Results 101 to 110 of about 931,368 (217)

Aging-associated Alteration in the Cardiac MIF-AMPK Cascade in Response to Ischemic Stress [PDF]

, 2008
An important role for a macrophage migration inhibitory factor (MIF)-AMP-activated protein kinase (AMPK) signaling pathway in ameliorating myocardial damage following ischemia/reperfusion has been described. An aging-associated reduction in AMPK activity
Erin Lane, Heng Ma, Ji Li, Jingying Wang, Jun Ren, Lin Leng, Richard Bucala, Wenkui Wang   +7 more
core   +1 more source

Coronary artery calcification and plaque stability： an optical coherence tomography study

Heliyon, 2023
Background: Coronary artery calcification (CAC), a surrogate of atherosclerosis, is related to stent underexpansion and adverse cardiac events. However, the effect of CAC on plaque stability is still controversial and the morphological significance of ...
Zhifeng Qin, Li Yu, Yanwen Zhang, Qinglu Xu, Chao Li, Suhong Zhao, Xiangwen Xi, Yanan Tian, Zhao Wang, Jinwei Tian, Bo Yu   +10 more
doaj  

Requirement for preclinical prioritization of neuroprotective strategies in stroke: Incorporation of preconditioning [PDF]

Conditioning Medicine, 2018, 2019
Acute neuroprotection in numerous human clinical trials has been an abject failure. Major systemic-and procedural-based issues have subsequently been identified in both clinical trials and preclinical animal model experimentation. As well, issues related to the neuroprotective moiety itself have contributed to clinical trial failures, including late ...
arxiv  

Prevalence and prognostic significance of DNMT3A- and TET2- clonal haematopoiesis-driver mutations in patients presenting with ST-segment elevation myocardial infarction

EBioMedicine, 2022
Summary: Background: Clonal haematopoiesis driven by mutations in DNMT3A or TET2 has recently been identified as a new risk factor for cardiovascular disease.
Shengfang Wang, Sining Hu, Xing Luo, Xiaoyi Bao, Ji Li, Minghao Liu, Ying Lv, Chen Zhao, Ming Zeng, Xi Chen, Amanda Unsworth, Sarah Jones, Thomas W. Johnson, Stephen J. White, Haibo Jia, Bo Yu   +15 more
doaj  

The effect of ischemia on the peripheral nerve action potential in man and its relation to somatosensory magnitude coding [PDF]

, 1967
William R. Uttal
openalex   +1 more source

Corrigendum: C1q/TNF-Related Protein 9 Attenuates Atherosclerosis by Inhibiting Hyperglycemia-Induced Endothelial Cell Senescence Through the AMPKα/KLF4 Signaling Pathway

Frontiers in Pharmacology, 2021
Gang Wang, Gang Wang, Baihe Han, Baihe Han, Ruoxi Zhang, Qi Liu, Qi Liu, Xuedong Wang, Xuedong Wang, Xingtao Huang, Xingtao Huang, Dandan Liu, Dandan Liu, Weishen Qiao, Weishen Qiao, Mengyue Yang, Mengyue Yang, Xing Luo, Xing Luo, Jingbo Hou, Jingbo Hou, Bo Yu, Bo Yu   +22 more
doaj   +1 more source

A novel anti-atherosclerotic mechanism of quercetin: Competitive binding to KEAP1 via Arg483 to inhibit macrophage pyroptosis

Redox Biology, 2022
Natural antioxidants represented by quercetin have been documented to be effective against atherosclerosis. However, the related mechanisms remain largely unclear.
Xing Luo, Xiuzhu Weng, Xiaoyi Bao, Xiaoxuan Bai, Ying Lv, Shan Zhang, Yuwu Chen, Chen Zhao, Ming Zeng, Jianxin Huang, Biyi Xu, Thomas W. Johnson, Stephen J. White, Ji Li, Haibo Jia, Bo Yu   +15 more
doaj  

A Deep Learning Approach to Examine Ischemic ST Changes in Ambulatory ECG Recordings. [PDF]

, 2018
Patients with suspected acute coronary syndrome (ACS) are at risk of transient myocardial ischemia (TMI), which could lead to serious morbidity or even mortality.
Hu, Xiao, Mortara, David W, Pelter, Michele M, Xiao, Ran, Xu, Yuan   +4 more
core  

The Pathogenesis of Transient Focal Cerebral Ischemia [PDF]

, 1965
Clark H. Millikan
openalex   +1 more source

Long-Term Results of Endarterectomy of the Internal Carotid Artery for Cerebral Ischemia and Infarction [PDF]

, 1967
Albert Heyman, W. Glenn Young, Ivan W. Brown, K. S. Grimson   +3 more
openalex   +1 more source