Results 71 to 80 of about 106,174 (376)

Image Classification of Stroke Blood Clot Origin using Deep Convolutional Neural Networks and Visual Transformers [PDF]

arXiv, 2023
Stroke is one of two main causes of death worldwide. Many individuals suffer from ischemic stroke every year. Only in US more over 700,000 individuals meet ischemic stroke due to blood clot blocking an artery to the brain every year. The paper describes particular approach how to apply Artificial Intelligence for purposes of separating two major acute ...
arxiv  

A Novel Protein NAB1‐356 Encoded by circRNA circNAB1 Mitigates Atrial Fibrillation by Reducing Inflammation and Fibrosis

Advanced Science, EarlyView.
The circRNA circNAB1 is downregulated in AF patient. Silencing circNAB1 promotes collagen deposition and inflammation, whereas overexpression reduces AF susceptibility. circNAB1 encodes the protein NAB1 356 that interacts with EGR1 to mitigate fibrosis and inflammation.
William W Du, Muhammad Rafiq, Hui Yuan, Xiangmin Li, Sheng Wang, Jun Wu, Jinfeng Wei, Ren‐Ke Li, Huiming Guo, Burton B Yang   +9 more
wiley   +1 more source

Improved costs and outcomes with conscious sedation vs general anesthesia in TAVR patients: Time to wake up? [PDF]

, 2017
BackgroundTranscatheter aortic valve replacement (TAVR) has become a commonplace procedure for the treatment of aortic stenosis in higher risk surgical patients.
Aksoy, Olcay, Benharash, Peyman, Fernandez, Josue, Johansen, Daniel, Kwon, Murray, Patel, Komal D, Sareh, Sohail, Satou, Nancy, Shemin, Richard J, Suh, William, Toppen, William   +10 more
core   +3 more sources

CARDIOMYOPATHY IN ACUTE ISCHEMIC STROKE

Journal of the American College of Cardiology, 2013
Cardiomyopathy (CM) in patients admitted with acute ischemic stroke has not been investigated previously. A prospective registry of 1,761 patients admitted with diagnosis of acute ischemic stroke from 2009-2010 was used to identify patients with systolic CM.
Gavin Hickey, Hunter C. Champion, Mark Schmidhofer, Zeina Dardari, Tudor G Jovin, Sandeep Patel, Maxim D. Hammer, Vivek Y. Reddy, Nadeem Kolia, Bhavna Balaney, Omar Batal   +10 more
openaire   +2 more sources

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Integrative Multi‐Omics and Routine Blood Analysis Using Deep Learning: Cost‐Effective Early Prediction of Chronic Disease Risks

Advanced Science, EarlyView.
Omicsformer, a deep learning model, integrates multi‐omics and routine blood data to accurately predict risks for nine chronic diseases, including cancer and cardiovascular conditions. Validated using large scale clinical data, it reveals early risk trajectories, advancing personalized medicine and offering a cost‐effective, community‐based solution ...
Zhibin Dong, Pei Li, Yi Jiang, Zhihan Wang, Shihui Fu, Hebin Che, Meng Liu, Xiaojing Zhao, Chunlei Liu, Chenghui Zhao, Qin Zhong, Chongyou Rao, Siwei Wang, Suyuan Liu, Dayu Hu, Dongjin Wang, Juntao Gao, Kai Guo, Xinwang Liu, En Zhu, Kunlun He   +20 more
wiley   +1 more source

Contrast-Enhanced Cardiac Magnetic Resonance Imaging Accurately Differentiates Ischemic from Non-Ischemic Etiologies in Newly Diagnosed Cardiomyopathy

Clinical Medicine Insights: Cardiology, 2008
Objective Patients with newly diagnosed cardiomyopathy frequently undergo coronary angiography to exclude significant coronary artery disease (CAD). Contrast-enhanced cardiac magnetic resonance imaging (CE-CMR) can detect myocardial scar in-vivo, and has
Jonathan P. Christiansen, Colin Edwards, Guy P. Armstrong, Anthony Scott, Hitesh Patel, Hamish Hart   +5 more
doaj   +1 more source

Sudden cardiac death in patients with ischemic heart failure undergoing coronary artery bypass grafting results from the STICH randomized clinical trial (Surgical Treatment for Ischemic Heart Failure) [PDF]

, 2017
Background—The risk of sudden cardiac death (SCD) in patients with heart failure following CABG has not been examined in a contemporary clinical trial of surgical revascularization. This analysis describes the incidence, timing and clinical predictors of
Al-Khatib, Sana M., Carson, Peter E., Cleland, John G.F., Desvigne-Nickens, Patrice M., Feldman, Arthur M., Lang, Irene M., Lee, Kerry L., Nicolau, Jose C., Pokorney, Sean, Rao, Meena P., Romanov, Alexander, Rouleau, Jean L., Selzman, Craig H., She, Lilin, Siepe, Matthias, Stepinska, Janina, Sueta, Carla, Tungsubutra, Wiwun, Velazquez, Eric J., Yii, Michael   +19 more
core   +2 more sources

KLF1 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through Regulation of Wnt/β‐Catenin Signaling Pathway

Advanced Science, EarlyView.
In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao, Xi Zhang, Shuan Ran, Yuan Li, Weicong Ye, Song Wang, Xiaohan Li, Zilong Luo, Jiulu Zhao, Junjie Zong, Kexiao Zheng, Ran Li, Han Zhang, Longyong Lai, Pinyan Huang, Zifeng Zou, Wang Zhan, Zhang Yue, Jie Wu, Jiahong Xia   +19 more
wiley   +1 more source

Role of cardiac MRI in assessment of patients with dilated cardiomyopathy

The Egyptian Journal of Radiology and Nuclear Medicine, 2017
Purpose: To study additive role of CMR to echocardiography in assessment of dilated cardiomyopathy and if LGE-CMR myocardial enhancement pattern can differentiate between ischemic and non-ischemic dilated cardiomyopathy compared to coronary ...
Heba R. Ibrahim, Ahmed M. Housseini, Tarek H. Khalil, Khalid E. Allam, Hesham H. Ali   +4 more
doaj   +1 more source