Results 101 to 110 of about 1,309,370 (384)

Avoidable Hospitalizations in Persons With Rheumatoid Arthritis: A Population‐Based Study Using Administrative Data

Arthritis Care &Research, EarlyView.
Objective We estimated incidence rates of avoidable hospitalizations by persons with rheumatoid arthritis (RA) relative to the general population. Methods We identified individuals meeting a validated case definition for RA based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) and ICD‐10‐CA codes in years ...
Dani G. Contreras, Claire E. H. Barber, J. Antonio Aviña‐Zubieta, Hude Quan, Seungwon Lee, James A. King, Cheryl Barnabe   +6 more
wiley   +1 more source

Myocardial infarct-sparing effect of ischemic preconditioning abrogated in cirrhotic rat through involvement of mitochondrial permeability transition pore [PDF]

, 2012
Despite all studies undertaken mechanism of cirrhotic cardiomyopathy the role of cirrhosis on ischemia-reperfusion (I/R) injury and ischemic preconditioning (IPC) phenomenon hasn't been explored yet.
Dehpour, A.R., Jafrazedeh, F., Khori, V., Mohimani, H.R., Mohsen, N.   +4 more
core  

Novel insights into the cardio-protective effects of FGF21 in lean and obese rat hearts [PDF]

, 2014
Aims: Fibroblast growth factor 21 (FGF21) is a hepatic metabolic regulator with pleotropic actions. Its plasma concentrations are increased in obesity and diabetes; states associated with an increased incidence of cardiovascular disease.
A Beenken, A Kharitonenkov, A Planavila, A Romero-Corral, A Sharma, AD Attie, AK Bose, Bee K. Tan, BK Tan, C Valina, C Yang, D Morabito, DJ Hausenloy, DR Riddell, E Braunwald, Edward W. Hillhouse, Emilio Hirsch, FM Fisher, G Nanayakkara, GC Rodrigo, GD Lopaschuk, H Jiao, H Li, Harpal S. Randeva, J Diaz-Delfin, J Mair, J Yie, J Yie, Jing Chen, JP Bertinchant, L Timmers, LC Clavijo, M Mraz, Manjunath Ramanjaneya, MC Mendoza, Muhammad F. Bari, N Shimizu, PK Shah, R Adya, R Mitra, Raghu Adya, S Doroudgar, S Kenchaiah, S Yusuf, SQ Liu, SQ Liu, Sunil K. Bhudia, T Matsui, T Nishimura, T Thim, T Uebanso, V Lionetti, Vanlata Patel, Y Ogawa, Y Wang   +54 more
core   +3 more sources

Hyperoxia Induced Alteration of Chromatin Structure in Human Bone Marrow Derived Primary Mesenchymal Stromal Cells

Advanced Biology, EarlyView.
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe, Samantha Kaonis, Natalie Calahan, Neda Kabi, Soham Ghosh   +4 more
wiley   +1 more source

Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research. [PDF]

, 2017
Acute ischemic stroke is a devastating cause of death and disability, consequences of which depend on the time from ischemia onset to treatment, the affected brain region, and its size.
Akyol, Onat, Applegate, Richard, Araujo, Camila, Ho, Wing Mann, Huang, Lei, Reis, Cesar, Zhang, John H   +6 more
core   +3 more sources

Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury.

Physiological Reviews, 2008
Mitochondria play an important role in cell death and cardioprotection. During ischemia, when ATP is progressively depleted, ion pumps cannot function resulting in a rise in calcium (Ca(2+)), which further accelerates ATP depletion.
E. Murphy, C. Steenbergen
semanticscholar   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Digital ischemia and tobacco

Pan African Medical Journal, 2017
An active smoker 50-year-old male with precedents of arterial hypertension, consulted for a month history of pain and severe vasomotor disorder in the right hand. Physical exam revealed preserved radial pulse and severe cyanosis in all fingers, especially evolved in the fourth and fifth ones (A).
Gallo-Padilla, Laura, Rios-Fernandez, Raquel   +1 more
openaire   +5 more sources

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

Intraoperative hyperglycemia augments ischemia reperfusion injury in renal transplantation: a prospective study. [PDF]

, 2011
Background. Diabetes is a risk factor for delayed graft function in kidney transplantation, and hyperglycemia increases ischemia reperfusion injury in animal models. Methods.
Dang, Kim, Hirose, Ryutaro, Niemann, Claus U, Parekh, Justin   +3 more
core   +5 more sources