Results 101 to 110 of about 543,435 (265)

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Comprehensive age-specific metabolic phenotyping in myocardial infarction

BMC Cardiovascular Disorders
Aging is a main risk factor for the development of myocardial infarction (MI), with worse clinical outcomes. However, the understanding of age-related metabolic profiles in MI remains unclear. This study aimed to identify the clinical implications of age-
Xiaoxuan Bai, Ming Zeng, Tianyu Wu, Ying Lv, Chen Zhao, Xing Luo, Boling Yi, Huahui Ren, Yixuan Zhang, Liangxiao Xu, Xiuzhu Weng, Shan Zhang, Yuxiao Zhu, Sining Hu, Bo Yu, Haibo Jia   +15 more
doaj   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

Impact of residual cholesterol and inflammation risk on non-culprit plaque progression in patients with acute coronary syndrome: a serial optical coherence tomography study

BMC Cardiovascular Disorders
Background Acute Coronary Syndrome (ACS) patients face recurrent cardiovascular events due to non-culprit plaque progression despite optimal secondary prevention, but the differential impacts of residual cholesterol risk (RCR, on-treatment LDL-C ≥ 1 ...
Dirui Zhang, Luping He, Boling Yi, Yishuo Xu, Chen Zhao, Ming Zeng, Yuhan Qin, Ziqian Weng, Ning Wang, Xue Feng, Lulu Li, Yini Wang, Jingbo Hou, Gary S Mintz, Sining Hu, Haibo Jia, Bo Yu   +16 more
doaj   +1 more source

Multiwavelength Implantable Oximeter for Wireless Monitoring of Tissue Oxygenation in the Presence of Blood Volume Changes

Advanced Healthcare Materials, EarlyView.
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky, Hugo L. Higueros‐Garcia, Sadi Loai, Samantha Unger, Jacob Trueb, Yonatan Usatinsky, Rawad Alkallas‐Valdiviezo, Noor Abu Jarad, Jonathan Wu, Hai‐Ling M. Cheng, John A. Rogers, Abraham Vázquez‐Guardado, Daniel Franklin   +12 more
wiley   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

The legacy of ISCHEMIA

Cardiology Journal, 2020
Ianni U., Radico F., Ricci F., Perfetti M., Archilletti F., Renda G., Maddestra N., Gallina S., Zimarino M.   +8 more
openaire   +3 more sources

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Corrigendum: Higher serum phosphorus and calcium levels provide prognostic value in patients with acute myocardial infarction

Frontiers in Cardiovascular Medicine, 2022
Wei Cao, Wei Cao, Yilan Li, Yilan Li, Yao Wen, Shaohong Fang, Shaohong Fang, Bing Zhao, Bing Zhao, Xiaoyuan Zhang, Xiaoyuan Zhang, Yanxiu Zhang, Yanxiu Zhang, Xueyan Lang, Xueyan Lang, Bo Yu, Bo Yu, Yao Zhang, Yao Zhang   +18 more
doaj   +1 more source