Results 221 to 230 of about 1,043,947 (356)

COCHLEAR ISCHEMIA AND CHANGES IN COMPOUND ACTION POTENTIALS IN THE GUINEA PIG

, 1996
Anzhou Tang, Masaharu Ura, Masayuki YAMAUCHI, Yutaka Noda   +3 more
openalex   +2 more sources

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

Upregulation of mesencephalic astrocyte-derived neurotrophic factor in glial cells is associated with ischemia-induced glial activation [PDF]

, 2012
Yujun Shen, Aimin Sun, Yun-Hong Wang, Da-Qin Cha, Haiping Wang, Facai Wang, Lijie Feng, Shengyun Fang, Yuxian Shen   +8 more
openalex   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Unusual painless upper limb ischemia in a patient with diabetes. A case study. [PDF]

Diab Vasc Dis Res
Pyrkosz J, Augustynowicz G, Kisiel M, Rabczyński M, Pochciał P, Madziarska K.   +5 more
europepmc   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

​​Breaking the Bowel: A Subacute Ischemic Complication of Chronic Methamphetamine Use. [PDF]

Cureus
Moran B, Scotto T, Sheikh S.
europepmc   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Sex differences in cardiac graft recovery and pathophysiologic changes in a rat model of donation after circulatory death. [PDF]

Sci Rep
Clavier A, Graf S, Helmer A, Lagger D, Egle M, Segiser A, Siepe M, Arnold M, Longnus S.   +8 more
europepmc   +1 more source

370. Evaluation of Dynamic CT for cerebral ischemia

, 1992
Takusi Ookubo, Keiichi Machida, Hideharu Nakano, Yasuo Moriguchi, Mitsuru Honda   +4 more
openalex   +2 more sources