Results 91 to 100 of about 108,365 (300)

Modulation of Lung Adenocarcinoma by Phosphorylated FOXN3‐Mediated Transcriptional Inactivation of p53

Advanced Science, EarlyView.
In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu, Jingyu Yu, Suhui Wang, Xinghong Hu, Lele Jin, Nan Wu, Yuhan Ni, Xueying Zhang, Chengling Zhao, Jihong Zhou, Yong Zhang, Baofa Sun, Hongxing Zhang, Chunfu Zheng, Song Guo Zheng, Wei Li, Xinxing Zhu   +16 more
wiley   +1 more source

Coordination‐Tuned Iridium Single‐Atom Nanozymes Boost Multienzyme Activity for Colorimetric Sensing

Advanced Science, EarlyView.
Breaking the coordination symmetry of Ir single‐atom sites through asymmetric Ir–N3S1 engineering tailors interfacial electron transfer, oxygen activation, and multienzyme‐like catalytic pathways. Operando spectroscopy and theoretical modeling uncover the atomic‐level origin of activity enhancement, providing a strategy for designing multifunctional ...
Tao Li, Xinyu Zhang, Jiashan Xia, Mengyu Wu, Cong Liu, Yapei Sun, Wanjiang Zhao, Min Qian, Wei Wang, Weixia Duan, Shangcheng Xu   +10 more
wiley   +1 more source

A Shared Control Approach to Robot-Assisted Cataract Surgery Training for Novice Surgeons

Sensors
This paper proposes a novel virtual-fixtures-based shared control concept for eye surgery systems focusing on cataract procedures, one of the most common ophthalmic surgeries.
Balint Varga, Michael Poncelet
doaj   +1 more source

Tag des offenen Denkmals im IRS Erkner: Führungen durch den Archivpavillon

, 2015
Das IRS Erkner und nicht zuletzt seine Wissenschaftlichen Sammlungen öffnen am 13. September 2015 ihre Türen. Anlass ist der deutschlandweite Tag des offenen Denkmals, zugleich begeht das IRS sein 20-jähriges Jubiläum am Standort Erkner mit einem Tag der
Kai Drewes, IRS Erkner
core  

Vanadium Cation Exchange‐Driven Reconstruction of MOF‐Derived Cobalt Hydroxide Electrodes for Electrocatalysis and Energy Storage

Advanced Science, EarlyView.
A room‐temperature vanadium cation exchange strategy is developed to achieve simultaneous structural reconstruction and electronic/defect modulation of ZIF‐67 on nickel foam. The resulting mesoporous V20–Co(OH)2 electrode exhibits superior OER activity with low overpotentials and enhanced lattice oxygen participation.
Yongbeen Kim, Seungwoo Han, Wonyoung Lee
wiley   +1 more source

HUKUK KLİNİKLERİ: DÜŞÜK GELİRLİ VERGİ MÜKELLEFLERİ KLİNİĞİ MODELİ

Artuklu Kaime
Temelde toplumsal hizmet anlayışını benimseyen hukuk klinikleri, hukuk fakültesi öğrencileri için de geliştirilen uygulamalı bir eğitim modelidir. Düşük gelirli vergi mükellefleri kliniği ise mükelleflerin temsil hakkını koruma, adil ve hakkaniyetli bir ...
Fatma Turna
doaj  

The Possibilities for Appraising Teachers’ Performance in the Perspective of Educational Policy and Organisational Culture

Eesti Majanduspoliitilised Väitlused, 2009
With the view to raising the effectiveness of Estonian educational system, new course concerning schools’ and pupils’ individual development must be taken.
Reelika Irs, Kulno Türk, Maaja Vadi
doaj   +1 more source

Kritisch Denken und Zeichnen für Architektur und Gesellschaft: Bruno Flierl im IRS Erkner

, 2017
Bruno Flierl mit einem der von ihm als Chefredakteur verantwortetem Hefte der Zeitschrift Deutsche Architektur aus dem Jahr 1962 Anfang Februar 2017 wurde der renommierte Berliner Architekturschriftsteller Bruno Flierl 90 Jahre alt.
Kai Drewes, IRS Erkner
core  

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Experience‐Dependent Reorganization of Hippocampal CA3 Neuronal Ensembles Associates With Memory Generalization

Advanced Science, EarlyView.
Mice can transfer the learned rule of spatial working memory to guide similar but novel tasks. Hippocampal CA3 populational activity dynamically reorganize during memory generalization, shifting from task‐specific to generalized coding over testing days. Sparse yet redundant neural representations of CA3 enable rule transfer and cognitive map formation,
Da Song, Zilu Zhu, Yujun Deng, Yujie Song, Hui Li, Junjun Ni, Zhenzhen Quan, Yan Yan, Hong Qing   +8 more
wiley   +1 more source