeliac ...
Marco Vincenzo Lenti   +29 more
wiley   +1 more source

Impact of Acute and Sub‐Acute Gluten Exposure on Gastrointestinal Symptoms and Psychological Responses in Non‐Coeliac Gluten Sensitivity: A Randomised Crossover Study

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Background/Aims Non‐coeliac gluten sensitivity (NCGS) is a controversial entity, characterised by symptom improvement with gluten exclusion in the absence of coeliac disease. We primarily investigated the effects of acute and sub‐acute gluten on psychological and mood profiles, with secondary outcomes examining gastrointestinal symptoms and ...
Julie Iven   +5 more
wiley   +1 more source

Faecalibacterium Diversity in the Gut Microbiome of Crohn's Disease Patients

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Faecalibacterium has recently garnered attention for its potential health implications. To better understand its role, we developed and assessed real‐time PCR assays for detecting and quantifying various Faecalibacterium species in human stool samples from both healthy individuals and Crohn's disease patients, either in flare or remission. The
Paul Mclellan   +16 more
wiley   +1 more source

Dissecting Microscopic Colitis Immunopathophysiology: Insights From Basic Research

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Microscopic colitis is an inflammatory bowel disease (IBD) comprising two clinically undiscernible entities: collagenous colitis and lymphocytic colitis. Collagenous colitis associates with HLA genes and displays a Th1/Tc1–Th17/Tc17 profile with pericryptal myofibroblast activity, water malabsorption and secondary fluid loss due to altered ...
Andreas Münch   +1 more
wiley   +1 more source

Psychological characteristics of patients with the irritable bowel syndrome

open access: green, 1974
R. L. Palmer   +4 more
openalex   +1 more source

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