Results 121 to 130 of about 109,910 (290)

The role of serotonin and melatonin in the development of clinical manifestations of functional gastrointestinal disorders associated with abdominal pain in children during wartime

Zdorovʹe Rebenka
Background. Functional dyspepsia and irritable bo­wel syndrome are the most prevalent functional gastrointestinal disorders among school-aged children.
N.A. Sliusar, S.P. Kryvopustov
doaj   +1 more source

Peripheral Mediators of Colorectal Nociception and Sensitization [PDF]

, 2012
Several ion channels are thought to facilitate colorectal afferent neuron sensitization, which contributes to abdominal pain in irritable bowel syndrome (IBS).
Kiyatkin, Michael E
core  

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Core stability in women with and without chronic pelvic pain

PM&R, EarlyView.
Abstract Background Physical activity (PA) and core stability levels are unknown for women with musculoskeletal chronic pelvic pain (CPP) compared to healthy women. At this time, there is no validated treatment method aimed specifically at CPP. Objective To elucidate the PA habits and core stability of women with and without CPP.
Hannah V. Chatwin, Abhilasha Kumar, Michael Wesolowski, Laura Glaser, Colleen M. Fitzgerald, Stacey Bennis   +5 more
wiley   +1 more source

Prevalence of irritable bowel syndrome in adolescents in Turkey: effects of gender, lifestyle and psychological factors

The Turkish Journal of Pediatrics, 2014
Scarce data exist concerning the prevalence of irritable bowel syndrome in adolescence. Changes in lifestyle, presence of stressors and psychological vulnerability during this stage of life place adolescents in the risk group for irritable bowel ...
Gökhan Baysoy, Nüket Güler-Baysoy, Aynur Kesicioğlu, Demet Akın, Tuğba Dündar, Ayten Pamukçu-Uyan   +5 more
doaj  

Epigenetic Regulation of Immune Dysfunction in Chronic Prostatitis/Chronic Pelvic Pain Syndrome

The Prostate, EarlyView.
ABSTRACT Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent and debilitating condition with unclear etiology. Increasing evidence implicates immune dysregulation, yet the molecular mechanisms underlying impaired immune regulation remain poorly defined. This study investigated the role of altered immune responses within
Praveen Thumbikat, Goutham Pattabiraman, Farzaneh Sharifzad, Yongyong Yang, Zhiqiang Liu, Catherine V. Osborn, Stephen F. Murphy, Qi Cao, Anthony J. Schaeffer   +8 more
wiley   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha (Withania somnifera) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale, Jaising Salve, John Ademola, Jose Parraca, Deepak Langade   +4 more
wiley   +1 more source

Predicting the severity symptoms in patients with irritable bowel syndrome based on temperament and character of personality. [PDF]

Taḥqīqāt-i ̒Ulūm-i Raftārī
Aim and Background: Irritable bowel syndrome is a chronic functional disease affected by various factors. Despite the effect of personality traits on the course of this disease, few studies have investigated the effect of personality traits on the ...
Niloofar Sadat Khatoonabadi, Ali Shariat, Maryam Sharifdoost   +2 more
doaj  

Effect of relaxation with drug therapy on the psychological symptoms in patients with irritable bowel syndrome-diarrhea dominant (IBS-D) [PDF]

, 2009
Background and aim: Irritable bowel syndrome is the most prevalent functional bowel disorder which is characterized by chronic abdominal pain and altered bowel habit in the absence of organic disease.
Adibi, Peyman., Afshar, Hamid., Kalantari, Mehrdad., Solati Dehkordi, Seyed kamal.   +3 more
core  

Impact of fibromyalgia on patient acceptable symptom state in Thai patients with spondyloarthritis: A cross‐sectional study

Rheumatology &Autoimmunity, EarlyView.
This cross‐sectional study enrolled Thai patients with spondyloarthritis to assess the prevalence and its impact. Fibromyalgia was present in 5.5% and significantly impaired health‐related quality of life and symptom perception. Low disease activity, good sleep quality, and FS < 3 were independently associated with achieving PASS.
Sittikorn Srivorrapattararkul, Praveena Chiowchanwisawakit   +1 more
wiley   +1 more source