Results 101 to 110 of about 106,174 (376)

Guideline‐directed medical therapy in patients undergoing transcatheter edge‐to‐edge repair for secondary mitral regurgitation

open access: yesEuropean Journal of Heart Failure, Volume 24, Issue 11, Page 2152-2161, November 2022., 2022
Triple guideline‐directed medical therapy (GDMT) prescription was associated with a lower 2‐year mortality compared to non‐triple GDMT prescription (A). Such association was observed in patients with concomitant comorbidities (B). CI, confidence interval; CKD, chronic kidney disease; CMP, cardiomyopathy; HR, hazard ratio; MRA, mineralocorticoid ...
Satoshi Higuchi   +36 more
wiley   +1 more source

Impaired mitochondrial biogenesis is a common feature to myocardial hypertrophy and end-stage ischemic heart failure [PDF]

open access: yes, 2016
Mitochondrial (mt) DNA depletion and oxidative mtDNA damage have been implicated in the process of pathological cardiac remodeling. Whether these features are present in the early phase of maladaptive cardiac remodeling, that is, during compensated ...
Bargelli, Valentina   +16 more
core   +3 more sources

Multimodality Imaging in Ischemic Cardiomyopathy [PDF]

open access: yesActa Universitatis Cibiniensis. Technical Series, 2019
AbstractIschemic heart disease is the most common heart pathology in medical practice. Proper assessment of the size of myocardium injury and its consequences on the heart function is extremely important both for a correct drug therapy and for interventional approach. Most frequently the left ventricle is affected.
Gabriela Eminovici   +3 more
openaire   +2 more sources

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

open access: yesAdvanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li   +11 more
wiley   +1 more source

Use of guideline‐recommended medical therapy in patients with heart failure and chronic kidney disease: from physician's prescriptions to patient's dispensations, medication adherence and persistence

open access: yesEuropean Journal of Heart Failure, Volume 24, Issue 11, Page 2185-2195, November 2022., 2022
Patients with heart failure and chronic kidney disease are less likely to receive and persist on guideline‐recommended medical therapies. Aim Half of heart failure (HF) patients have chronic kidney disease (CKD) complicating their pharmacological management.
Roemer J. Janse   +9 more
wiley   +1 more source

EFFECT OF BETA-BLOCKERS AND STUDY OF AGGREGATiVE ACTIVITY OF THROMBOCYTES IN PATiENTS WITH DILATED CARDIOMYOPATHY

open access: yesActa Biomedica Scientifica, 2012
The aim. was to study peculiarities of ischemic and idiopathic dilated cardiomyopathy and. aggregative activity of thrombocytes and. also the response to the therapy by beta-blockers (Atenolol and Bisoprolol). Material and.
P. N. Isakhanova, Yu. N. Ziyaev
doaj  

The habitual use of plant alkaloids and the prevalence of myocardial diseases.

open access: yesمجلة كلية الطب, 2010
Background: The plant (Khat) contains at least 40 types of alkaloids. It has an adrenergic like effect especially on the heart one of these alkaloid is cathedulins group which has molecular height of 600- 1200mm.I/L.
Basil N. Saeed
doaj   +1 more source

Fatty images of the heart: spectrum of normal and pathological findings at computed tomography and cardiac magnetic resonance imaging. [PDF]

open access: yes, 2018
Ectopic cardiac fatty images are not rarely detected incidentally at computed tomography and cardiac magnetic resonance, either in exams focused on the heart as in general thoracic imaging evaluations.
Cannavale, Giuseppe   +6 more
core   +3 more sources

Reversal of Stress‐Induced PIEZO1 Elevation with Mechanically Adapted Epicardial Patch for Myocardial Infarction Treatment

open access: yesAdvanced Science, EarlyView.
This work identifies fine‐tuning the expression of PIEZO1 as a critical molecular mechanism underlying the treatment of myocardial infarction by mechanically adapted cardiac patches, which can support the clinical translation of cardiac patch devices.
Yuwen Lu   +18 more
wiley   +1 more source

Trajectories in New York Heart Association functional class in heart failure across the ejection fraction spectrum: data from the Swedish Heart Failure Registry

open access: yesEuropean Journal of Heart Failure, Volume 24, Issue 11, Page 2093-2104, November 2022., 2022
Stable New York Heart Association (NYHA) class over time was much more frequent than an improvement or a worsening. Follow‐up NYHA class assessment, but not change in NYHA class over time, was independently associated with better prognosis. CI, confidence interval; HR, hazard ratio.
Felix Lindberg   +7 more
wiley   +1 more source

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