Results 101 to 110 of about 111,450 (307)
Advanced Science, EarlyView.The cathode of proton exchange membrane water electrolyzers remains a poorly understood region despite its importance for hydrogen purity and operational safety. Operando synchrotron X‐ray radiography directly visualizes liquid water behavior and uncovers a transition from continuous to pulsating transport, providing new insight into multiphase ...
Wataru Yoshimune +2 more
wiley +1 more source
GK and GKRP mRNA levels in livers from IRS-2(−/−), RIP-Irs-2/IRS-2(−/−) and their wild type mice.
, 2013 Levels of mRNA encoding GK (A) and GKRP (B) were measured in liver from IRS-2(−/−) or from RIP-Irs-2/IRS-2(−/−) and their wild-type mice. The bars represent means ± SE (n = 8 animals per experimental group).
Elvira Alvarez (396877) +7 more
core +1 more source
Selective Modulation of OTUB1 Noncanonical Function via a bioPhosTAC Strategy
Advanced Science, EarlyView.This work positions the versatile performance of the peptide‐based bioPhosTAC platform for dissecting phosphorylation‐dependent biology and expanding the scope of induced‐proximity technologies. We demonstrated that selective manipulation of a tyrosine phosphorylation site is sufficient to propagate coordinated cellular consequences.
Seung Un Seo +7 more
wiley +1 more source
CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1
Cell Reports, 2019 Summary: The tumor suppressor CYLD is a deubiquitinating enzyme that removes non-degradative ubiquitin linkages bound to a variety of signal transduction adaptors.
Tiphaine Douanne +5 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu +10 more
wiley +1 more source
Kritisch Denken und Zeichnen für Architektur und Gesellschaft: Bruno Flierl im IRS Erkner
, 2017 Bruno Flierl mit einem der von ihm als Chefredakteur verantwortetem Hefte der Zeitschrift Deutsche Architektur aus dem Jahr 1962 Anfang Februar 2017 wurde der renommierte Berliner Architekturschriftsteller Bruno Flierl 90 Jahre alt.
Kai Drewes, IRS Erkner
core
Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs
Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
wiley +1 more source
Advanced Science, EarlyView.Proposed molecular mechanism: NSUN6 catalyzes m5C methylation on Snail mRNA to enhance its stability, leading to Snail upregulation and EMT promotion. The first‐in‐class inhibitor AL398 suppresses endometrial cancer metastasis by targeting the NSUN6‐m5C‐Snail. axis. ABSTRACT Endometrial cancer (EC) constitutes a leading gynecologic malignancy for which
Xiangzhuan Zhao +19 more
wiley +1 more source
IRS expression in human lung adenocarcinoma.
, 2019 Representative H&E (A,D,G,J), IRS-1 (B,E,H,K) and IRS-2 (C,F,I,L) staining of the same tumors across each row. H&E images, magnification 4X; Larger IRS staining images, magnification 40x; IRS staining inset images, magnification 10X. Scale bar = 50um.
Jose Mercado-Matos (7164800) +6 more
core +1 more source