Results 111 to 120 of about 999,788 (310)
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
Ischemia and reperfusion—from mechanism to translation
Nature Medicine, 2011 H. Eltzschig, T. Eckle
semanticscholar +1 more source
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
Attenuation of Focal Cerebral Ischemic Injury Following Post Ischemic Inhibition of Angiotensin Converting Enzyme (ACE) Activity in Normotensive Rat [PDF]
Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from ...
دهقان, غلامعباس +1 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
Nmda Receptor Blocker Ameliorates Ischemia-Reperfusion-Induced Renal Dysfunction in Rat Kidneys
, 2011 N-methyl-D-aspartate (NMDA) receptor activated by glutamate/ glycine is located in the kidneys. The NMDA receptor subunit NR1 is increased in damaged renal tissue.
楊芝青;鄭劍廷;吳明修;馬明傑;陳朝峰 +1 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective We investigated whether a diagnosis of rheumatoid arthritis (RA) affects the quality of inpatient acute myocardial infarction (AMI) care and long‐term mortality post‐AMI. Methods We analyzed data from 784,091 adults, 6,047 with a diagnosis of RA, from England and Wales hospitalized with AMI between 2005 and 2019 from the Myocardial Ischaemia ...
Megan Butler +8 more
wiley +1 more source
Acute lower limb ischemia - reperfusion injury
, 2022 Acute limb ischemia (ALI) occurs when there is a sudden reduction in limb perfusion due to an occlusion of peripheral arterial obstruction. The aim of the thesis is to give a brief overview on acute lower limb ischemia-reperfusion injury, involving ...
Do, Trung Anh
core
Rheumatologic Manifestations of Patients With Type B Insulin Resistance
Arthritis Care &Research, EarlyView.Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya +4 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin +14 more
wiley +1 more source