Results 51 to 60 of about 107,429 (283)

Engineering Topographical Cues to Enhance Neural Regeneration in Spinal Cord Injury: Overcoming Challenges and Advancing Therapies

Advanced Functional Materials, EarlyView.
Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu, Fenghui Wang, Joshua Stein, Siqiao Wang, Pengfei Jiang, Letao Yang, Liming Cheng, Ki‐Bum Lee   +7 more
wiley   +1 more source

Current and Projected Burden of Ischemic Cerebrovascular Events: Nationwide Estimates From the Dijon Stroke Registry, France

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background This study aimed to assess attack rates of ischemic cerebrovascular events (CVEs) in a population‐based registry and to estimate the current and projected burden of the disease in whole France.
Yannick Béjot, Gauthier Duloquin
doaj   +1 more source

Can Emergency Physicians Perform Carotid Artery Point-of-Care Ultrasound to Detect Stenosis in Patients with TIA and Stroke? A Pilot Study [PDF]

, 2020
Introduction: Patients with severe, symptomatic carotid stenosis can have their subsequent stroke risk reduced by surgical intervention if performed soon after a transient ischemic attack (TIA) or stroke.
Nemnom, Marie-Joe, Park, Lily, Perry, Jeffrey J., Stotts, Grant, Suttie, Robert, Woo, Michael Y.   +5 more
core  

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source

Relationship of national institutes of health stroke scale to 30-day mortality in medicare beneficiaries with acute ischemic stroke. [PDF]

, 2012
BackgroundThe National Institutes of Health Stroke Scale (NIHSS), a well-validated tool for assessing initial stroke severity, has previously been shown to be associated with mortality in acute ischemic stroke.
Broderick, Joseph P, Fonarow, Gregg C, Hernandez, Adrian F, Kleindorfer, Dawn O, Olson, Daiwai M, Pan, Wenqin, Peterson, Eric D, Sacco, Ralph L, Saver, Jeffrey L, Schwamm, Lee H, Smith, Eric E   +10 more
core   +1 more source

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

Advanced Healthcare Materials, EarlyView.
This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis, Vignesh Jayarajan, George M. Church, Roger D. Kamm, João Pedro de Magalhães, Emad Moeendarbary   +5 more
wiley   +1 more source

Six-Month Outcome of Transient Ischemic Attack and Its Mimics

Frontiers in Neurology, 2019
Background and Objective: Although the risk of recurrent cerebral ischemia is higher after a transient ischemic attack (TIA), there is limited data on the outcome of TIA mimics.
Alireza Sadighi, Vida Abedi, Alia Stanciu, Nada El Andary, Mihai Banciu, Neil Holland, Ramin Zand   +6 more
doaj   +1 more source

A clinical case of successful treatment of coronary artery dissection and left ventricular thrombosis in a young man carrier of factor V Leiden gene and transient ischemic attack

Архивъ внутренней медицины, 2023
One of the causes of transient ischemic attack or ischemic stroke are mass formations in the left heart. One of the predisposing factors for thrombosis is the presence of the Leiden mutation, as the most common form of hereditary thrombophilia in the ...
S. T. Enginoev, Yu. B. Martyanova, E. V. Efremova, I. I. Chernov   +3 more
doaj   +1 more source

Context-based task ontologies for clinical guidelines [PDF]

, 2004
Evidence-based medicine relies on the execution of clinical practice guidelines and protocols. A great deal of of effort has been invested in the development of various tools which automate the representation and execution of the recommendations ...
Ciccarese, Paolo, Kumar, Anand, Piazza, Matteo, Smith, Barry   +3 more
core  

Aging-Related Decline of Glutathione Peroxidase 3 and Risk of Cardiovascular Events in Patients With Atrial Fibrillation [PDF]

, 2016
BACKGROUND: Experimental studies demonstrated that glutathione peroxidase 3 (GPx3), an antioxidant enzyme that catabolizes hydrogen peroxide, protects against thrombosis. Little is known about its role in cardiovascular disease. METHODS AND RESULTS:
Carnevale, Roberto, Farcomeni, Alessio, Menichelli, Danilo, Nocella, Cristina, Pastori, Daniele, Pignatelli, Pasquale, Violi, Francesco   +6 more
core   +1 more source