Results 211 to 220 of about 1,184,407 (410)

The prognostic value of clinical frailty scale and outcomes in older patients undergoing left ventricular assist device implantation

AGING MEDICINE, Volume 5, Issue 4, Page 257-263, December 2022., 2022
The main finding in our study is that Clinical Frailty Scale‐defined frailty status was predictive of 1‐year post‐interventional mortality after left ventricular assist device implantation. Abstract Objectives Heart failure impacts patients’ functional capabilities, ultimately leading to frailty.
Temitope Ajibawo, Priyank Chauhan, Radha S. Gopalan, Nimit K. Agarwal   +3 more
wiley   +1 more source

Low‐intensity pulsed ultrasound improves myocardial ischaemia‒reperfusion injury via migrasome‐mediated mitocytosis

Clinical and Translational Medicine
During myocardial ischaemia‒reperfusion injury (MIRI), the accumulation of damaged mitochondria could pose serious threats to the heart. The migrasomes, newly discovered mitocytosis‐mediating organelles, selectively remove damaged mitochondria to provide
Ping Sun, Yifei Li, Weidong Yu, Jianfeng Chen, Pingping Wan, Zhuo Wang, Maomao Zhang, Chao Wang, Shuai Fu, Ge Mang, Stephen Choi, Zhuo Du, Caiying Tang, Song Li, Guoxia Shi, Jiawei Tian, Jiannan Dai, Xiaoping Leng   +17 more
doaj   +1 more source

The Pathogenesis of Transient Focal Cerebral Ischemia [PDF]

, 1965
Clark H. Millikan
openalex   +1 more source

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

Advanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du, Muhammad Rafiq, Hui Yuan, Xiangmin Li, Sheng Wang, Jun Wu, Jinfeng Wei, Ren‐Ke Li, Huiming Guo, Burton B Yang   +9 more
wiley   +1 more source

Prescription analgesic overuse in older adults: Can we mitigate this growing problem?

AGING MEDICINE, Volume 5, Issue 4, Page 294-296, December 2022., 2022
With older adults already on numerous prescription medications to manage their chronic conditions, the addition of pain medications could impose an even greater burden due to dependency issues. We need to understand the use of chronic pain medication, especially opioids, discuss current strategies and gaps, and offer potential solutions to mitigate ...
Sara Kakatkar, Aditya Narayan, Rajesh Balkrishnan   +2 more
wiley   +1 more source

Effect of Coronary Vasodilator Drugs on Retrograde Flow in Areas of Chronic Myocardial Ischemia

, 1964
Wadie M. Fam, Maurice McGregor
openalex   +1 more source

P21‐Activated Kinase 2 as a Novel Target for Ventricular Tachyarrhythmias Associated with Cardiac Adrenergic Stress and Hypertrophy

Advanced Science, EarlyView.
Ca2+/calmodulin‐dependent kinase II (CaMKII) activation is likely driven by oxidative stress, particularly excessive reactive oxygen species (ROS) production. This study identifies P21‐activated kinase 2 (Pak2) as a novel regulator of ROS‐induced CaMKII activation and abnormal Ca2⁺ dynamics in acute adrenergic and chronic pressure‐overload stressed ...
Tao Li, Ting Liu, Yan Wang, Yangpeng Li, Leiying Liu, James Bae, Yu He, Xian Luo, Zhu Liu, Tangting Chen, Xianhong Ou, Dan Zhang, Huan Lan, Juyi Wan, Yan Wei, Fang Zhao, Xin Wang, Tao Li, Christopher L.‐H. Huang, Chunxiang Zhang, Ming Lei, Xiaoqiu Tan   +21 more
wiley   +1 more source

A pilot randomized controlled trial of WeiNaoKang (SaiLuoTong) in treating vascular dementia

AGING MEDICINE, Volume 5, Issue 4, Page 246-256, December 2022., 2022
A 16‐week randomized double‐blind, placebo‐controlled trial for vascular dementia was carried out with WeiNaoKang (or SaiLuoTong). There were significant differences in improvement in cognitive function and activities of daily living, favouring the treatment group.
Junguang Liu, Dennis Chang, Dennis Cordato, Kien Lee, Hugh Dixson, Alan Bensoussan, Daniel Kam Yin Chan   +6 more
wiley   +1 more source

Instrumental Variables with Time-Varying Exposure: New Estimates of Revascularization Effects on Quality of Life [PDF]

arXiv
The ISCHEMIA Trial randomly assigned patients with ischemic heart disease to an invasive treatment strategy centered on revascularization with a control group assigned non-invasive medical therapy. As is common in such ``strategy trials,'' many participants assigned to treatment remained untreated while many assigned to control crossed over into ...
arxiv  

Comparative Study of Effects of Levarterenol and Methoxamine in Shock Associated with Acute Myocardial Ischemia in Dogs [PDF]

, 1962
James W. West, Arthur T. Faulk, Santiago V. Guzmán   +2 more
openalex   +1 more source